Thumpd2 (THUMP domain containing 2) - Rat Genome Database

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Gene: Thumpd2 (THUMP domain containing 2) Rattus norvegicus
Analyze
Symbol: Thumpd2
Name: THUMP domain containing 2
RGD ID: 1306878
Description: Predicted to enable snRNA methyltransferase activity and tRNA (guanine) methyltransferase activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome and tRNA methylation. Predicted to be part of tRNA methyltransferase complex. Predicted to be active in nucleus. Orthologous to human THUMPD2 (THUMP domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313851; MGC108999; THUMP domain-containing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8619,677,039 - 19,728,947 (+)NCBIGRCr8
mRatBN7.2613,924,742 - 13,976,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl613,924,765 - 13,976,657 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx614,228,394 - 14,280,284 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0614,551,389 - 14,596,793 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0614,041,656 - 14,093,548 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.063,743,080 - 3,794,512 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl63,743,074 - 3,794,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.063,710,777 - 3,762,198 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.463,974,995 - 4,026,884 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.163,974,998 - 4,026,884 (-)NCBI
Celera613,611,109 - 13,658,637 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Thumpd2RatLynch syndrome  ISOTHUMPD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary nonpolyposis colorectal neoplasmsClinVarPMID:28492532
Thumpd2RatNeurodevelopmental Disorders  ISOTHUMPD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868

1 to 20 of 31 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Thumpd2Rat1,2-dimethylhydrazine increases expressionISOThumpd2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of THUMPD2 mRNACTDPMID:22206623
Thumpd2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOThumpd2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of THUMPD2 mRNACTDPMID:19465110
Thumpd2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of THUMPD2 mRNACTDPMID:21215274
Thumpd2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of THUMPD2 mRNA]CTDPMID:21215274
Thumpd2Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of THUMPD2 mRNACTDPMID:21346803
Thumpd2Rat4,4'-sulfonyldiphenol decreases expressionISOThumpd2 (Mus musculus)6480464bisphenol S results in decreased expression of THUMPD2 mRNACTDPMID:39298647
Thumpd2Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of THUMPD2 mRNACTDPMID:30047161
Thumpd2Rataflatoxin B1 increases expressionISOThumpd2 (Mus musculus)6480464Aflatoxin B1 results in increased expression of THUMPD2 mRNACTDPMID:19770486
Thumpd2Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of THUMPD2 mRNACTDPMID:30047161
Thumpd2Ratamphetamine decreases expressionEXP 6480464Amphetamine results in decreased expression of THUMPD2 mRNACTDPMID:30779732
Thumpd2Ratarsenite(3-) multiple interactionsISOTHUMPD2 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to THUMPD2 mRNA]CTDPMID:32406909
Thumpd2Ratbenzo[a]pyrene decreases methylationISOTHUMPD2 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of THUMPD2 promoterCTDPMID:27901495
Thumpd2Ratbeta-hexachlorocyclohexane decreases expressionISOThumpd2 (Mus musculus)6480464beta-hexachlorocyclohexane results in decreased expression of THUMPD2 mRNACTDPMID:25270620
Thumpd2Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of THUMPD2 mRNACTDPMID:25181051
Thumpd2Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of THUMPD2 geneCTDPMID:28505145
Thumpd2Ratcadmium dichloride decreases expressionISOTHUMPD2 (Homo sapiens)6480464Cadmium Chloride results in decreased expression of THUMPD2 mRNACTDPMID:38568856
Thumpd2Ratcylindrospermopsin increases expressionISOTHUMPD2 (Homo sapiens)6480464cylindrospermopsin results in increased expression of THUMPD2 mRNACTDPMID:24921660
Thumpd2Ratdicrotophos decreases expressionISOTHUMPD2 (Homo sapiens)6480464dicrotophos results in decreased expression of THUMPD2 mRNACTDPMID:28302478
Thumpd2Ratgentamycin increases expressionEXP 6480464Gentamicins results in increased expression of THUMPD2 mRNACTDPMID:33387578
Thumpd2Ratleflunomide increases expressionISOTHUMPD2 (Homo sapiens)6480464leflunomide results in increased expression of THUMPD2 mRNACTDPMID:28988120

1 to 20 of 31 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Thumpd2Ratmethylation involved_inIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Thumpd2Ratregulation of alternative mRNA splicing, via spliceosome involved_inIEAUniProtKB:Q9BTF0 and ensembl:ENSP000004239331600115GO_REF:0000107EnsemblGO_REF:0000107
Thumpd2Ratregulation of alternative mRNA splicing, via spliceosome involved_inISOTHUMPD2 (Homo sapiens)1624291 PMID:37283053RGDPMID:37283053
Thumpd2RatRNA processing involved_inIEAARBA:ARBA000282231600115GO_REF:0000117UniProtGO_REF:0000117
Thumpd2RattRNA methylation involved_inIBAPANTHER:PTN000382878 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Thumpd2Ratnucleus is_active_inISOTHUMPD2 (Homo sapiens)1624291 PMID:34948388RGDPMID:34948388
Thumpd2Ratnucleus is_active_inIEAUniProtKB:Q9BTF0 and ensembl:ENSP000004239331600115GO_REF:0000107EnsemblGO_REF:0000107
Thumpd2RattRNA methyltransferase complex part_ofIEAUniProtKB:Q9BTF0 and ensembl:ENSP000004239331600115GO_REF:0000107EnsemblGO_REF:0000107
Thumpd2RattRNA methyltransferase complex part_ofISOTHUMPD2 (Homo sapiens)1624291 PMID:37283053RGDPMID:37283053

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Thumpd2Ratmethyltransferase activity enablesIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Thumpd2Ratprotein binding enablesISOTHUMPD2 (Homo sapiens)1624291UniProtKB:O76024 more ...RGDPMID:32814053 and PMID:34948388
Thumpd2RatRNA binding enablesIEAUniRule:UR0004005071600115GO_REF:0000104UniProtGO_REF:0000104
Thumpd2RatRNA binding enablesIEAInterPro:IPR0041141600115GO_REF:0000002InterProGO_REF:0000002
Thumpd2RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Thumpd2RattRNA (guanine) methyltransferase activity enablesIBAPANTHER:PTN000382878 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Thumpd2RatU6 snRNA (guanine-N(2))-methyltransferase activity enablesIEAUniProtKB:Q9BTF0 and ensembl:ENSP000004239331600115GO_REF:0000107EnsemblGO_REF:0000107
Thumpd2RatU6 snRNA (guanine-N(2))-methyltransferase activity enablesISOTHUMPD2 (Homo sapiens)1624291 PMID:37283053RGDPMID:37283053


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932  



Thumpd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8619,677,039 - 19,728,947 (+)NCBIGRCr8
mRatBN7.2613,924,742 - 13,976,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl613,924,765 - 13,976,657 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx614,228,394 - 14,280,284 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0614,551,389 - 14,596,793 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0614,041,656 - 14,093,548 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.063,743,080 - 3,794,512 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl63,743,074 - 3,794,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.063,710,777 - 3,762,198 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.463,974,995 - 4,026,884 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.163,974,998 - 4,026,884 (-)NCBI
Celera613,611,109 - 13,658,637 (+)NCBICelera
Cytogenetic Map6q12NCBI
THUMPD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38239,736,060 - 39,779,276 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl239,736,060 - 39,779,267 (-)EnsemblGRCh38hg38GRCh38
GRCh37239,963,200 - 40,006,416 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36239,816,949 - 39,859,881 (-)NCBINCBI36Build 36hg18NCBI36
Build 34239,875,095 - 39,918,028NCBI
Celera239,804,157 - 39,847,379 (-)NCBICelera
Cytogenetic Map2p22.1NCBI
HuRef239,702,624 - 39,745,816 (-)NCBIHuRef
CHM1_1239,893,491 - 39,936,707 (-)NCBICHM1_1
T2T-CHM13v2.0239,745,056 - 39,788,273 (-)NCBIT2T-CHM13v2.0
Thumpd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391781,331,676 - 81,372,542 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1781,333,761 - 81,372,511 (-)EnsemblGRCm39 Ensembl
GRCm381781,024,247 - 81,065,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1781,026,332 - 81,065,082 (-)EnsemblGRCm38mm10GRCm38
MGSCv371781,425,667 - 81,464,425 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361780,934,653 - 80,973,411 (-)NCBIMGSCv36mm8
Celera1785,358,226 - 85,398,858 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1751.04NCBI
Thumpd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554417,329,093 - 7,369,782 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554417,329,468 - 7,369,957 (-)NCBIChiLan1.0ChiLan1.0
THUMPD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21286,690,167 - 86,732,755 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A86,694,147 - 86,737,375 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A39,768,913 - 39,816,471 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A40,526,774 - 40,569,226 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A40,526,774 - 40,571,909 (-)Ensemblpanpan1.1panPan2
THUMPD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11731,701,025 - 31,738,451 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1731,701,475 - 31,738,478 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1731,460,906 - 31,498,263 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01732,359,635 - 32,397,274 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1732,359,660 - 32,397,265 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11731,580,931 - 31,618,257 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01731,650,259 - 31,687,785 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01731,864,590 - 31,902,483 (-)NCBIUU_Cfam_GSD_1.0
Thumpd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629240,140,558 - 40,182,653 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650811,569,170 - 11,611,609 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650811,569,195 - 11,611,264 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THUMPD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3100,557,016 - 100,597,671 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13100,557,168 - 100,597,664 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23106,694,190 - 106,734,643 (-)NCBISscrofa10.2Sscrofa10.2susScr3
THUMPD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11467,589,985 - 67,632,144 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604544,305,947 - 44,375,406 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thumpd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473821,237,709 - 21,287,551 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473821,238,535 - 21,287,491 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Thumpd2
325 total Variants

Predicted Target Of
Summary Value
Count of predictions:147
Count of miRNA genes:118
Interacting mature miRNAs:126
Transcripts:ENSRNOT00000011000
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)6796416721301982Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat

1 to 10 of 29 rows
RH130889  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2613,947,264 - 13,947,448 (-)MAPPERmRatBN7.2
Rnor_6.063,771,818 - 3,772,001NCBIRnor6.0
Rnor_5.063,739,515 - 3,739,698UniSTSRnor5.0
RGSC_v3.464,004,199 - 4,004,382UniSTSRGSC3.4
Celera613,633,564 - 13,633,747UniSTS
Cytogenetic Map6q12UniSTS
RH132120  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2613,976,412 - 13,976,562 (-)MAPPERmRatBN7.2
Rnor_6.063,743,175 - 3,743,324NCBIRnor6.0
Rnor_5.063,710,872 - 3,711,021UniSTSRnor5.0
RGSC_v3.463,975,090 - 3,975,239UniSTSRGSC3.4
Celera613,658,393 - 13,658,542UniSTS
Cytogenetic Map6q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000011000   ⟹   ENSRNOP00000011000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl613,924,765 - 13,976,657 (+)Ensembl
Rnor_6.0 Ensembl63,743,080 - 3,794,501 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084499   ⟹   ENSRNOP00000071513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl613,924,765 - 13,976,653 (+)Ensembl
Rnor_6.0 Ensembl63,743,084 - 3,794,501 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087891   ⟹   ENSRNOP00000075202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl613,924,765 - 13,976,653 (+)Ensembl
Rnor_6.0 Ensembl63,743,074 - 3,794,489 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100728   ⟹   ENSRNOP00000086376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl613,934,280 - 13,974,854 (+)Ensembl
RefSeq Acc Id: NM_001012108   ⟹   NP_001012108
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,060 - 19,728,944 (+)NCBI
mRatBN7.2613,924,765 - 13,976,654 (+)NCBI
Rnor_6.063,743,083 - 3,794,501 (-)NCBI
Rnor_5.063,710,777 - 3,762,198 (-)NCBI
RGSC_v3.463,974,995 - 4,026,884 (-)RGD
Celera613,611,109 - 13,658,634 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001163506   ⟹   NP_001156978
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,060 - 19,728,947 (+)NCBI
mRatBN7.2613,924,765 - 13,976,657 (+)NCBI
Rnor_6.063,743,080 - 3,794,501 (-)NCBI
Rnor_5.063,710,777 - 3,762,198 (-)NCBI
RGSC_v3.463,974,995 - 4,026,884 (-)RGD
Celera613,611,109 - 13,658,637 (+)RGD
Sequence:
RefSeq Acc Id: NM_001410276   ⟹   NP_001397205
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,060 - 19,728,944 (+)NCBI
mRatBN7.2613,924,765 - 13,976,654 (+)NCBI
RefSeq Acc Id: XM_006239673   ⟹   XP_006239735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,976,654 (+)NCBI
Rnor_6.063,743,083 - 3,794,512 (-)NCBI
Rnor_5.063,710,777 - 3,762,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239675   ⟹   XP_006239737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,976,173 (+)NCBI
Rnor_6.063,743,612 - 3,794,512 (-)NCBI
Rnor_5.063,710,777 - 3,762,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239677   ⟹   XP_006239739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,976,173 (+)NCBI
Rnor_6.063,743,612 - 3,794,512 (-)NCBI
Rnor_5.063,710,777 - 3,762,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764440   ⟹   XP_008762662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,039 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,976,183 (+)NCBI
Rnor_6.063,743,599 - 3,794,512 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594116   ⟹   XP_017449605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,972,933 (+)NCBI
Rnor_6.063,746,910 - 3,794,512 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112142   ⟹   XP_038968070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,976,173 (+)NCBI
RefSeq Acc Id: XM_039112143   ⟹   XP_038968071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,044 - 19,728,944 (+)NCBI
mRatBN7.2613,924,742 - 13,976,183 (+)NCBI
RefSeq Acc Id: XM_039112145   ⟹   XP_038968073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,723,197 (+)NCBI
mRatBN7.2613,924,742 - 13,970,951 (+)NCBI
RefSeq Acc Id: XM_063261827   ⟹   XP_063117897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,045 - 19,728,944 (+)NCBI
RefSeq Acc Id: XR_005505504
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8619,677,039 - 19,704,510 (+)NCBI
mRatBN7.2613,924,742 - 13,952,212 (+)NCBI
1 to 5 of 16 rows
1 to 5 of 16 rows
RefSeq Acc Id: NP_001156978   ⟸   NM_001163506
- Peptide Label: isoform 1
- UniProtKB: D4A475 (UniProtKB/TrEMBL),   A6H9P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001012108   ⟸   NM_001012108
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K0N2 (UniProtKB/TrEMBL),   Q5FVM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239735   ⟸   XM_006239673
- Peptide Label: isoform X1
- UniProtKB: A6H9P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239739   ⟸   XM_006239677
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K0N2 (UniProtKB/TrEMBL),   Q5FVM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239737   ⟸   XM_006239675
- Peptide Label: isoform X4
- Sequence:
Name Modeler Protein Id AA Range Protein Structure
AF-D4A475-F1-model_v2 AlphaFold D4A475 1-549 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694369
Promoter ID:EPDNEW_R4894
Type:multiple initiation site
Name:Thumpd2_1
Description:THUMP domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.063,794,502 - 3,794,562EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-38547 BioCyc
Ensembl Genes ENSRNOG00000008291 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011000 ENTREZGENE
  ENSRNOT00000011000.6 UniProtKB/TrEMBL
  ENSRNOT00000084499 ENTREZGENE
  ENSRNOT00000084499.2 UniProtKB/TrEMBL
  ENSRNOT00000087891 ENTREZGENE
  ENSRNOT00000087891.2 UniProtKB/TrEMBL
  ENSRNOT00000100728.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2130.30 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7324079 IMAGE-MGC_LOAD
InterPro RNA_methylase UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
  THUMP UniProtKB/TrEMBL
KEGG Report rno:313851 UniProtKB/TrEMBL
MGC_CLONE MGC:108999 IMAGE-MGC_LOAD
NCBI Gene 313851 ENTREZGENE
PANTHER THUMP DOMAIN-CONTAINING UniProtKB/TrEMBL
  THUMP DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam UPF0020 UniProtKB/TrEMBL
PhenoGen Thumpd2 PhenoGen
PROSITE THUMP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008291 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
  THUMP domain-like UniProtKB/TrEMBL
UniProt A0A0G2K0N2 ENTREZGENE
  A0A0G2KA02 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3I0 ENTREZGENE, UniProtKB/TrEMBL
  A6H9P7 ENTREZGENE, UniProtKB/TrEMBL
  D4A475 ENTREZGENE, UniProtKB/TrEMBL
  Q5FVM9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2K0N2 UniProtKB/TrEMBL
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Thumpd2  THUMP domain containing 2  Thumpd2_predicted  THUMP domain containing 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Thumpd2_predicted  THUMP domain containing 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED