PCAT19 (prostate cancer associated transcript 19) - Rat Genome Database

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Gene: PCAT19 (prostate cancer associated transcript 19) Homo sapiens
Analyze
Symbol: PCAT19
Name: prostate cancer associated transcript 19
RGD ID: 7943681
HGNC Page HGNC:49593
Description: INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; fipronil
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: LINC01190; prostate cancer associated transcript 19 (non-protein coding)
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,454,169 - 41,500,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,449,520 - 41,502,015 (-)EnsemblGRCh38hg38GRCh38
GRCh371941,960,074 - 42,006,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera1938,755,282 - 38,806,407 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,391,679 - 38,438,155 (-)NCBIHuRef
CHM1_11941,959,704 - 42,006,179 (-)NCBICHM1_1
T2T-CHM13v2.01944,275,440 - 44,321,937 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PCAT19Human4,4'-sulfonyldiphenol increases methylationEXP 6480464bisphenol S results in increased methylation of PCAT19 geneCTDPMID:31601247
PCAT19Humanbisphenol A decreases methylationEXP 6480464bisphenol A results in decreased methylation of PCAT19 geneCTDPMID:31601247
PCAT19Humanfipronil multiple interactionsEXP 6480464[fipronil co-treated with DEET] results in decreased expression of PCAT19 mRNACTDPMID:28991164
PCAT19HumanN,N-diethyl-m-toluamide multiple interactionsEXP 6480464[fipronil co-treated with DEET] results in decreased expression of PCAT19 mRNACTDPMID:28991164


#
Reference Title
Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
PMID:12477932   PMID:23065704   PMID:24497837   PMID:30033362   PMID:30868666   PMID:32980991   PMID:35615401   PMID:36017918   PMID:36992525  



.

.
Variants in PCAT19
4 total Variants

1 to 4 of 4 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
NR_040109.1(PCAT19):n.1154-2351C>A single nucleotide variant Lung cancer [RCV000101263] Chr19:41458838 [GRCh38]
Chr19:41964744 [GRCh37]
Chr19:19q13.2
uncertain significance
NR_040109.1(PCAT19):n.469A>G single nucleotide variant Lung cancer [RCV000101264] Chr19:41495020 [GRCh38]
Chr19:42000928 [GRCh37]
Chr19:19q13.2
uncertain significance
GRCh38/hg38 19q13.12-13.2(chr19:37319377-42738688)x3 copy number gain See cases [RCV000050636] Chr19:37319377..42738688 [GRCh38]
Chr19:37810279..43242840 [GRCh37]
Chr19:42502119..47934680 [NCBI36]
Chr19:19q13.12-13.2
pathogenic
1 to 4 of 4 rows

Predicted Target Of
Summary Value
Count of predictions:1186
Count of miRNA genes:693
Interacting mature miRNAs:793
Transcripts:ENST00000588495, ENST00000594315, ENST00000595063, ENST00000595837, ENST00000597702, ENST00000598215, ENST00000599801
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597371737GWAS1467811_Hprostate carcinoma QTL GWAS1467811 (human)2e-12prostate carcinoma194147967941479680Human
597475550GWAS1571624_Hprostate carcinoma QTL GWAS1571624 (human)1e-22prostate carcinoma194148002341480024Human
597371736GWAS1467810_Hprostate carcinoma QTL GWAS1467810 (human)1e-08prostate carcinoma194147967941479680Human
597433942GWAS1530016_Htestosterone measurement QTL GWAS1530016 (human)6e-19testosterone measurementserum testosterone level (CMO:0000568)194148002341480024Human
597430103GWAS1526177_Htestosterone measurement QTL GWAS1526177 (human)5e-17testosterone measurementserum testosterone level (CMO:0000568)194148002341480024Human
597446416GWAS1542490_Htestosterone measurement QTL GWAS1542490 (human)5e-10testosterone measurementserum testosterone level (CMO:0000568)194148002341480024Human
597409430GWAS1505504_Hnon-high density lipoprotein cholesterol measurement QTL GWAS1505504 (human)7e-11non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)194146380041463801Human
597410635GWAS1506709_Hprostate carcinoma QTL GWAS1506709 (human)2e-23prostate carcinoma194147967941479680Human
597442092GWAS1538166_Htestosterone measurement QTL GWAS1538166 (human)1e-12testosterone measurementserum testosterone level (CMO:0000568)194148002341480024Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human

1 to 10 of 16 rows



adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2396 2788 2237 4820 1715 2287 4 617 1479 459 2159 6780 5986 44 3697 836 1703 1561 168


1 to 20 of 20 rows
RefSeq Transcripts NR_040109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_136334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001756399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001756400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002958911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC005795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC011526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC243960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK309432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA987050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 20 of 20 rows

Ensembl Acc Id: ENST00000588495
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,164 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000594315
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,455,020 - 41,500,646 (-)Ensembl
Ensembl Acc Id: ENST00000595063
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,455,665 - 41,479,141 (-)Ensembl
Ensembl Acc Id: ENST00000595837
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,455,317 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000597702
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,455,257 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000598215
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,456,029 - 41,500,645 (-)Ensembl
Ensembl Acc Id: ENST00000599801
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,481 - 41,479,141 (-)Ensembl
Ensembl Acc Id: ENST00000650748
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000650788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000650804
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,679 (-)Ensembl
Ensembl Acc Id: ENST00000650991
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,493,913 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000651016
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,667 (-)Ensembl
Ensembl Acc Id: ENST00000651156
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,649 (-)Ensembl
Ensembl Acc Id: ENST00000651285
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,457,149 (-)Ensembl
Ensembl Acc Id: ENST00000651291
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,457,386 (-)Ensembl
Ensembl Acc Id: ENST00000651464
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,457,155 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000651572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,502,015 (-)Ensembl
Ensembl Acc Id: ENST00000651651
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,629 (-)Ensembl
Ensembl Acc Id: ENST00000651712
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,173 - 41,457,299 (-)Ensembl
Ensembl Acc Id: ENST00000651789
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,173 - 41,479,141 (-)Ensembl
Ensembl Acc Id: ENST00000651806
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000651979
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,477,169 - 41,500,641 (-)Ensembl
Ensembl Acc Id: ENST00000652015
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000652127
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,457,280 (-)Ensembl
Ensembl Acc Id: ENST00000652144
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,649 (-)Ensembl
Ensembl Acc Id: ENST00000652160
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,455,713 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000652279
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,173 - 41,457,400 (-)Ensembl
Ensembl Acc Id: ENST00000652333
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,449,520 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000652406
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,164 - 41,500,657 (-)Ensembl
Ensembl Acc Id: ENST00000652484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,479,776 (-)Ensembl
Ensembl Acc Id: ENST00000652511
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,457,149 (-)Ensembl
Ensembl Acc Id: ENST00000652558
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000656967
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000664904
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000668141
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,457,282 (-)Ensembl
Ensembl Acc Id: ENST00000783813
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,454,169 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000783814
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,479,128 - 41,500,646 (-)Ensembl
Ensembl Acc Id: ENST00000783815
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,479,128 - 41,500,646 (-)Ensembl
Ensembl Acc Id: ENST00000783816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,479,128 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000783817
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,479,128 - 41,500,644 (-)Ensembl
Ensembl Acc Id: ENST00000783818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,479,128 - 41,480,545 (-)Ensembl
Ensembl Acc Id: ENST00000783819
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,500,631 - 41,501,255 (-)Ensembl
Ensembl Acc Id: ENST00000783820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,479,128 - 41,479,748 (-)Ensembl
RefSeq Acc Id: NR_040109
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381941,454,169 - 41,500,649 (-)NCBI
GRCh371941,960,074 - 42,006,554 (-)NCBI
HuRef1938,391,679 - 38,438,155 (-)NCBI
CHM1_11941,959,704 - 42,006,184 (-)NCBI
T2T-CHM13v2.01944,275,440 - 44,321,937 (-)NCBI
Sequence:
RefSeq Acc Id: NR_136334
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381941,454,169 - 41,500,649 (-)NCBI
CHM1_11941,959,704 - 42,006,184 (-)NCBI
T2T-CHM13v2.01944,275,440 - 44,321,937 (-)NCBI
Sequence:
RGD ID:15097235
Promoter ID:EPDNEWNC_H2057
Type:initiation region
Name:PCAT19_2
Description:prostate cancer associated transcript 19 [Source:HGNCSymbol;Acc:HGNC:49593]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381941,479,143 - 41,479,203EPDNEWNC
RGD ID:15097234
Promoter ID:EPDNEWNC_H2058
Type:initiation region
Name:PCAT19_1
Description:prostate cancer associated transcript 19 [Source:HGNCSymbol;Acc:HGNC:49593]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381941,500,644 - 41,500,704EPDNEWNC


1 to 40 of 46 rows
Database
Acc Id
Source(s)
COSMIC PCAT19 COSMIC
Ensembl Genes ENSG00000267107 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000588495 ENTREZGENE
  ENST00000652144 ENTREZGENE
GTEx ENSG00000267107 GTEx
HGNC ID HGNC:49593 ENTREZGENE
Human Proteome Map PCAT19 Human Proteome Map
NCBI Gene PCAT19 ENTREZGENE
OMIM 618192 OMIM
RNAcentral URS00001209F3 RNACentral
  URS0000A76AFD RNACentral
  URS0000A776B1 RNACentral
  URS0000D57959 RNACentral
  URS0000E6342D RNACentral
  URS0000E64D70 RNACentral
  URS0000E67A55 RNACentral
  URS0000E68733 RNACentral
  URS0000E6E269 RNACentral
  URS0000E6F498 RNACentral
  URS0000E6FA62 RNACentral
  URS0000E739E2 RNACentral
  URS0000E74A76 RNACentral
  URS0000E75E22 RNACentral
  URS0000E77970 RNACentral
  URS0000E7AEB8 RNACentral
  URS0000E7C2EE RNACentral
  URS0000E7C377 RNACentral
  URS0000E809D8 RNACentral
  URS0000E82BD3 RNACentral
  URS0000E86656 RNACentral
  URS0000E87B25 RNACentral
  URS0000E88ABC RNACentral
  URS0000E8D7FD RNACentral
  URS0000E8DCE9 RNACentral
  URS0000EEC94D RNACentral
  URS0000EEE773 RNACentral
  URS0000EF1233 RNACentral
  URS0000EF2AD3 RNACentral
  URS0000EF2D68 RNACentral
  URS0000EF2E7D RNACentral
1 to 40 of 46 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-22 PCAT19  prostate cancer associated transcript 19    prostate cancer associated transcript 19 (non-protein coding)  Symbol and/or name change 5135510 APPROVED