Pgpep1 (pyroglutamyl-peptidase I) - Rat Genome Database

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Gene: Pgpep1 (pyroglutamyl-peptidase I) Rattus norvegicus
Analyze
Symbol: Pgpep1
Name: pyroglutamyl-peptidase I
RGD ID: 1303133
Description: Enables peptidase activity. Involved in protein catabolic process. Predicted to be located in cytosol. Orthologous to human PGPEP1 (pyroglutamyl-peptidase I); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 5-oxoprolyl-peptidase; PAP-I; PAPI; PGP-I; pyroglutamyl aminopeptidase I; pyroglutamyl-peptidase 1; pyrrolidone-carboxylate peptidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,804,408 - 18,817,466 (+)NCBIGRCr8
mRatBN7.21618,770,563 - 18,782,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,812,708 - 18,822,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,945,640 - 19,955,013 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,865,663 - 18,875,020 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,521,989 - 20,531,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,379,057 - 20,388,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,276,650 - 19,285,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,276,652 - 19,285,272 (+)NCBI
Celera1618,962,969 - 18,971,980 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgpep1RatMegalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1  ISOPGPEP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1ClinVarPMID:28492532
Pgpep1Ratprostate cancer  ISOPGPEP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVarPMID:23265383

1 to 20 of 86 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgpep1Rat(1->4)-beta-D-glucan multiple interactionsISOPgpep1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PGPEP1 mRNACTDPMID:36331819
Pgpep1Rat1,1-dichloroethene decreases expressionISOPgpep1 (Mus musculus)6480464vinylidene chloride results in decreased expression of PGPEP1 mRNACTDPMID:26682919
Pgpep1Rat17alpha-ethynylestradiol affects expressionISOPgpep1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of PGPEP1 mRNACTDPMID:17555576
Pgpep1Rat17beta-estradiol increases expressionISOPGPEP1 (Homo sapiens)6480464Estradiol results in increased expression of PGPEP1 mRNACTDPMID:23019147
Pgpep1Rat17beta-estradiol decreases expressionISOPGPEP1 (Homo sapiens)6480464Estradiol results in decreased expression of PGPEP1 mRNACTDPMID:31614463
Pgpep1Rat17beta-estradiol decreases expressionISOPgpep1 (Mus musculus)6480464Estradiol results in decreased expression of PGPEP1 mRNACTDPMID:39298647
Pgpep1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PGPEP1 mRNACTDPMID:32145629
Pgpep1Rat17beta-estradiol multiple interactionsISOPGPEP1 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of PGPEP1 mRNACTDPMID:30165855
Pgpep1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPgpep1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PGPEP1 mRNACTDPMID:21570461
Pgpep1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PGPEP1 mRNACTDPMID:33387578
Pgpep1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PGPEP1 mRNACTDPMID:34747641
Pgpep1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of PGPEP1 mRNACTDPMID:21346803
Pgpep1Rat3,3',4,4',5-pentachlorobiphenyl multiple interactionsEXP 6480464[3 more ...CTDPMID:30744511
Pgpep1Rat3,4,5,3',4',5'-Hexachlorobiphenyl multiple interactionsEXP 6480464[3 more ...CTDPMID:30744511
Pgpep1Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of PGPEP1 proteinCTDPMID:34915118
Pgpep1Rat4,4'-sulfonyldiphenol decreases expressionISOPgpep1 (Mus musculus)6480464bisphenol S results in decreased expression of PGPEP1 mRNACTDPMID:39298647
Pgpep1Rat4-hydroxyphenyl retinamide increases expressionISOPgpep1 (Mus musculus)6480464Fenretinide results in increased expression of PGPEP1 mRNACTDPMID:28973697
Pgpep1Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of PGPEP1 mRNACTDPMID:31881176
Pgpep1Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of PGPEP1 mRNACTDPMID:28959563
Pgpep1Rataflatoxin B1 decreases methylationISOPGPEP1 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PGPEP1 intronCTDPMID:30157460

1 to 20 of 86 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgpep1Ratpositive regulation of actin filament bundle assembly involved_inIBAMGI:97550 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pgpep1Ratprotein catabolic process  IDA 1303965 RGD 
Pgpep1Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Pgpep1Ratproteolysis involved_inIEAInterPro:IPR0008161600115GO_REF:0000002InterProGO_REF:0000002
Pgpep1Ratregulation of actin filament polymerization involved_inIBAMGI:97550 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgpep1Ratcytoplasm is_active_inIBAMGI:97549 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pgpep1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Pgpep1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Pgpep1Ratcytosol located_inIEAInterPro:IPR0008161600115GO_REF:0000002InterProGO_REF:0000002

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgpep1Ratactin binding enablesIBAPANTHER:PTN000358484 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pgpep1Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Pgpep1Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Pgpep1Ratpeptidase activity  IDA 1303965 RGD 
Pgpep1Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Pgpep1Ratprotein binding enablesISOPGPEP1 (Homo sapiens) and UniProtKB:Q9NXJ5-21624291UniProtKB:P29972 more ...RGDPMID:32296183
Pgpep1Ratpyroglutamyl-peptidase activity enablesIEAEC:3.4.19.31600115GO_REF:0000003UniProtGO_REF:0000003
Pgpep1Ratpyroglutamyl-peptidase activity enablesIEAInterPro:IPR0008161600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol. Abe K, etal., Biol Pharm Bull 2003 Nov;26(11):1528-33.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12450739   PMID:12477932   PMID:12953169   PMID:21329657  



Pgpep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,804,408 - 18,817,466 (+)NCBIGRCr8
mRatBN7.21618,770,563 - 18,782,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,812,708 - 18,822,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,945,640 - 19,955,013 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,865,663 - 18,875,020 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,521,989 - 20,531,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,379,057 - 20,388,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,276,650 - 19,285,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,276,652 - 19,285,272 (+)NCBI
Celera1618,962,969 - 18,971,980 (+)NCBICelera
Cytogenetic Map16p14NCBI
PGPEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,340,598 - 18,369,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,340,598 - 18,369,950 (+)EnsemblGRCh38hg38GRCh38
GRCh371918,451,408 - 18,480,760 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,312,408 - 18,341,763 (+)NCBINCBI36Build 36hg18NCBI36
Build 341918,312,449 - 18,338,156NCBI
Celera1918,353,176 - 18,382,554 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,015,122 - 18,044,514 (+)NCBIHuRef
CHM1_11918,451,669 - 18,480,994 (+)NCBICHM1_1
T2T-CHM13v2.01918,474,715 - 18,504,090 (+)NCBIT2T-CHM13v2.0
Pgpep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,099,086 - 71,113,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,099,085 - 71,113,038 (-)EnsemblGRCm39 Ensembl
GRCm38870,646,436 - 70,660,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,646,435 - 70,660,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv37873,173,010 - 73,183,580 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,578,100 - 73,588,670 (-)NCBIMGSCv36mm8
Celera873,205,873 - 73,216,439 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Pgpep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,138,393 - 3,148,331 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,138,393 - 3,148,321 (-)NCBIChiLan1.0ChiLan1.0
PGPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,201,216 - 23,230,535 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,209,543 - 22,255,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,819,337 - 17,848,683 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,792,335 - 18,819,031 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,792,341 - 18,812,697 (+)Ensemblpanpan1.1panPan2
PGPEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,666,250 - 44,695,823 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,578,117 - 44,611,462 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,149,943 - 45,182,925 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,149,948 - 45,181,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,387,041 - 44,420,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,797,168 - 44,830,716 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,072,579 - 45,106,156 (-)NCBIUU_Cfam_GSD_1.0
Pgpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,319,958 - 203,343,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,869,106 - 2,892,342 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,869,100 - 2,892,342 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGPEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,451,150 - 59,485,818 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,448,110 - 59,485,809 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PGPEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,818,743 - 16,837,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,818,643 - 16,836,949 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,503,594 - 2,532,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgpep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,610,335 - 1,622,955 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,610,325 - 1,623,189 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Pgpep1
56 total Variants

Predicted Target Of
Summary Value
Count of predictions:319
Count of miRNA genes:186
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000026597
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat

1 to 10 of 28 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000026597   ⟹   ENSRNOP00000026597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)Ensembl
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099711   ⟹   ENSRNOP00000095429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,772,911 - 18,783,478 (+)Ensembl
RefSeq Acc Id: NM_201988   ⟹   NP_973717
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,805,052 - 18,814,338 (+)NCBI
mRatBN7.21618,771,067 - 18,780,353 (+)NCBI
Rnor_6.01620,521,989 - 20,531,254 (+)NCBI
Rnor_5.01620,379,057 - 20,388,085 (+)NCBI
RGSC_v3.41619,276,650 - 19,285,828 (+)RGD
Celera1618,962,969 - 18,971,980 (+)RGD
Sequence:
RefSeq Acc Id: XM_039094320   ⟹   XP_038950248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,804,408 - 18,817,466 (+)NCBI
mRatBN7.21618,770,563 - 18,782,968 (+)NCBI
RefSeq Acc Id: XM_063275159   ⟹   XP_063131229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,804,639 - 18,817,466 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_973717 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950248 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131229 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98645 (Get FASTA)   NCBI Sequence Viewer  
  BAD01533 (Get FASTA)   NCBI Sequence Viewer  
  EDL90722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026597.5
  ENSRNOP00000026601
GenBank Protein Q76IC5 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_973717   ⟸   NM_201988
- UniProtKB: Q76IC5 (UniProtKB/Swiss-Prot),   A6KA15 (UniProtKB/TrEMBL),   A0A8I6B2L0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026597   ⟸   ENSRNOT00000026597
RefSeq Acc Id: XP_038950248   ⟸   XM_039094320
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000095429   ⟸   ENSRNOT00000099711
RefSeq Acc Id: XP_063131229   ⟸   XM_063275159
- Peptide Label: isoform X1

Name Modeler Protein Id AA Range Protein Structure
AF-Q76IC5-F1-model_v2 AlphaFold Q76IC5 1-209 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700021
Promoter ID:EPDNEW_R10544
Type:initiation region
Name:Pgpep1_1
Description:pyroglutamyl-peptidase I
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,521,969 - 20,522,029EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-11796 BioCyc
BioCyc Pathway PWY-7942 [5-oxo-L-proline metabolism] BioCyc
BioCyc Pathway Image PWY-7942 BioCyc
Ensembl Genes ENSRNOG00000019639 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000019657 ENTREZGENE
Ensembl Transcript ENSRNOT00000026597.7 UniProtKB/Swiss-Prot
  ENSRNOT00000026601 ENTREZGENE
Gene3D-CATH 3.40.630.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7108516 IMAGE-MGC_LOAD
InterPro Peptidase_C15 UniProtKB/Swiss-Prot
  Peptidase_C15-like UniProtKB/Swiss-Prot
  Peptidase_C15-like_sf UniProtKB/Swiss-Prot
  PGPEP1_Cys_AS UniProtKB/Swiss-Prot
  PGPEP1_Glu_AS UniProtKB/Swiss-Prot
KEGG Report rno:290648 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112578 IMAGE-MGC_LOAD
NCBI Gene 290648 ENTREZGENE
PANTHER PTHR23402 UniProtKB/Swiss-Prot
  PTHR23402:SF16 UniProtKB/Swiss-Prot
Pfam Peptidase_C15 UniProtKB/Swiss-Prot
PhenoGen Pgpep1 PhenoGen
PIRSF Prld-crbxl_pptds UniProtKB/Swiss-Prot
PRINTS PYROGLUPTASE UniProtKB/Swiss-Prot
PROSITE PYRASE_CYS UniProtKB/Swiss-Prot
  PYRASE_GLU UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019639 RatGTEx
  ENSRNOG00000019657 RatGTEx
Superfamily-SCOP SSF53182 UniProtKB/Swiss-Prot
UniProt A0A8I6B2L0 ENTREZGENE, UniProtKB/TrEMBL
  A6KA15 ENTREZGENE, UniProtKB/TrEMBL
  F7FNJ2_RAT UniProtKB/TrEMBL
  PGPI_RAT UniProtKB/Swiss-Prot, ENTREZGENE
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Pgpep1  pyroglutamyl-peptidase I      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Pgpep1  pyroglutamyl-peptidase I      Symbol and Name status set to provisional 70820 PROVISIONAL