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Gene: Lipm (lipase family member M) Chinchilla lanigera

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Symbol:

Lipm

Name:

lipase family member M

RGD ID:

8936504

Description:

ASSOCIATED WITH autoimmune lymphoproliferative syndrome (ortholog); PTEN hamartoma tumor syndrome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lipase member M; lipase, family member M

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LIPM (lipase family member M)	NCBI	Ortholog
Mus musculus (house mouse):	Lipm (lipase, family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Lipm (lipase, family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LIPM (lipase family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LIPM (lipase family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101956034 (lipase member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LIPM (lipase family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LIPM (lipase family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lipm (lipase family member M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	4,150,780 - 4,182,131 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	4,150,780 - 4,170,912 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune lymphoproliferative syndrome (ISO)

PTEN hamartoma tumor syndrome (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Lipm
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	4,150,780 - 4,182,131 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	4,150,780 - 4,170,912 (-)	NCBI	ChiLan1.0	ChiLan1.0

LIPM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	88,802,730 - 88,820,546 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	88,802,730 - 88,820,546 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	90,562,487 - 90,580,303 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	90,552,467 - 90,570,238 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	84,309,321 - 84,327,123 (+)	NCBI		Celera
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	84,197,174 - 84,214,974 (+)	NCBI		HuRef
CHM1_1	10	90,844,543 - 90,862,358 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	89,686,676 - 89,704,478 (+)	NCBI		T2T-CHM13v2.0

Lipm
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	34,078,343 - 34,100,087 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	34,078,333 - 34,100,087 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	34,100,943 - 34,122,687 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	34,100,933 - 34,122,687 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	34,175,433 - 34,197,177 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
Celera	19	34,877,668 - 34,899,413 (+)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	29.32	NCBI

Lipm
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	241,031,382 - 241,050,796 (+)	NCBI		GRCr8
mRatBN7.2	1	231,618,145 - 231,637,599 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	231,618,284 - 231,637,410 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	252,409,232 - 252,428,567 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	252,409,268 - 252,428,774 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	259,632,811 - 259,652,171 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	237,964,915 - 237,983,389 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	238,128,716 - 238,148,049 (+)	NCBI
Celera	1	228,732,079 - 228,751,382 (+)	NCBI		Celera
Cytogenetic Map	1	q52	NCBI

LIPM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	100,821,869 - 100,840,813 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	100,827,184 - 100,844,992 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	85,528,337 - 85,547,789 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	89,031,764 - 89,049,607 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	89,031,764 - 89,049,607 (+)	Ensembl	panpan1.1		panPan2

LIPM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	38,608,237 - 38,622,521 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	38,424,809 - 38,431,964 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	40,192,941 - 40,207,203 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	40,192,152 - 40,207,050 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	38,062,609 - 38,077,260 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	37,628,265 - 37,642,691 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	38,898,137 - 38,912,673 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101956034
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	78,380,202 - 78,393,613 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936735	399,584 - 418,264 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936735	399,567 - 418,264 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LIPM
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	100,726,480 - 100,748,300 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	100,716,038 - 100,748,916 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	109,700,870 - 109,732,335 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LIPM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	82,212,905 - 82,243,055 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	82,224,603 - 82,242,574 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	42,904,368 - 42,923,513 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lipm
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624791	15,097,419 - 15,117,158 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624791	15,097,263 - 15,119,135 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005385861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01025310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCC01000396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000013555 ⟹ ENSCLAP00000013402

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955425	4,150,780 - 4,170,920 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000013556 ⟹ ENSCLAP00000013403

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955425	4,151,438 - 4,182,131 (-)	Ensembl

RefSeq Acc Id:

XM_005385861 ⟹ XP_005385918

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955425	4,150,780 - 4,170,912 (-)	NCBI

Sequence:

show sequence

CAGAGCTTACTTGGTATTCTTCCATTCCTATCAGCTAAGCTTCCTTAATGTGCTTCAGAACTGA
GGGAAGAAATAGAAGCTAGAAAATATGTAAACAAGTTTTAAACCTACAGATTCTTCTTCTGCCT
TCAGATGTAGTTATTGTGTTGTCAGGGGAAAATAAATGCAGATGTTGGACCATGTCAGAAATCT
TGTCAACAGCCTGGATTGTTTCACACAGAGTGGAGATGTGGCTTCTGATTCTGGTCGCGTATTT
GCTTCAAAGAAATGTGAATTCAGGACATTTGCCAACTAAAGCTGTGGACCCTGAAGCATTCATG
AACATTAGTGAAATCATCCAGCATAAAGGCTACCCCTGTGAAGAGTATGAAGTTACAACGGAAG
ATGGGTATATCCTTTCTGTGAACAGAATTCCTCAAGGCCTAGCACAGCCTCAGAAGAAAGGTCC
CAGGCCAGTGGTGCTCCTGCAGCACGGTCTGCTTGGTGACGCCAGCAACTGGATTTCTAACCTG
CCCAACAATAGCCTGGGCTTCATCCTGGCAGATGCTGGTGTTGATGTGTGGCTGGGGAACAGCA
GGGGAAACACCTGGTCTCGGAAACACAAGACCCTCTCCATAGACCAAGATGAGTTCTGGGCTTT
CAGTTATGATGAGATGGCTAGGTTTGACCTTCCTGCAGTGATAAACTTTATTTTGCAGAAAACG
GGCCAGGAAAAGATCTATTACGTCGGCTATTCACAGGGCACAACCATGGGCTTTATTGCATTTT
CCACAATGCCAGAGCTGGCTCAGAAAATCAAAATGTATTTTGCTTTGGCCCCTATAGCCACTGT
TAAATATGCAAAAAGCCCTGGGACCAAATTTTTATTGCTGCCCGATATGATGATCAAGGGATTG
TTTGGCAGGCAAGAGTTTCTGTACCAGACGCGATTTTTCAGGCAGTTTGCTATTTACCTTTGTG
GCCAGATGATTCTTGATCAGATTTGTAGCAATATCATCTTACTAATGGGAGGATTTAACACGAA
CAATATGAACATGAGCCGAGCAAATGTGTATGTTGCCCATTCTCCTGCTGGGACATCTGTGCAG
AACATTCTACATTGGAGCCAGGCAGTGAATTCTGGGGAACTCCGAGCATTTGACTGGGGGAGTG
AGACCAAGAATCTGGAGAAAGGCAATCACCCAACTCCTTTAAGGTACAATGTTCGAGATATGAT
GGTCCCGACAGCGATGTGGTCAGGAGGTCAGGATTGGCTTTCAAATCCAGAAGATGTGAAAACA
CTGCTCTCTGAGGTGACCAACCTCATCTATCACAAGAACATTCCTGAGTGGGCTCACATAGACT
TCATCTGGGGGCTGGACGCCCCCCACCGGGTGTACAATGAAATCATACATTTGATGAAGCAGGA
GGAGGCTGACCTGTCCCAGGAGACCTGCAAGGTCTTACTGTAAGACTTCTGATACTGACAAGAC
TTAGGAGCAACCTTCTGGAAGACGGAGCTAGGACCAGGAACAGCGTAGAGGATTTTAGAATTTT
TCAGAAGGGAAAACCTATTTTATCTTTCAACAGGAAGTCAGAGATAACAGTTATATTTTCCTTC
AGTTTCTACATTTGGCACTAATACTCAGATTTACAGTTTTTTTTCAGTTAGTTAAACTAAAGTA
AGAGTAAATATGGGTTTCCTGTGCTATCATGTCTTCTACCGTTTTGAAAGTTAATTTTCACCTG
ACAGCCAGAAAGTACCTAGATGTTCACTACATCATTTAGATAAACCACCCTCATACGTTTATTT
TTTCTAAAGCCGTATTTTTGGAGGAGTAAAATAAAATGACATATTGGAGTAGATATTGAGGTCA
AAAAATCTCTAGATTGTTGTTGGTTTTGAAAACATGATCTGGACAGTTTTGCCTTGTTGCCATG
GAGTCAGGATACTACCTACCTCAGGAAGCCAATTGGCTTTAGCAACAATGAAAAAATCACTATG
TGGCACAGAGGAATACATGTTAAACATTCTCAGAATACGGCCAAGTTTTAGAGTTGAATCACAG
AGAAGATACTTTGGTAGGATATTCGCGAGTTTCCCAATAAATACGTTATGCATTGAATGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005385918	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000013402
	ENSCLAP00000013402.1
	ENSCLAP00000013403.1

RefSeq Acc Id:

XP_005385918 ⟸ XM_005385861

- UniProtKB:

A0A8C2VC69 (UniProtKB/TrEMBL), A0A8C2VC75 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSEILSTAWIVSHRVEMWLLILVAYLLQRNVNSGHLPTKAVDPEAFMNISEIIQHKGYPCEEYE
VTTEDGYILSVNRIPQGLAQPQKKGPRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGVDVW
LGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQEKIYYVGYSQGTTMG
FIAFSTMPELAQKIKMYFALAPIATVKYAKSPGTKFLLLPDMMIKGLFGRQEFLYQTRFFRQFA
IYLCGQMILDQICSNIILLMGGFNTNNMNMSRANVYVAHSPAGTSVQNILHWSQAVNSGELRAF
DWGSETKNLEKGNHPTPLRYNVRDMMVPTAMWSGGQDWLSNPEDVKTLLSEVTNLIYHKNIPEW
AHIDFIWGLDAPHRVYNEIIHLMKQEEADLSQETCKVLL

hide sequence

Ensembl Acc Id:

ENSCLAP00000013402 ⟸ ENSCLAT00000013555

Ensembl Acc Id:

ENSCLAP00000013403 ⟸ ENSCLAT00000013556

Protein Domains

AB hydrolase-1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009261	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000013555	ENTREZGENE
	ENSCLAT00000013555.1	UniProtKB/TrEMBL
	ENSCLAT00000013556.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	AB_hydrolase_1	UniProtKB/TrEMBL
	Lipase_euk	UniProtKB/TrEMBL
NCBI Gene	Lipm	ENTREZGENE
PANTHER	LIPASE MEMBER M	UniProtKB/TrEMBL
	LYSOSOMAL ACID LIPASE-RELATED	UniProtKB/TrEMBL
Pfam	Abhydrolase_1	UniProtKB/TrEMBL
PIRSF	Steryl_ester_lip	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	A0A8C2VC69	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VC75	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Lipm	lipase family member M		lipase, family member M	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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