Lipm (lipase family member M) - Rat Genome Database

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Gene: Lipm (lipase family member M) Heterocephalus glaber
Analyze
Symbol: Lipm
Name: lipase family member M
RGD ID: 18930938
Description: ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on ester bonds (inferred); INVOLVED IN lipid catabolic process (inferred); ASSOCIATED WITH autoimmune lymphoproliferative syndrome (ortholog); PTEN hamartoma tumor syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Lipase member M
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479115,097,419 - 15,117,158 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479115,097,263 - 15,119,135 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Lipm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479115,097,419 - 15,117,158 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479115,097,263 - 15,119,135 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LIPM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381088,802,730 - 88,820,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1088,802,730 - 88,820,546 (+)EnsemblGRCh38hg38GRCh38
GRCh371090,562,487 - 90,580,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,552,467 - 90,570,238 (+)NCBINCBI36Build 36hg18NCBI36
Celera1084,309,321 - 84,327,123 (+)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1084,197,174 - 84,214,974 (+)NCBIHuRef
CHM1_11090,844,543 - 90,862,358 (+)NCBICHM1_1
T2T-CHM13v2.01089,686,676 - 89,704,478 (+)NCBIT2T-CHM13v2.0
Lipm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,078,343 - 34,100,087 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,078,333 - 34,100,087 (+)EnsemblGRCm39 Ensembl
GRCm381934,100,943 - 34,122,687 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,100,933 - 34,122,687 (+)EnsemblGRCm38mm10GRCm38
MGSCv371934,175,433 - 34,197,177 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1934,877,668 - 34,899,413 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.32NCBI
Lipm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,031,382 - 241,050,796 (+)NCBIGRCr8
mRatBN7.21231,618,145 - 231,637,599 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1231,618,284 - 231,637,410 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01252,409,232 - 252,428,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,409,268 - 252,428,774 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01259,632,811 - 259,652,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,964,915 - 237,983,389 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11238,128,716 - 238,148,049 (+)NCBI
Celera1228,732,079 - 228,751,382 (+)NCBICelera
Cytogenetic Map1q52NCBI
Lipm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554254,150,780 - 4,182,131 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554254,150,780 - 4,170,912 (-)NCBIChiLan1.0ChiLan1.0
LIPM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28100,821,869 - 100,840,813 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110100,827,184 - 100,844,992 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01085,528,337 - 85,547,789 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11089,031,764 - 89,049,607 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1089,031,764 - 89,049,607 (+)Ensemblpanpan1.1panPan2
LIPM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12638,608,237 - 38,622,521 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2638,424,809 - 38,431,964 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02640,192,941 - 40,207,203 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2640,192,152 - 40,207,050 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12638,062,609 - 38,077,260 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02637,628,265 - 37,642,691 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02638,898,137 - 38,912,673 (+)NCBIUU_Cfam_GSD_1.0
LOC101956034
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721378,380,202 - 78,393,613 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936735399,584 - 418,264 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936735399,567 - 418,264 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIPM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14100,726,480 - 100,748,300 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114100,716,038 - 100,748,916 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214109,700,870 - 109,732,335 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIPM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1982,212,905 - 82,243,055 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl982,224,603 - 82,242,574 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604842,904,368 - 42,923,513 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000008472   ⟹   ENSHGLP00000008383
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479115,097,419 - 15,117,158 (+)Ensembl
RefSeq Acc Id: XM_004858365   ⟹   XP_004858422
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479115,097,263 - 15,119,135 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004858422 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB12413 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008383
  ENSHGLP00000057326
RefSeq Acc Id: XP_004858422   ⟸   XM_004858365
- UniProtKB: G5BT02 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000008383   ⟸   ENSHGLT00000008472


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006060 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000008472 ENTREZGENE
  ENSHGLT00000044701 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  Lipase_euk UniProtKB/TrEMBL
KEGG Report hgl:101704038 UniProtKB/TrEMBL
NCBI Gene Lipm ENTREZGENE
PANTHER LYSOSOMAL ACID LIPASE-RELATED UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PIRSF Steryl_ester_lip UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt G5BT02 ENTREZGENE, UniProtKB/TrEMBL