Phox2a (paired like homeobox 2A) - Rat Genome Database

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Gene: Phox2a (paired like homeobox 2A) Chinchilla lanigera
Analyze
Symbol: Phox2a
Name: paired like homeobox 2A
RGD ID: 8803046
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN locus ceruleus development (ortholog); midbrain development (ortholog); noradrenergic neuron differentiation (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); cerebral folate receptor alpha deficiency (ortholog); congenital fibrosis of the extraocular muscles 2 (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: paired mesoderm homeobox protein 2A; paired-like homeobox 2a
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541419,141,589 - 19,145,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541419,141,589 - 19,145,486 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Phox2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541419,141,589 - 19,145,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541419,141,589 - 19,145,486 (+)NCBIChiLan1.0ChiLan1.0
PHOX2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,239,077 - 72,244,176 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1172,239,077 - 72,245,664 (-)EnsemblGRCh38hg38GRCh38
GRCh371171,950,121 - 71,955,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,627,769 - 71,632,852 (-)NCBINCBI36Build 36hg18NCBI36
Build 341171,627,769 - 71,632,852NCBI
Celera1169,251,525 - 69,256,623 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1168,243,281 - 68,248,023 (-)NCBIHuRef
CHM1_11171,833,572 - 71,838,671 (-)NCBICHM1_1
T2T-CHM13v2.01172,165,694 - 72,170,794 (-)NCBIT2T-CHM13v2.0
Phox2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,467,520 - 101,471,933 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,467,520 - 101,471,933 (+)EnsemblGRCm39 Ensembl
GRCm387101,818,313 - 101,822,726 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,818,313 - 101,822,726 (+)EnsemblGRCm38mm10GRCm38
MGSCv377108,966,827 - 108,971,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367101,692,311 - 101,696,547 (+)NCBIMGSCv36mm8
Celera7102,190,059 - 102,194,443 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.66NCBI
Phox2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81165,590,757 - 165,595,122 (+)NCBIGRCr8
mRatBN7.21156,178,754 - 156,183,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,178,754 - 156,183,118 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,169,073 - 164,173,439 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,349,162 - 171,353,527 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,226,678 - 164,231,045 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,893,734 - 166,898,252 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,893,734 - 166,898,252 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,083,448 - 173,087,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,273,524 - 159,312,136 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11159,352,540 - 159,356,748 (+)NCBI
Celera1154,257,374 - 154,261,739 (+)NCBICelera
RH 3.4 Map11272.9RGD
Cytogenetic Map1q32NCBI
PHOX2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,186,167 - 73,191,264 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,229,581 - 74,234,688 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,317,747 - 67,322,850 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,542,242 - 70,546,305 (-)NCBIpanpan1.1PanPan1.1panPan2
PHOX2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,895,628 - 25,900,338 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2125,892,321 - 25,900,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,665,337 - 25,670,038 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,104,275 - 26,108,976 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,104,334 - 26,108,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,895,746 - 25,900,444 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,111,941 - 26,116,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,013,496 - 26,018,198 (+)NCBIUU_Cfam_GSD_1.0
Phox2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,940,335 - 59,944,949 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364981,540,484 - 1,544,360 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364981,539,939 - 1,544,469 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHOX2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,807,623 - 6,812,578 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,808,144 - 6,831,636 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,570,140 - 7,586,515 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHOX2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,459,031 - 63,464,674 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,459,719 - 63,463,894 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604362,420,425 - 62,425,613 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phox2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248174,775,258 - 4,779,303 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248174,775,176 - 4,779,694 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000023628   ⟹   ENSCLAP00000023407
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541419,141,589 - 19,145,486 (+)Ensembl
RefSeq Acc Id: XM_005380455   ⟹   XP_005380512
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541419,141,589 - 19,145,486 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005380512 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000023407
  ENSCLAP00000023407.1
RefSeq Acc Id: XP_005380512   ⟸   XM_005380455
- UniProtKB: A0A8C2YU40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000023407   ⟸   ENSCLAT00000023628
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016051 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023628 ENTREZGENE
  ENSCLAT00000023628.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Paired_Homeobox_TFs UniProtKB/TrEMBL
NCBI Gene Phox2a ENTREZGENE
PANTHER HOMEOBOX PROTEIN ARISTALESS UniProtKB/TrEMBL
  PAIRED MESODERM HOMEOBOX PROTEIN 2A UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C2YU40 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-24 Phox2a  paired like homeobox 2A    paired like homeobox 2a  Symbol and/or name change 5135510 APPROVED
2016-08-03 Phox2a  paired like homeobox 2a    paired-like homeobox 2a  Symbol and/or name change 5135510 APPROVED