Gene: Prph2 (peripherin 2) Mus musculus
Analyze
Symbol:
Prph2
Name:
peripherin 2
Description:
Involved in retina development in camera-type eye. Localizes to the photoreceptor outer segment. Used to study retinitis pigmentosa 7. Human ortholog(s) of this gene implicated in choroidal sclerosis; fundus albipunctatus; and retinal disease (multiple). Is expressed in eye; head; retina; and retina outer nuclear layer. Orthologous to human PRPH2 (peripherin 2); PARTICIPATES IN retinitis pigmentosa pathway; amyotrophic lateral sclerosis pathway; INTERACTS WITH paracetamol; sodium fluoride; 17alpha-ethynylestradiol (ortholog).
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
AOFMD; AVMD; Nmf193; peripherin-2; PRPH; Rd-2; Rd2; Rds; retinal degeneration 2; retinal degeneration slow protein; retinal degeneration, slow (retinitis pigmentosa 7); RP7; Tspan22
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PRPH2 (peripherin 2) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Prph2 (peripherin 2) HGNC
NCBI, HomoloGene, Panther
Chinchilla lanigera (long-tailed chinchilla):
Prph2 (peripherin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PRPH2 (peripherin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PRPH2 (peripherin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Prph2 (peripherin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PRPH2 (peripherin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
ROM1 (retinal outer segment membrane protein 1) HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Prph2 (peripherin 2)
Alliance
DIOPT (Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Homo sapiens (human):
PRPH2 (peripherin 2)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
prph2a (peripherin 2a (retinal degeneration, slow))
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, ZFIN)
Danio rerio (zebrafish):
prph2b (peripherin 2b (retinal degeneration, slow))
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam, ZFIN)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 17 46,910,478 - 46,924,933 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 17 47,047,434 - 47,061,875 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 17 46,373,676 - 46,388,117 (+) NCBI mm8 Celera 17 50,346,402 - 50,360,871 (+) NCBI Celera Cytogenetic Map 17 C NCBI cM Map 17 22.91 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
choroid disease ISO RGD:735709 8554872 ClinVar Annotator: match by term: Choroidal Dystrophy ClinVar choroid disease ISO RGD:735709 8554872 ClinVar Annotator: match by term: Choroidal Dystrophy ClinVar PMID:30718709 choroid disease ISO RGD:735709 8554872 ClinVar Annotator: match by term: Choroidal Dystrophy ClinVar PMID:25741868 Choroidal Dystrophy, Central Areolar 2 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Choroidal dystrophy, central areolar 2 ClinVar PMID:19243827 more ... Choroidal Dystrophy, Central Areolar 2 ISO RGD:735709 8554872 ClinVar Annotator: match by term: MACULAR DYSTROPHY, PROGRESSIVE ClinVar PMID:19243827 more ... Choroidal Dystrophy, Central Areolar 2 ISO RGD:735709 8554872 ClinVar Annotator: match by OMIM:613105 ClinVar PMID:14557183 Choroidal Dystrophy, Central Areolar 2 ISO RGD:735709 8554872 ClinVar Annotator: match by OMIM:613105 ClinVar PMID:7493155 more ... cone dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Cone dystrophy ClinVar PMID:19243827 more ... cone-rod dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Cone rod dystrophy ClinVar PMID:19243827 more ... fundus albipunctatus ISO RGD:735709 8554872 ClinVar Annotator: match by term: Pigmentary retinal dystrophy ClinVar PMID:30718709 fundus albipunctatus ISO RGD:735709 8554872 ClinVar Annotator: match by term: Fundus albipunctatus ClinVar PMID:25741868 fundus albipunctatus ISO RGD:735709 8554872 ClinVar Annotator: match by term: Fundus albipunctatus ClinVar fundus albipunctatus ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis punctata albescens, autosomal dominant ClinVar PMID:8485575 fundus dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinal dystrophy ClinVar PMID:30718709 fundus dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinal dystrophy ClinVar PMID:24608669 , PMID:28041643 fundus dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinal dystrophy ClinVar PMID:28041643 macular degeneration ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy ClinVar PMID:28041643 more ... macular degeneration ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy ClinVar PMID:30718709 macular degeneration ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy ClinVar PMID:19243827 more ... macular degeneration ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy ClinVar PMID:28041643 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar PMID:30718709 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar PMID:28041643 more ... patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar PMID:25741868 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar PMID:15370544 more ... patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: PATTERNED DYSTROPHY OF RETINAL PIGMENT EPITHELIUM ClinVar PMID:7710395 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: PATTERNED DYSTROPHY OF RETINAL PIGMENT EPITHELIUM ClinVar PMID:8251014 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar PMID:23847139 , PMID:9443872 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: PATTERNED DYSTROPHY OF RETINAL PIGMENT EPITHELIUM ClinVar PMID:8485574 patterned macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Patterned dystrophy of retinal pigment epithelium ClinVar PMID:11297544 more ... prostate cancer ISO RGD:735709 8554872 ClinVar Annotator: match by term: Prostate cancer ClinVar PMID:23265383 retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa ClinVar PMID:30718709 retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by term: Cone rod dystrophy ClinVar PMID:19243827 more ... retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis Pigmentosa, Dominant ClinVar PMID:19243827 more ... retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa ClinVar PMID:28041643 retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa ClinVar PMID:28041643 , PMID:8449524 retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by null ClinVar retinitis pigmentosa ISO RGD:735709 8554872 ClinVar Annotator: match by term: Cone-Rod Dystrophy, Dominant ClinVar PMID:25741868 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by OMIM:608133 ClinVar PMID:1684223 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa 7 ClinVar retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by null ClinVar PMID:7880786 , PMID:8019570 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by OMIM:608133 ClinVar PMID:8019570 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by term: LEBER CONGENITAL AMAUROSIS 18 ClinVar PMID:23847139 , PMID:9443872 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by OMIM:608133 ClinVar PMID:7880786 , PMID:8111389 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by OMIM:608133 ClinVar PMID:8020945 retinitis pigmentosa 7 ISO RGD:735709 8554872 ClinVar Annotator: match by term: LEBER CONGENITAL AMAUROSIS 18 ClinVar PMID:11297544 more ... Retinitis Pigmentosa 7 with Bull'S-Eye Maculopathy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa 7, with bull's-eye maculopathy ClinVar PMID:8020945 Stargardt disease ISO RGD:735709 8554872 ClinVar Annotator: match by term: Stargardt's disease ClinVar PMID:7880786 , PMID:8111389 vitelliform macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Vitelliform macular dystrophy ClinVar vitelliform macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Vitelliform macular dystrophy ClinVar PMID:25741868 vitelliform macular dystrophy ISO RGD:735709 8554872 ClinVar Annotator: match by term: Vitelliform macular dystrophy ClinVar PMID:30718709 Vitelliform Macular Dystrophy 2 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Vitelliform macular dystrophy type 2 ClinVar PMID:30718709 Vitelliform Macular Dystrophy 3 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy, vitelliform, adult-onset ClinVar PMID:15370544 more ... Vitelliform Macular Dystrophy 3 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy, vitelliform, adult-onset ClinVar Vitelliform Macular Dystrophy 3 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy, vitelliform, adult-onset ClinVar PMID:12566026 Vitelliform Macular Dystrophy 3 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy, vitelliform, adult-onset ClinVar PMID:9338584 Vitelliform Macular Dystrophy 3 ISO RGD:735709 8554872 ClinVar Annotator: match by term: Macular dystrophy, vitelliform, adult-onset ClinVar PMID:8485576 Vitelliform Macular Dystrophy 3 ISO RGD:735709 8554872 ClinVar Annotator: match by term: MACULAR DYSTROPHY, VITELLIFORM, 3 ClinVar PMID:16885924 more ...
Gene-Chemical Interaction Annotations
