Rtn4rl2 (reticulon 4 receptor like 2)

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Gene: Rtn4rl2 (reticulon 4 receptor like 2) Chinchilla lanigera

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Symbol:

Rtn4rl2

Name:

reticulon 4 receptor like 2

RGD ID:

8853203

Description:

ENCODES a protein that exhibits signaling receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); corpus callosum development (ortholog); negative regulation of neuron projection development (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); external side of plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

reticulon 4 receptor-like 2; reticulon-4 receptor-like 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955511	2,463,006 - 2,474,045 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface receptor signaling pathway (ISO)

corpus callosum development (ISO)

negative regulation of neuron projection development (ISO)

Cellular Component

axon (ISO)

cell surface (ISO)

external side of plasma membrane (ISO)

membrane raft (ISO)

neuron projection (ISO)

perikaryon (ISO)

plasma membrane (ISO)

Molecular Function

protein binding (ISO)

signaling receptor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Rtn4rl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955511	2,463,006 - 2,474,045 (+)	NCBI	ChiLan1.0	ChiLan1.0

RTN4RL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	57,460,528 - 57,477,534 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	57,460,528 - 57,477,534 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	57,228,001 - 57,245,007 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	56,984,915 - 57,000,960 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	56,984,914 - 57,000,960	NCBI
Celera	11	54,584,904 - 54,600,951 (+)	NCBI		Celera
Cytogenetic Map	11	q12.1	NCBI
HuRef	11	53,577,332 - 53,593,249 (+)	NCBI		HuRef
CHM1_1	11	57,094,644 - 57,110,689 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	57,410,743 - 57,427,752 (+)	NCBI		T2T-CHM13v2.0

Rtn4rl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	84,701,653 - 84,718,985 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	84,702,268 - 84,717,054 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	84,871,297 - 84,888,641 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	84,871,924 - 84,886,710 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	84,712,103 - 84,726,849 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	84,672,785 - 84,687,531 (-)	NCBI		MGSCv36	mm8
Celera	2	86,470,110 - 86,484,840 (-)	NCBI		Celera
Cytogenetic Map	2	D	NCBI
cM Map	2	49.45	NCBI

Rtn4rl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	90,361,234 - 90,377,775 (-)	NCBI		GRCr8
mRatBN7.2	3	69,954,557 - 69,971,108 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	69,955,169 - 69,971,488 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	73,336,652 - 73,353,243 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	81,935,323 - 81,951,912 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	79,693,746 - 79,710,228 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	72,272,814 - 72,289,310 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	72,273,424 - 72,289,310 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	78,792,727 - 78,809,760 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	68,098,435 - 68,113,874 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	67,994,806 - 68,010,246 (-)	NCBI
Celera	3	69,310,032 - 69,324,497 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

RTN4RL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	58,616,869 - 58,633,957 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	59,633,959 - 59,650,954 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	52,701,378 - 52,718,385 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	56,174,245 - 56,190,508 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	56,174,358 - 56,190,410 (+)	Ensembl	panpan1.1		panPan2

RTN4RL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	38,681,742 - 38,696,661 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	38,689,025 - 38,690,234 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	38,228,356 - 38,242,033 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	39,364,300 - 39,377,991 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	39,363,300 - 39,378,515 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	38,946,827 - 38,960,492 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	38,520,507 - 38,534,147 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	39,150,891 - 39,164,583 (-)	NCBI		UU_Cfam_GSD_1.0

Rtn4rl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	14,902,687 - 14,936,583 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	5,016,499 - 5,031,676 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	5,016,521 - 5,050,405 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RTN4RL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	13,442,349 - 13,458,875 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	13,442,716 - 13,459,063 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RTN4RL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	15,757,790 - 15,775,804 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	113,106,708 - 113,123,856 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rtn4rl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624864	3,152,958 - 3,186,043 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013506377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01066405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01066406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01066407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01066408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01148153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013506377 ⟹ XP_013361831

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955511	2,463,006 - 2,474,045 (+)	NCBI

Sequence:

show sequence

CCGGCCTCGCCGCGCGGGGACCCCCTGCCCCCCGGCCCCGCGGGCCCCGCCGTCCGGCCGCGCG
CCGTGGGAGCGCGTGGGAGCCCCCGCCTCGAGAGTCGGGGCAAGATGCTGCCCGGGCGGCGGCG
CCGGCTGCAAGGTCCCCCCGCCTGCCTGCTGCTGCTGCTGGCCCTGCCCGCCGCGGCGCCCAGC
TGCCCCATGCTGTGCACCTGCTACGCGTCCCCGCCCACCGTGAGCTGCCAGGCCAACAACTTCT
CGTCCGTGCCGCTGTCCCTGCCGCCCGGCACGCAGCGCCTCTTCCTGCAGAACAACCTCATCCG
CACGCTGCGGCCCGGCACCTTCGGGCCCAACCTGCTCACGCTGTGGCTCTTTGCCAACAACCTC
TCCACCATCTACCCGGGCACCTTCCGCCACCTGCAGGCCCTGGAGGAGCTGGACCTGGGCGACA
ACCGGCACCTGCGCTCGCTGGAGCCCGACACCTTCCAGGGCCTGGAGCGCCTGCAGTCGCTGCA
CCTGTACCGCTGCCAGCTCAGCAGCCTGCCCGGCACCATCTTCCGCGGCCTGGTCAGCCTGCAG
TACCTCTACCTCCAGGACAACAGCCTGCTGCACCTCCAGGTGAGCGCCGTCCGCCCCGGGGCCC
GGAGCCTTGCTGCCTCAGCCTCCCCGGCCCTCGCTTCCCTGCTCCTTTCCTGGCGACCGGTGGT
TCGCTGTGCTGGTGGAAGGCTGCTCCTCCGAGCCCGTTTCCTCATCCGTCAGCTACGGATAACG
AAAGCCCTGCCTGCCCCGGGGGCTGAGGGGGACCCAGCCGTCGCCCCGTGCCAAGTAGGCAATG
CAGGCAAGCAGGAGCCGGCCTCAGGCACCGGCTCCACCCCCAGCGTGAAGGGCTGTGGGCACCC
TGGCCGGGCAGCGGAAGGAGGTAGCGGGGCTGTGAGCACCGGGCAGGCGAGGGACTCGTGCGCA
GGGCTGCGACCGAGGCAAGCGTGTGCCCCACCCGCTGCAGCCGGCCTGGCCGTCAGGCGCCGCT
CGGAGGAGGTGACAGGGAGGCGGCTGTCAGTCACCGGCGTTGGCTGCATGGCCCGCAGCTGCCC
CGCCGGTGCCCAGCTCTGGGTGGCCACTGTAGTTATGGTTCTCACAGGCTCAGCTAAGGCAGGC
AGAGGCTACCAGCTGTCAGGGCCACAGCCCAGCCTGGCCACGGCTCTGCTTCTGAGGGCCACGG
CCTGGTGGCCGCTGGCCCTGTCCCTCCCACCGGCCTCTCCTGAGAGCCAAACGGGGCCAGCAGG
CCAGCGGGTCGGGTTGCCATGCATCTTTAATGCGGCCGGCCCGTCAGATGTTCCGAAACCCGAG
CGGCGCGGGGCGCCGGCCCTGCACCGTGTCCTTGCGCGCCCGCCCGTGGCCTGGGGACAGCAGG
CGGCCGGCAGCCGGGACAGCTACCCAGGGCCTCCCGGGGGGCCTGTTATCCCGCTGACCGGCTT
TAACCCATGCGACCCGGTGGCCACGATCCCTGCAGCCGCGCAGACCTCGGTGGAGCGCGGGGGG
CGCACGCCAGGGCTGCGCACTGCGCAAAGGGGTGTCAGCGAGCCCGCGCCTGCCCGCCCCGCTC
GCTGGAGGAGACGGGAGGGGGGCTTCTCCCGGGAGACTCGGGGCGTCGAAATTCCTCGTTCCTC
ATCCTCTGGCCCCCGCACCCCTCCTCCTCCCAGCCATCTGTTCCCCTCGGCAGCGCCGCGACAA
ACACGGCTCCACGCTTCCGCCGCCCGCCCTCCCCACTCCCGGCCCCAGGGTGGGAGCAAGCAAA
GGCCTCGTCCCGCCGGGCTCCAGCCGGGCGGGCGGGGCGCGGACTCGGTGCCGGAGCCGGGTCG
TGGGGTCCCCCTCTCCCCGCAGCGCCACCTGCCGGACGCTCTGCCCCCCAGCTGCTGGTCACGC
GTCCCAGACCGCGGGGACAGCCAGGGACAGACAGGGCCCGCACGCCCGGCCAGCGGCCGCCGAG
TCAGCGGGAGTCGCGGGTGA

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Protein Sequences


Protein RefSeqs	XP_013361831	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013361831 ⟸ XM_013506377

- Sequence:

show sequence

MLPGRRRRLQGPPACLLLLLALPAAAPSCPMLCTCYASPPTVSCQANNFSSVPLSLPPGTQRLF
LQNNLIRTLRPGTFGPNLLTLWLFANNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGL
ERLQSLHLYRCQLSSLPGTIFRGLVSLQYLYLQDNSLLHLQVSAVRPGARSLAASASPALASLL
LSWRPVVRCAGGRLLLRARFLIRQLRITKALPAPGAEGDPAVAPCQVGNAGKQEPASGTGSTPS
VKGCGHPGRAAEGGSGAVSTGQARDSCAGLRPRQACAPPAAAGLAVRRRSEEVTGRRLSVTGVG
CMARSCPAGAQLWVATVVMVLTGSAKAGRGYQLSGPQPSLATALLLRATAWWPLALSLPPASPE
SQTGPAGQRVGLPCIFNAAGPSDVPKPERRGAPALHRVLARPPVAWGQQAAGSRDSYPGPPGGP
VIPLTGFNPCDPVATIPAAAQTSVERGGRTPGLRTAQRGVSEPAPARPARWRRREGGFSRETRG
VEIPRSSSSGPRTPPPPSHLFPSAAPRQTRLHASAARPPHSRPQGGSKQRPRPAGLQPGGRGAD
SVPEPGRGVPLSPQRHLPDALPPSCWSRVPDRGDSQGQTGPARPASGRRVSGSRG

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	LOC102029773	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-02-28	Rtn4rl2	reticulon 4 receptor like 2		reticulon 4 receptor-like 2	Symbol and/or name change	5135510	APPROVED
2015-08-25	Rtn4rl2	reticulon 4 receptor-like 2	LOC102029773	uncharacterized LOC102029773	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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