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Gene: Tpbg (trophoblast glycoprotein) Chinchilla lanigera

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Symbol:

Tpbg

Name:

trophoblast glycoprotein

RGD ID:

8756901

Description:

INVOLVED IN cell chemotaxis (ortholog); dendrite arborization (ortholog); mesenchymal cell migration (ortholog); ASSOCIATED WITH immunodeficiency 23 (ortholog); Prostatic Neoplasms (ortholog); FOUND IN axon terminus (ortholog); cytoplasm (ortholog); dendrite (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TPBG (trophoblast glycoprotein)	NCBI	Ortholog
Mus musculus (house mouse):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955411	10,203,144 - 10,206,711 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

immunodeficiency 23 (ISO)

Prostatic Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell chemotaxis (ISO)

dendrite arborization (ISO)

mesenchymal cell migration (ISO)

negative regulation of cell population proliferation (ISO)

olfactory learning (ISO)

positive regulation of chemotaxis (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of synapse assembly (ISO)

protein localization to plasma membrane (ISO)

synaptic transmission, GABAergic (ISO)

Cellular Component

axon terminus (ISO)

cytoplasm (ISO)

dendrite (ISO)

endoplasmic reticulum (ISO)

plasma membrane (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tpbg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955411	10,203,144 - 10,206,711 (+)	NCBI	ChiLan1.0	ChiLan1.0

TPBG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	82,362,983 - 82,367,420 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	82,363,206 - 82,367,420 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	83,072,700 - 83,077,137 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	83,130,258 - 83,133,347 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	83,130,257 - 83,133,333	NCBI
Celera	6	83,506,010 - 83,510,221 (+)	NCBI		Celera
Cytogenetic Map	6	q14.1	NCBI
HuRef	6	80,300,641 - 80,304,852 (+)	NCBI		HuRef
CHM1_1	6	83,170,653 - 83,174,864 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	83,582,429 - 83,586,866 (+)	NCBI		T2T-CHM13v2.0

Tpbg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	85,724,433 - 85,729,110 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	85,724,433 - 85,729,093 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	85,842,380 - 85,847,057 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	85,842,380 - 85,847,040 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	85,735,987 - 85,740,662 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	85,639,128 - 85,642,507 (+)	NCBI		MGSCv36	mm8
Celera	9	82,936,659 - 82,941,333 (+)	NCBI		Celera
Cytogenetic Map	9	E3.1	NCBI
cM Map	9	46.4	NCBI

Tpbg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	95,673,993 - 95,677,364 (+)	NCBI		GRCr8
mRatBN7.2	8	86,793,953 - 86,797,324 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	86,793,749 - 86,797,741 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	92,462,281 - 92,465,651 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	90,661,732 - 90,665,103 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	88,505,828 - 88,509,196 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	93,491,761 - 93,495,132 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	93,491,761 - 93,495,130 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	93,006,542 - 93,009,913 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	91,075,960 - 91,079,329 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	91,095,414 - 91,098,784 (+)	NCBI
Celera	8	86,406,590 - 86,409,959 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

TPBG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	102,464,594 - 102,473,670 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	100,349,222 - 100,353,825 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	80,265,172 - 80,273,022 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	83,530,184 - 83,536,290 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	83,530,571 - 83,531,915 (+)	Ensembl	panpan1.1		panPan2

TPBG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	42,872,289 - 42,878,071 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	42,871,239 - 42,875,151 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	42,750,516 - 42,753,814 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	43,640,373 - 43,643,675 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	12	42,958,895 - 42,962,193 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	42,928,419 - 42,931,719 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	43,083,154 - 43,086,460 (+)	NCBI		UU_Cfam_GSD_1.0

Tpbg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	78,192,165 - 78,195,794 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936510	8,275,660 - 8,278,367 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936510	8,274,760 - 8,278,955 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TPBG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	83,847,819 - 83,850,881 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	83,847,809 - 83,851,326 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	94,386,257 - 94,388,336 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TPBG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	7,047,658 - 7,051,390 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	7,049,415 - 7,050,680 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	183,264,600 - 183,268,868 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tpbg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624799	12,226,350 - 12,230,701 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624799	12,226,350 - 12,325,178 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013510911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01011775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01011776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01076595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013510911 ⟹ XP_013366365

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955411	10,203,144 - 10,206,711 (+)	NCBI

Sequence:

show sequence

TTAATTTGGGGAAGAGAAAACCTAATGAATCAAGAATGAGTCCGTTCCCCGCCCCCCTTAAAGT
TGCTCTCTGCTCCCGAGTGGCCCAGCCGCCCGGGACGTGCGGGGGCGGGGCCGGCAGCGGCGCG
CTGACTCCAGCGGGAGCCGAAGTTGACATCCAAGGTGCCACTGCGGTGGGGACACTTTCTAAAG
CGTCCTCACACCCTGCTGGGCGTTTGCCGCTGCCGCTGTACCTTTTCCGCTCACTTCCTTCTGC
TGCTGCTTTGTGTCGCTCTGTCACGCCTGAATCTAGCTCCTCGCCGCCAAAGGTGCCCGAAGCA
GGGAGAATTCCACGAGATCCACCAGCGGTTTCGCTCCAGCCCGAGGTCGCGCGGCGGACCGAGC
GAGAGACGCCGGCAGCGGAGGCGAGGAGGCGCGCCCCGGGCGGCGGCAGAGGCGGCCGAGCGCC
GCGCTACTTTCCGGAGGGAAGGAGGGCGGGGCGGCAGCCCGGGAGGGGGCGCCCGCGGCCAGGG
CTCCCGCGTTCCGGCCGCCGAGCCCCCTCCGCGCCCCCCGGAGCAAAGTTTCTGCGCGAGCTTC
CGGCCGGCCCGCGCCCTCCGGGCCCAGCCCCCGCCCGCGGAGCGGCCGCCGCGGCCGCGATGCC
TGCGCCGTGCGCTCGGGGCCCCGCCGCCGGGGACGGGCGGCTGCGGCTGGCGCGCCTGGCGCTG
GTGCTCCTGGGCTGGGTCTCTTCGTGCCCTCCCGCCGCCTCGGCGGCCCCCGCCAGCGCCGCGG
CGCCCTTCCCGGCCTCGGCGGCGTCCGCCCCGCCGCCCCTGCCGAGCCGCTGCCCCGCGCCGTG
CGAGTGCTCCGAGGCGGCGCGCACCGTCAAGTGCGTGAACCGCAACCTGAGCGCGGTGCCCGCC
GACCTGCCCGCCTACACGCGCACCCTCTTCCTCACCGGCAACCAGCTGGCCGTGCTGCCCGCCG
GCGCCTTCGCCCGCCGCCCGCCCCTGGCCGAGCTGGCCGCGCTCAACCTCAGCGGCAGCCGCCT
GGCGCGGGTGCACGCCGCTGCCTTCGAGGACCTGCCCAGCCTGCGGCAGCTCGACCTCAGCCAC
AACCCGCTCGTCCACCTCAGCCCCTTCGCCTTCTCGGGCCTCAACGCCAGCGCCTCGGCCCCCA
GCCCCCTGTCGGAACTGATCCTGAACCACATCGAGCCCCCCGCCGAGCACCTGGACCCGGAACA
GAAACAGAACCAAAGTGTGGAGAGCATGGTGGCCGCGGCCCTGCGGGCGGGCCGCGCGCTGCAG
GGGCTCCGTCGCCTGGAGCTGGCCAGCAATCACCTTCTCTACCTGCCCAGGGACACGCTGGCCC
AGCTGCCTGGCCTCAGGCACCTGGACCTGCGCAACAATTCCCTGGTGAGCCTGACCTACCTGTC
CTTCCGCAACCTTACACACCTAGAACGCCTCCATCTAGAGGACAACGCGCTCAAGGTCCTTCAC
AACGGCACCCTGGCCGAGTTGCAAGGCCTGGAGCGTGTCAAGGTGTTCCTGGACAACAACCCCT
GGGTCTGCGATTGTCACATGGTGGACATGGTGACCTGGCTCAAGGAGACCGAGATAGTGGAGGG
CAAAGCCGGGCTCACCTGTGCGTTCCCAGAAAAAATGAGGAATCACATTCTTGTGGAACTCAAC
ATCTCCGACCTGGACTGTGACCCTATCCTGCCTCCTTCCCTGCAGACTTCTTACGTCTTCCTGG
GTATTGTTTTAGCCCTGATAGGCGCCATTTTCCTCCTCGTTTTGTATTTGAACCGTAAGGGGAT
AAAAAAGTGGATGCACAACATCAGAGATGCCTGCAGGGATCACATGGAAGGGTATCATTACAGA
TACGAAATCAATGCGGACCCCAGGTTAACAAACCTCAGTTCCAATTCAGATGTCTGAGAAACAT
TAGAGGACAGGAAAAAGGACAGCTCTGCATGAGGTGTAGACTTAAGCTTTACCCATACTAGTTT
GCTCCACTTCCCCCCTCCGCTGCAGACATCACTGACTTTAAAAGCAGTGGAGGGGATTTGCTTC
CTTGTCATGTAAAGTTTCTTGGTGTGTTCTGTTAATGTAAAACAATGAACAACTGTGCAGTGTT
ATGCCTTCCTCTTTTCTCGGAACTCCTCGACTCGCGTGGAGGGACTTTCAAGTTTCAGCATGAA
CAAGGACTCTGCTGTCTGGTCTCTCTTAGTACATTGCGAGGTGTAGCACGTGTACCTGCGCAGA
TAGCATTCAACAAAAGCTGCCTCAACTTTTTTGAGAAAAATACTTTATTCAAAAAATATCAGTT
TTATTCTCATGTACCTAAAATTGTGAAGAAAATAATTGCATCCCATAAACTGCCTGCAGACCTT
AGCAAGCTCTAAAAATAACTCCATAGTACACAGGAGCACCTGCATCCCAGAGCATGCTTGCATT
TTACTGTTCTGCATATTACAAAAAATAACTTGCAACTTCAGATGACATCATTGACAAAGTAAAT
TACTTTTTTGATTGCAGTTTATATGAAACTATTGAAGTTTTTTTTTTTTATAAACTGCACGGAG
ATCCAACAAACTGAATTGTTAAAAAAATCAATAAAGATTCTTAAAAGAA

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Protein Sequences


Protein RefSeqs	XP_013366365	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013366365 ⟸ XM_013510911

- Sequence:

show sequence

MSPFPAPLKVALCSRVAQPPGTCGGGAGSGALTPAGAEVDIQGATAVGTLSKASSHPAGRLPLP
LYLFRSLPSAAALCRSVTPESSSSPPKVPEAGRIPRDPPAVSLQPEVARRTERETPAAEARRRA
PGGGRGGRAPRYFPEGRRAGRQPGRGRPRPGLPRSGRRAPSAPPGAKFLRELPAGPRPPGPAPA
RGAAAAAAMPAPCARGPAAGDGRLRLARLALVLLGWVSSCPPAASAAPASAAAPFPASAASAPP
PLPSRCPAPCECSEAARTVKCVNRNLSAVPADLPAYTRTLFLTGNQLAVLPAGAFARRPPLAEL
AALNLSGSRLARVHAAAFEDLPSLRQLDLSHNPLVHLSPFAFSGLNASASAPSPLSELILNHIE
PPAEHLDPEQKQNQSVESMVAAALRAGRALQGLRRLELASNHLLYLPRDTLAQLPGLRHLDLRN
NSLVSLTYLSFRNLTHLERLHLEDNALKVLHNGTLAELQGLERVKVFLDNNPWVCDCHMVDMVT
WLKETEIVEGKAGLTCAFPEKMRNHILVELNISDLDCDPILPPSLQTSYVFLGIVLALIGAIFL
LVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	LOC102015182	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Tpbg	trophoblast glycoprotein	LOC102015182	uncharacterized LOC102015182	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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