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Gene: Prag1 (PEAK1 related, kinase-activating pseudokinase 1) Chinchilla lanigera

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Symbol:

Prag1

Name:

PEAK1 related, kinase-activating pseudokinase 1

RGD ID:

8786469

Description:

ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell migration (ortholog); negative regulation of neuron projection development (ortholog); positive regulation of Rho protein signal transduction (ortholog); FOUND IN cytoplasm (ortholog); focal adhesion (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC102016357; PEAK1 related kinase activating pseudokinase 1; tyrosine-protein kinase SgK223

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	4,394,718 - 4,446,696 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	4,397,246 - 4,446,696 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (ISO)

negative regulation of neuron projection development (ISO)

positive regulation of Rho protein signal transduction (ISO)

regulation of cell motility (ISO)

regulation of cell shape (ISO)

regulation of Notch signaling pathway (ISO)

Cellular Component

cytoplasm (ISO)

focal adhesion (ISO)

nucleus (ISO)

Molecular Function

ATP binding (ISO)

identical protein binding (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Prag1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	4,394,718 - 4,446,696 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	4,397,246 - 4,446,696 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRAG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	8,317,736 - 8,386,439 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	8,317,736 - 8,386,439 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	8,175,258 - 8,243,949 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	8,212,668 - 8,276,667 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	7,303,570 - 7,367,558 (-)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	7,099,920 - 7,163,897 (-)	NCBI		HuRef
CHM1_1	8	8,240,753 - 8,304,766 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	11,357,159 - 11,425,856 (+)	NCBI		T2T-CHM13v2.0

Prag1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	36,562,015 - 36,614,939 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	36,561,982 - 36,614,941 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	36,094,827 - 36,147,787 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	36,094,828 - 36,147,787 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	37,157,882 - 37,210,841 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	37,563,378 - 37,616,061 (+)	NCBI		MGSCv36	mm8
Celera	8	38,730,743 - 38,787,704 (+)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	22.78	NCBI

Prag1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	62,791,249 - 62,844,532 (-)	NCBI		GRCr8
mRatBN7.2	16	56,087,885 - 56,141,153 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	56,087,885 - 56,141,153 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	61,401,186 - 61,454,452 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	64,815,158 - 64,868,428 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	60,035,139 - 60,088,409 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	59,666,794 - 59,730,681 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	59,666,775 - 59,721,227 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	59,345,052 - 59,397,741 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	59,780,251 - 59,833,359 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	59,780,708 - 59,828,812 (-)	NCBI
Celera	16	54,144,709 - 54,196,468 (-)	NCBI		Celera
Cytogenetic Map	16	q12.2	NCBI

PRAG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	24,771,690 - 24,842,864 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	798,821 - 870,444 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	10,824,887 - 10,896,058 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

PRAG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	36,058,527 - 36,103,933 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	36,053,967 - 36,103,764 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	36,509,721 - 36,568,184 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	38,083,633 - 38,142,148 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	38,096,813 - 38,142,148 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	36,183,300 - 36,241,596 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	36,745,966 - 36,804,272 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	36,865,728 - 36,924,087 (+)	NCBI		UU_Cfam_GSD_1.0

Prag1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	43,045,601 - 43,101,519 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936573	2,046,036 - 2,094,040 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936573	2,040,965 - 2,095,377 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRAG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	17	745,039 - 793,409 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PRAG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	10,641,633 - 10,704,068 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	10,629,078 - 10,703,646 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	31,689,333 - 31,756,969 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prag1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624839	4,361,051 - 4,413,061 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624839	4,363,337 - 4,417,585 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005398353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01049605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01181338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01076008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000001042 ⟹ ENSCLAP00000001004

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955463	4,394,718 - 4,446,696 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000001043 ⟹ ENSCLAP00000001005

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955463	4,397,611 - 4,442,239 (-)	Ensembl

RefSeq Acc Id:

XM_005398353 ⟹ XP_005398410

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955463	4,397,246 - 4,446,696 (-)	NCBI

Sequence:

show sequence

GGCGCCGCCGGGAGGGCGCTGGAGGTGCTCCGAGGGGCCGGGCGCGCCGGCCTGGGGGCGCGGG
GCGGCGGCGCGGACTGCAGAGGTGCGGGCGCCGGGGCGGGCGGCGTAACCGGAGGCGGAGGGGG
CGGAGCCGAGCTCGCAGCTGCCACCCGGCCGCCGGGCCCAGGCAGAAGACACCGCCCGCGGCCG
GGCACGCACCGCGCGCAGTCACTCCGCGAACAATGCTCCGAGGCGCCCGGGCGGGCGGCGGACC
GCTGGGCCACCGACGGCGAGGCCCGGGCAGCGCAGCCCCGAGGAGGCCTGTCTGGGACCCACCC
CTGCCTCCCACAAGACCATACCCGAGAGCCGGGCTCAAGATGAACCAGCACACTCTTAGCTCAC
GATGCTCCAGGCCACCCAACTGAACTGTGAGAGCCCAAAAATGTCTGCGTGCAGTGACTTTGTG
GAGCACATCTGGAAGCCCGGGTCCTGCAAGAACTGCTTCTGTCTGCGGAGTGACCACCAGCTGG
CAGCTGGCCGTCCCCAGCCCAGAACAAGCAGCCTGCCCCCTCCACCTCGCCTGCCCCCCAAGAG
TGTGGAAGATGAAAGTGTGAATGGCTCACCCTATTGCAAGCCCACAATCGCTGTGAAACCCACC
ATGATGAGCTCCGAGGCCTCGGATGTGTGGACAGAGGCCAGCCTGAGTACTGAAGTCCCACAGG
TTATCTGGAGACGAGCCCATGGCAAACTACCCCTCCCAAAGCAGGAAGACGTGCCCATAGTCTA
CCTGGGCAGCTTCCGTGGCGTCCAGAAGCCTGCTAGCCCCTCTGCCTGTAAGGATGGCAGCTCT
CACTGTCCGCCTGCCTATGCCATGGTTGGTCTGCACAGCCTGCAGGCGCAGGGGGAAAGGAACA
TGGCCTTCCACCCCGTGGGTTTCCCAGATGAGAAGGCTGGGCAGGAAGGGAAGCCCACATTTCC
CTGCCAAGAGCTGCCCTCTGCGCAGGAGAGCTTCCGCCAGAAACTGGCTGCCTTTGCTGGGATG
ACATCTGGCTGTCACAAAGGCCCCAGGCCCTGCCCTTCTCCACAGCCCTTGCAGGAGTCCCTGC
CCTCAGAAGACGAAAGTGATCAAAGGTGTTCCCCGTCTGGAGACAGCGAAGGTGGTGAATACTG
CTCCATCCTGGACTGCTGCCCCAGGAGCTCGGCTGCCAAGGATACCGCACACTCGGAGAGCTCC
CAGGGCAGATGTGGAAGGGGCAGCTCCTCCCCGATGTGCTGGGAGCAGGGATCATGTGCTCGGC
CCCCAGAGGAGGAGAAGCAGAGTCCGAGCTTCCCCAGGGAGTGCTGTGGCCAGGGCCCCTCAGC
ACACCCCCCCCACCTGGGGCCCAAGAAGCCATCCCTCAACTCTGAGGCTGCCAGTTCTTCAGAC
GGCCTGTCTTGTGGCAGTGGCAGTAGTGGGGCCAGCAGCCCCTTCACCCCCCATCTTGAGAGTG
ATTACTGCTCCCTCATGAAGGAAGCTGTGCCGCCAGGGAAGCAGCAGGACTCTGCCTGCCGTGT
GATCACCTCTAGCAGGTGCACGGAGTCCCAGCCCCCGGCACACCCCAGGGAGGCTGCACAGCCG
GAACCCATCTATGCCGAGAGCACCAAGAGAAAGAAGGCAGTTCCAGTGCCTTCCAGGCCACAGG
CCAAGGCAGAGCAGGCAGCTGCTGCTCAGGGCCAGGTACGGACAGGTGATGCCAGGGCTCAGAA
AACCCCCTGTGTCTGGAGCCGGGACAGAGAAGGCTCGGATATGGCTCCCCAGGTGTCGGCCACC
ATCACAGTCATGGCCACCCACCCAGAAGAGGACCACCGGACCATCTACCTGAGCAGCCCAGACT
CTGCAGTGGGTGTGCAGTGGCCGCGGGGGCCTGTGGGCCAGGACTTGGAGGCCGGCAAGGAGGA
GCCTGTGGCTGGACAGGGGCCCAGCTCCAAGGAAAGCCATCCTCCTGACAGGTCTGAAAACACG
CCCCAGGGGAGGCCCGCCATCCCCCCCAAGCTGTCCAAGAGCAGCCCTAGTGGGTCCCCGGCAT
CGCCATCTGCTTCCTCACTGGCTGACCCCAACGAGGGGAGCTCAGGCAGCAGCAAACCCCAGTC
TTCATCCAGAGATTTGGCTGACCCCACTTCTTCCTGCCGGACCAGTGACCTTGCCAGGGGCCCT
CCTCCTGCTGCCTCCACCTCAGCCTCAGACCAGAGGTGGCCCAGGTACCAGACCAGTGCCTGGA
GTCGCCAGTGCCGCATCGAGGAGGAGGAGGAAGTGGAGCAGGAACTGTTGAGTCAGAGCTGGGG
AAGAGAGATGGATAATGGCACTGTGGACCATTCAAACTCTTCTACCTGGCACCGTCTCCACCCC
ACCGACGGCTCCTCTGGGCAGAACAGCAAAGTCGGGACTGGGATGAGCAAGTCTGCCTCCTTTG
CCTTTGAGTTCCCCAAGGACAGAAGCAGGATGGAGGCTTTCTCACCTCCTCCCCCACCTCCAAA
GTCCAGGCACCTTTTAAAAATGAACAAGAGCAGCTCTGATTTGGAAAAAGTGAGCCAGGGCTCT
GCAGAGAGCCTCAGCCCATCCTTCCGGGGCGTCCACATCAGCTTCGCCACCAGCTCCACAGACA
GCCTGGCTTCAGACTCCAGGACCTGCAGTGATGGAGGGCCATCTTCTGAGCCAGCACACTCGCC
CACCATCAGCGGGAAGAAGCTCTTTGCTCCGGTCCCGTTCCCATTGGGCTCCACTGAGAATGTG
TCCCCCAGTGGCTCTGTGCAGCCCCCTCCCCTTCCCCAGAAGAAGATAGTGAGCCGAGCGGCCT
CCTCTCCCGATGGTGTCTTCTGGACCCAAGGCTCCCCTAAGCCACGAACAGCAAGCCCAAAGCT
GAACCTAAGCCACTCGGAAACCAACGTATCTGCCCAGGATGAGTCTCACTTTGGTTATTCCCTG
AGCCCAGGGAGCCGCCACCCTATCTTCTCCTCTTCTGAGCCTCTGGAGAAAGCTTTCAAAGGCA
GCAGTCCCTGGGTCCCAGCTCCGGGGCTGGCGGGCAGCAAAAGCAGCTGTGGGAGCCCCAGCCT
GCAGTGCAGAGCAGCTCCCTCCACCTCATCCTCACAGCTGAGTGTGTCCAGCCAGGCCTCCTCC
AGTAGCACTCAGCTGCAGCTGCACAGCCTCCTGAGCAGCATCAGCAGCAAGGAAGGCACCTACG
CCAAGCTAGGCGGGCTCTACACACAGTCCCTGGCCCGCCTTGTGGCCAAGTGTGAGGACCTCTT
CATGGGTGGCCAGAAGAAGGAGCTCCACTTCAATGAGAATAACTGGTCGCTCTTCAAACTGACT
TGTAACAAGCCCTGCTGTGACTCGGGAGATGCCATTTATTACTGTGCCACCTGCTCCGAAGACC
CAGGCAGCACCTATGCTGTGAAAATCTGCAAAACCCCTGAGCCCAAAACAACGTCATACAGTAG
CCCCTCTGTGCCGGTTCACTTCAACATCCAGCAGGACTGTGGCCACTTTGTTGCCTCTGTGCCC
TCCAGCATGCTTACCTCCTCTGACACGACCAAGGACCATCTGCCTGCTGCAGTCTCACAGCCCC
CTGCCCAGGAACAGGACTGCGTGGTGGTCATCACCCGAGAGGTGCCCTACCAGACGGCCTCGGA
CTTCGTGCGAGACTCAGCCACCAGCCATCAGGCTGAGCCTGAGGTGTACGAGCGGCGTGTGTGC
TTCCTCCTTCTGCAGCTCTGCAATGGGCTGGAGCACCTGAAAGAGCACGGTATCATCCACAGGG
ACCTGTGCCTGGAGAACCTGCTGCTGGTGCACTGTAGCCCCCAGGCCTGCCCAGGGCCCTCCTC
TGCCGCCTCCACGCTGTCCACTGCCACCTCTGCTTGCTCCCCTGCTGTCCCCCCTTCCACCGTT
GCTCCCAACCCCCTTGCTGCCTCCACTTGTCAGGTAGTGCCCAGTGAGAAGCACCTGCCCCGGC
TCATCATCAGCAATTTCCTGAAGGCCAAGCAGAAGCCAGGAGGCACCGCCAACCTGCAAAAGAA
GAAGAGCCAGGCCCGGCTGGCCCCTGAGATTGTGTCTGCCTCGCAGTACCGCAAATTTGATGAG
TTCCAGACCGGCATCCTCATTTACGAGCTGCTCCACCAGCCCAACCCATTTGAGGTGCGGGCCC
AGCTGCGGGAGCAGGACTACCGGCGGGAAGACCTGCCCCCACTGCCCGCCCTGTCCCTCTACTC
GCCCGGCCTGCAGCAGCTCGCTCACCTGCTGCTAGAGGCTGACCCCATCAAGCGCATCCGCATA
GGGGAGGCCAAGCATGTGCTGCAGTGCTTGCTGTGGGGCCCCCGGCGCGAGCTGGTGGAGCAGC
CAGGCTCCTCGGAGGAGGTGCTGTGCAGCACGCTACACAACTGGATTGACATGAAGCGGGCCCT
GATGATGATGAAGTTTGCAGAGAAGGCGGTGGACCGCAGGCGGGGTGTGGAGTTGGAGGACTGG
CTTTGCTGCCAGTACTTGGCAGCTGCAGAACCCGCAGCCCTCTTGCAGTCACTGAAGCTCCTGC
AGCTTCTGTGAGCAAAGCCCTTCCCTGCACTGTGCTGCCCGCTTGCACCCAGCCCAGGCCTTTG
CCTTGCTAGGGAAATGGTACAAATGACTGTCACTCTTGGATGTAATATATATAAAATATATATA
ATATATAAATATGAAAGGCTGAGGATGTCATTGCCTGCTCTGGTCACCTCTCCTCACCAGCTCC
TCTCCCCACAGTTTTCTCTTGTAATTATGTACATTTCTAGCTCTGTGCAAGCTCTTAAGTACTG
TTCTGCCAACAGAATGGAGCCTGGCATCCAGCCTCAGCACCCCGCTGTGGAATCTATTTGCCCT
CTTGCCAAATTGTTATTTAAAAAACAACAATAAAAAAAAAACTATCAGTTAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005398410	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000001004
	ENSCLAP00000001004.1
	ENSCLAP00000001005.1

RefSeq Acc Id:

XP_005398410 ⟸ XM_005398353

- UniProtKB:

A0A8C2UJL4 (UniProtKB/TrEMBL), A0A8C2YIF2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLQATQLNCESPKMSACSDFVEHIWKPGSCKNCFCLRSDHQLAAGRPQPRTSSLPPPPRLPPKS
VEDESVNGSPYCKPTIAVKPTMMSSEASDVWTEASLSTEVPQVIWRRAHGKLPLPKQEDVPIVY
LGSFRGVQKPASPSACKDGSSHCPPAYAMVGLHSLQAQGERNMAFHPVGFPDEKAGQEGKPTFP
CQELPSAQESFRQKLAAFAGMTSGCHKGPRPCPSPQPLQESLPSEDESDQRCSPSGDSEGGEYC
SILDCCPRSSAAKDTAHSESSQGRCGRGSSSPMCWEQGSCARPPEEEKQSPSFPRECCGQGPSA
HPPHLGPKKPSLNSEAASSSDGLSCGSGSSGASSPFTPHLESDYCSLMKEAVPPGKQQDSACRV
ITSSRCTESQPPAHPREAAQPEPIYAESTKRKKAVPVPSRPQAKAEQAAAAQGQVRTGDARAQK
TPCVWSRDREGSDMAPQVSATITVMATHPEEDHRTIYLSSPDSAVGVQWPRGPVGQDLEAGKEE
PVAGQGPSSKESHPPDRSENTPQGRPAIPPKLSKSSPSGSPASPSASSLADPNEGSSGSSKPQS
SSRDLADPTSSCRTSDLARGPPPAASTSASDQRWPRYQTSAWSRQCRIEEEEEVEQELLSQSWG
REMDNGTVDHSNSSTWHRLHPTDGSSGQNSKVGTGMSKSASFAFEFPKDRSRMEAFSPPPPPPK
SRHLLKMNKSSSDLEKVSQGSAESLSPSFRGVHISFATSSTDSLASDSRTCSDGGPSSEPAHSP
TISGKKLFAPVPFPLGSTENVSPSGSVQPPPLPQKKIVSRAASSPDGVFWTQGSPKPRTASPKL
NLSHSETNVSAQDESHFGYSLSPGSRHPIFSSSEPLEKAFKGSSPWVPAPGLAGSKSSCGSPSL
QCRAAPSTSSSQLSVSSQASSSSTQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVAKCEDLF
MGGQKKELHFNENNWSLFKLTCNKPCCDSGDAIYYCATCSEDPGSTYAVKICKTPEPKTTSYSS
PSVPVHFNIQQDCGHFVASVPSSMLTSSDTTKDHLPAAVSQPPAQEQDCVVVITREVPYQTASD
FVRDSATSHQAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQACPGPSS
AASTLSTATSACSPAVPPSTVAPNPLAASTCQVVPSEKHLPRLIISNFLKAKQKPGGTANLQKK
KSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLREQDYRREDLPPLPALSLYS
PGLQQLAHLLLEADPIKRIRIGEAKHVLQCLLWGPRRELVEQPGSSEEVLCSTLHNWIDMKRAL
MMMKFAEKAVDRRRGVELEDWLCCQYLAAAEPAALLQSLKLLQLL

hide sequence

Ensembl Acc Id:

ENSCLAP00000001004 ⟸ ENSCLAT00000001042

Ensembl Acc Id:

ENSCLAP00000001005 ⟸ ENSCLAT00000001043

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000000774	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000001042	ENTREZGENE
	ENSCLAT00000001042.1	UniProtKB/TrEMBL
	ENSCLAT00000001043.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	MitoQC_Scaffold_Kinases	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	LOC102016357	ENTREZGENE
PANTHER	INACTIVE TYROSINE-PROTEIN KINASE PRAG1	UniProtKB/TrEMBL
	SERINE/THREONINE PROTEIN KINASE	UniProtKB/TrEMBL
Pfam	PK_Tyr_Ser-Thr	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A8C2UJL4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YIF2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-08-08	Prag1	PEAK1 related, kinase-activating pseudokinase 1		PEAK1 related kinase activating pseudokinase 1	Symbol and/or name change	5135510	APPROVED
2016-10-25	Prag1	PEAK1 related kinase activating pseudokinase 1	LOC102016357	tyrosine-protein kinase SgK223	Symbol and/or name change	5135510	APPROVED
2015-08-25	LOC102016357	tyrosine-protein kinase SgK223		tyrosine-protein kinase SgK223-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

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