PHOX2A (paired like homeobox 2A) - Rat Genome Database

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Gene: PHOX2A (paired like homeobox 2A) Pan paniscus
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Symbol: PHOX2A
Name: paired like homeobox 2A
RGD ID: 11688292
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN locus ceruleus development (ortholog); midbrain development (ortholog); noradrenergic neuron differentiation (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); cerebral folate receptor alpha deficiency (ortholog); congenital fibrosis of the extraocular muscles 2 (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: paired mesoderm homeobox protein 2A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,186,167 - 73,191,264 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,229,581 - 74,234,688 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,317,747 - 67,322,850 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,542,242 - 70,546,305 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PHOX2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,186,167 - 73,191,264 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,229,581 - 74,234,688 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,317,747 - 67,322,850 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,542,242 - 70,546,305 (-)NCBIpanpan1.1PanPan1.1panPan2
PHOX2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,239,077 - 72,244,176 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1172,239,077 - 72,245,664 (-)EnsemblGRCh38hg38GRCh38
GRCh371171,950,121 - 71,955,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,627,769 - 71,632,852 (-)NCBINCBI36Build 36hg18NCBI36
Build 341171,627,769 - 71,632,852NCBI
Celera1169,251,525 - 69,256,623 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1168,243,281 - 68,248,023 (-)NCBIHuRef
CHM1_11171,833,572 - 71,838,671 (-)NCBICHM1_1
T2T-CHM13v2.01172,165,694 - 72,170,794 (-)NCBIT2T-CHM13v2.0
Phox2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,467,520 - 101,471,933 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,467,520 - 101,471,933 (+)EnsemblGRCm39 Ensembl
GRCm387101,818,313 - 101,822,726 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,818,313 - 101,822,726 (+)EnsemblGRCm38mm10GRCm38
MGSCv377108,966,827 - 108,971,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367101,692,311 - 101,696,547 (+)NCBIMGSCv36mm8
Celera7102,190,059 - 102,194,443 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.66NCBI
Phox2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81165,590,757 - 165,595,122 (+)NCBIGRCr8
mRatBN7.21156,178,754 - 156,183,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,178,754 - 156,183,118 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,169,073 - 164,173,439 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,349,162 - 171,353,527 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,226,678 - 164,231,045 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,893,734 - 166,898,252 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,893,734 - 166,898,252 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,083,448 - 173,087,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,273,524 - 159,312,136 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11159,352,540 - 159,356,748 (+)NCBI
Celera1154,257,374 - 154,261,739 (+)NCBICelera
RH 3.4 Map11272.9RGD
Cytogenetic Map1q32NCBI
Phox2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541419,141,589 - 19,145,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541419,141,589 - 19,145,486 (+)NCBIChiLan1.0ChiLan1.0
PHOX2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,895,628 - 25,900,338 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2125,892,321 - 25,900,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,665,337 - 25,670,038 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,104,275 - 26,108,976 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,104,334 - 26,108,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,895,746 - 25,900,444 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,111,941 - 26,116,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,013,496 - 26,018,198 (+)NCBIUU_Cfam_GSD_1.0
Phox2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,940,335 - 59,944,949 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364981,540,484 - 1,544,360 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364981,539,939 - 1,544,469 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHOX2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,807,623 - 6,812,578 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,808,144 - 6,831,636 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,570,140 - 7,586,515 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHOX2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,459,031 - 63,464,674 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,459,719 - 63,463,894 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604362,420,425 - 62,425,613 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phox2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248174,775,258 - 4,779,303 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248174,775,176 - 4,779,694 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_063608215   ⟹   XP_063464285
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,186,167 - 73,191,264 (-)NCBI
RefSeq Acc Id: XM_063608216   ⟹   XP_063464286
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,186,498 - 73,191,264 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063464285 (Get FASTA)   NCBI Sequence Viewer  
  XP_063464286 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_063464285   ⟸   XM_063608215
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063464286   ⟸   XM_063608216
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
NCBI Gene PHOX2A ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-24 PHOX2A  paired like homeobox 2A    paired like homeobox 2a  Symbol and/or name change 5135510 APPROVED