Vps53 (VPS53 subunit of GARP complex) - Rat Genome Database

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Gene: Vps53 (VPS53 subunit of GARP complex) Chinchilla lanigera
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Symbol: Vps53
Name: VPS53 subunit of GARP complex
RGD ID: 8809016
Description: INVOLVED IN endocytic recycling (ortholog); lysosomal transport (ortholog); protein targeting to lysosome (ortholog); ASSOCIATED WITH genetic disease (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (ortholog); EARP complex (ortholog); GARP complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vacuolar protein sorting 53 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 53 homolog; VPS53, GARP complex subunit
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,130,888 - 2,264,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,130,669 - 2,265,065 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Vps53
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,130,888 - 2,264,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,130,669 - 2,265,065 (-)NCBIChiLan1.0ChiLan1.0
VPS53
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3817508,668 - 714,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl17508,503 - 721,717 (-)EnsemblGRCh38hg38GRCh38
GRCh3717411,908 - 618,079 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617382,698 - 564,758 (-)NCBINCBI36Build 36hg18NCBI36
Celera17423,924 - 629,862 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef17325,008 - 528,642 (-)NCBIHuRef
CHM1_117418,907 - 623,396 (-)NCBICHM1_1
T2T-CHM13v2.017391,960 - 599,311 (-)NCBIT2T-CHM13v2.0
Vps53
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,937,052 - 76,070,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,937,052 - 76,070,473 (-)EnsemblGRCm39 Ensembl
GRCm381176,046,226 - 76,179,638 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,046,226 - 76,179,647 (-)EnsemblGRCm38mm10GRCm38
MGSCv371175,859,728 - 75,993,132 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,862,421 - 75,995,825 (-)NCBIMGSCv36mm8
Celera1183,555,285 - 83,692,488 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
Vps53
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81061,418,076 - 61,536,912 (-)NCBIGRCr8
mRatBN7.21060,919,820 - 61,038,674 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,919,820 - 61,038,676 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,561,939 - 65,680,825 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,067,390 - 65,186,273 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,537,918 - 60,656,979 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01064,218,596 - 64,341,064 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1064,222,276 - 64,341,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,672,733 - 63,793,858 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,410,886 - 63,535,682 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11063,424,683 - 63,543,200 (-)NCBI
Celera1059,935,404 - 60,054,107 (-)NCBICelera
Cytogenetic Map10q24NCBI
VPS53
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,042,929 - 8,261,718 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1179,602,776 - 9,812,194 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017400,048 - 576,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117416,136 - 604,705 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17414,782 - 604,705 (-)Ensemblpanpan1.1panPan2
VPS53
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,074,066 - 45,239,569 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,074,100 - 45,214,066 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha944,224,566 - 44,391,993 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0945,892,548 - 46,060,240 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl945,892,566 - 46,035,516 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1944,670,971 - 44,838,890 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0944,964,695 - 45,132,085 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,043,233 - 45,211,135 (+)NCBIUU_Cfam_GSD_1.0
Vps53
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,189,381 - 44,329,957 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,067,327 - 7,205,768 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,067,332 - 7,207,852 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS53
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,143,098 - 47,291,161 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,141,749 - 47,291,169 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,308,850 - 49,456,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VPS53
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116302,771 - 464,572 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16303,414 - 464,574 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605921,622,848 - 21,752,483 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vps53
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247863,614,811 - 3,778,069 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247863,614,775 - 3,779,644 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000015614   ⟹   ENSCLAP00000015452
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554812,130,888 - 2,264,924 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000015615   ⟹   ENSCLAP00000015453
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554812,130,888 - 2,264,924 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000015616   ⟹   ENSCLAP00000015454
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554812,130,888 - 2,264,924 (-)Ensembl
RefSeq Acc Id: XM_013503465   ⟹   XP_013358919
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554812,130,669 - 2,265,065 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013358919 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015452
  ENSCLAP00000015452.1
  ENSCLAP00000015453.1
  ENSCLAP00000015454.1
RefSeq Acc Id: XP_013358919   ⟸   XM_013503465
- UniProtKB: A0A8C2VJ34 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000015452   ⟸   ENSCLAT00000015614
Ensembl Acc Id: ENSCLAP00000015454   ⟸   ENSCLAT00000015616
Ensembl Acc Id: ENSCLAP00000015453   ⟸   ENSCLAT00000015615
Protein Domains
Vps53 C-terminal   Vps53 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015614 ENTREZGENE
  ENSCLAT00000015614.1 UniProtKB/TrEMBL
  ENSCLAT00000015615.1 UniProtKB/TrEMBL
  ENSCLAT00000015616.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.110 UniProtKB/TrEMBL
  Methyl-accepting chemotaxis protein UniProtKB/TrEMBL
InterPro Vps53 UniProtKB/TrEMBL
  Vps53_C UniProtKB/TrEMBL
  Vps53_C_sf UniProtKB/TrEMBL
  Vps53_N UniProtKB/TrEMBL
NCBI Gene Vps53 ENTREZGENE
PANTHER PTHR12820 UniProtKB/TrEMBL
  VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG UniProtKB/TrEMBL
Pfam VPS53_C UniProtKB/TrEMBL
  Vps53_N UniProtKB/TrEMBL
UniProt A0A8C2VGY2_CHILA UniProtKB/TrEMBL
  A0A8C2VJ34 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VME0_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Vps53  VPS53 subunit of GARP complex    VPS53, GARP complex subunit  Symbol and/or name change 5135510 APPROVED
2016-08-03 Vps53  VPS53, GARP complex subunit    vacuolar protein sorting 53 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED