Fem1a (fem-1 homolog A) - Rat Genome Database

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Gene: Fem1a (fem-1 homolog A) Chinchilla lanigera
Analyze
Symbol: Fem1a
Name: fem-1 homolog A
RGD ID: 8826406
Description: ENCODES a protein that exhibits EP4 subtype prostaglandin E2 receptor binding (ortholog); molecular adaptor activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of inflammatory response (ortholog); negative regulation of MAP kinase activity (ortholog); positive regulation of inflammatory response (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fem-1 homolog a (C. elegans)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,215,284 - 4,217,230 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,214,250 - 4,217,313 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Fem1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,215,284 - 4,217,230 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,214,250 - 4,217,313 (-)NCBIChiLan1.0ChiLan1.0
FEM1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,791,734 - 4,801,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,791,734 - 4,801,273 (+)EnsemblGRCh38hg38GRCh38
GRCh37194,791,746 - 4,801,285 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,742,728 - 4,746,571 (+)NCBINCBI36Build 36hg18NCBI36
Build 34194,742,769 - 4,746,567NCBI
Celera194,729,623 - 4,733,477 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,553,385 - 4,557,238 (+)NCBIHuRef
CHM1_1194,791,252 - 4,795,104 (+)NCBICHM1_1
T2T-CHM13v2.0194,777,196 - 4,786,749 (+)NCBIT2T-CHM13v2.0
Fem1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,563,793 - 56,570,608 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,563,810 - 56,570,610 (+)EnsemblGRCm39 Ensembl
GRCm381756,256,793 - 56,263,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,256,810 - 56,263,610 (+)EnsemblGRCm38mm10GRCm38
MGSCv371756,396,216 - 56,403,031 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,890,531 - 55,894,784 (+)NCBIMGSCv36mm8
Celera1760,359,868 - 60,366,683 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.24NCBI
Fem1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,178,857 - 1,181,063 (+)NCBIGRCr8
mRatBN7.291,091,695 - 1,093,901 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,090,527 - 1,100,628 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,537,395 - 1,539,601 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,885,362 - 6,887,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,842,433 - 5,844,639 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,798,934 - 10,801,140 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,798,946 - 10,801,140 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,790,602 - 9,792,808 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,416,121 - 7,418,327 (-)NCBICelera
Cytogenetic Map9q11NCBI
LOC100973655
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21418,217,371 - 18,247,982 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,321,794 - 9,350,556 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v021468,156 - 495,596 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,763,448 - 4,767,394 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,763,674 - 4,765,683 (+)Ensemblpanpan1.1panPan2
FEM1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,971,654 - 54,975,236 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,973,083 - 54,975,104 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,696,306 - 54,699,889 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,626,045 - 55,629,628 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,627,467 - 55,629,489 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,687,398 - 54,690,980 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,167,987 - 55,171,571 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,365,967 - 55,369,558 (-)NCBIUU_Cfam_GSD_1.0
Fem1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,023,045 - 215,026,253 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,808,679 - 2,810,616 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,808,561 - 2,811,738 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEM1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,042,989 - 74,044,983 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,041,391 - 74,045,123 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103233730
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,503,012 - 4,506,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl64,503,146 - 4,505,155 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023668252660 - 4,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fem1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248284,990,299 - 4,992,287 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248284,989,025 - 4,992,730 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000010150   ⟹   ENSCLAP00000010020
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554954,215,284 - 4,217,230 (-)Ensembl
RefSeq Acc Id: XM_005405778   ⟹   XP_005405835
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554954,214,250 - 4,217,313 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005405835 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010020.1
RefSeq Acc Id: XP_005405835   ⟸   XM_005405778
- UniProtKB: A0A8C2YMQ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000010020   ⟸   ENSCLAT00000010150


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006945 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010150.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  CRL2_E3_Ligase_Fem-1 UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene Fem1a ENTREZGENE
PANTHER ANKYRIN REPEAT CONTAINING UniProtKB/TrEMBL
  ANKYRIN REPEAT DOMAIN 16 UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2YMQ8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Fem1a  fem-1 homolog A    fem-1 homolog a (C. elegans)  Symbol and/or name change 5135510 APPROVED