Casp8ap2 (caspase 8 associated protein 2) - Rat Genome Database

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Gene: Casp8ap2 (caspase 8 associated protein 2) Chinchilla lanigera
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Symbol: Casp8ap2
Name: caspase 8 associated protein 2
RGD ID: 8987547
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activator activity involved in apoptotic process (ortholog); identical protein binding (ortholog); protease binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); Fas signaling pathway (ortholog); PARTICIPATES IN aldosterone signaling pathway; FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CASP8-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541116,535,646 - 16,568,139 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  

Cellular Component

  

Molecular Function
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp8ap2Chinchillacysteine-type endopeptidase activator activity involved in apoptotic process enablesISOCasp8ap2 (Mus musculus)9068941 PMID:10235259MGIPMID:10235259
Casp8ap2Chinchillaidentical protein binding enablesISOCasp8ap2 (Mus musculus)9068941 PMID:10235259MGIPMID:10235259
Casp8ap2Chinchillaprotease binding enablesISOUniProtKB:Q147909068941 PMID:17245429UniProtPMID:17245429
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:O15350-19068941 PMID:21725362IntActPMID:21725362
Casp8ap2Chinchillaprotein binding enablesISOPR:Q61160 more ...9068941 PMID:10235259MGIPMID:10235259
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:P41227 and UniProtKB:P562799068941 PMID:32296183IntActPMID:32296183
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:P23497 and UniProtKB:Q147909068941 PMID:17245429IntActPMID:17245429
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:P234979068941 PMID:17245429IntActPMID:17245429
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:Q610269068941 PMID:12477726UniProtPMID:12477726
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:Q9Y6Q99068941 PMID:15698540UniProtPMID:15698540
Casp8ap2Chinchillaprotein binding enablesISOUniProtKB:O759259068941 PMID:21338522IntActPMID:21338522
Casp8ap2ChinchillaSUMO polymer binding enablesISOCASP8AP2 (Homo sapiens)9068941 PMID:23086935UniProtPMID:23086935
Casp8ap2Chinchillatranscription corepressor activity enablesISOCASP8AP2 (Homo sapiens)9068941 PMID:12477726UniProtPMID:12477726
1 to 13 of 13 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp8ap2Chinchillaaldosterone signaling pathway   ISOCASP8AP2 (Homo sapiens)9068941 RGDPMID:21784126 and REF_RGD_ID:7421504

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:30032202  



Casp8ap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541116,535,646 - 16,568,139 (-)NCBIChiLan1.0ChiLan1.0
CASP8AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,829,880 - 89,874,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,829,894 - 89,874,436 (+)EnsemblGRCh38hg38GRCh38
GRCh37690,539,599 - 90,584,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,596,379 - 90,640,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 34690,596,378 - 90,640,875NCBI
Celera690,958,564 - 91,004,713 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,756,992 - 87,803,539 (+)NCBIHuRef
CHM1_1690,637,186 - 90,681,833 (+)NCBICHM1_1
T2T-CHM13v2.0691,029,094 - 91,086,157 (+)NCBIT2T-CHM13v2.0
Casp8ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,615,462 - 32,653,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm39 Ensembl
GRCm38432,615,470 - 32,653,271 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,702,448 - 32,740,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,944,126 - 32,981,873 (+)NCBIMGSCv36mm8
Celera432,362,733 - 32,400,576 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.27NCBI
Casp8ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,809,366 - 51,848,633 (+)NCBIGRCr8
mRatBN7.2547,014,501 - 47,052,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,014,667 - 47,052,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,156,788 - 49,194,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,755,948 - 50,793,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,701,113 - 50,738,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,853,699 - 47,891,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,853,818 - 47,891,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,451,775 - 52,489,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,920,175 - 48,958,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1548,928,473 - 49,096,830 (+)NCBI
Celera545,775,811 - 45,813,420 (+)NCBICelera
Cytogenetic Map5q21NCBI
CASP8AP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,811,413 - 107,860,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,707,152 - 87,754,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,979,710 - 91,026,770 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,996,127 - 91,023,757 (+)Ensemblpanpan1.1panPan2
CASP8AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11249,040,069 - 49,077,418 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1249,039,411 - 49,077,688 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,847,072 - 48,884,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,849,389 - 49,886,726 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,849,439 - 49,884,151 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11249,164,550 - 49,201,631 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01249,065,265 - 49,102,374 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01249,257,627 - 49,294,727 (+)NCBIUU_Cfam_GSD_1.0
Casp8ap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494684,022,998 - 84,049,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,420,920 - 2,447,986 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,420,924 - 2,447,634 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP8AP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,835,145 - 57,862,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,834,251 - 57,864,837 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,689,689 - 64,811,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CASP8AP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,586,857 - 14,632,384 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,586,929 - 14,632,362 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040190,973,325 - 191,019,815 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp8ap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247994,302,738 - 4,353,211 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Acc Id: XM_005377760   ⟹   XP_005377817
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541116,536,158 - 16,568,139 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005377761   ⟹   XP_005377818
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541116,535,646 - 16,568,139 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510890   ⟹   XP_013366344
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541116,536,158 - 16,568,132 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510891   ⟹   XP_013366345
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541116,536,158 - 16,568,139 (-)NCBI
Sequence:
Protein RefSeqs XP_005377817 (Get FASTA)   NCBI Sequence Viewer  
  XP_005377818 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366344 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366345 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017311.1
  ENSCLAP00000021702.1
RefSeq Acc Id: XP_005377818   ⟸   XM_005377761
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VTJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005377817   ⟸   XM_005377760
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VTJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366345   ⟸   XM_013510891
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VTJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366344   ⟸   XM_013510890
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VTJ5 (UniProtKB/TrEMBL)
- Sequence:



1 to 12 of 12 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000011885 UniProtKB/TrEMBL
  ENSCLAG00000014853 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017480.1 UniProtKB/TrEMBL
  ENSCLAT00000021905.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro FLASH UniProtKB/TrEMBL
NCBI Gene Casp8ap2 ENTREZGENE
PANTHER CASP8-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  PTHR15489 UniProtKB/TrEMBL
Pfam Myb_DNA-binding_7 UniProtKB/TrEMBL
UniProt A0A8C2VTJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YTA3_CHILA UniProtKB/TrEMBL
1 to 12 of 12 rows