Hoxa2 (homeobox A2) - Rat Genome Database

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Gene: Hoxa2 (homeobox A2) Mus musculus
Analyze
Symbol: Hoxa2
Name: homeobox A2
RGD ID: 731539
MGI Page MGI
Description: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic skeletal system development; muscle structure development; and pharyngeal system development. Acts upstream of or within several processes, including regionalization; regulation of transcription by RNA polymerase II; and rhombomere development. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human HOXA2 (homeobox A2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AI324701; homeo box A2; homeobox protein Hox-1.11; homeobox protein Hox-A2; Hox-1.1; Hox-1.11; HOX1.11; MGC151482; MGC151484
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,139,389 - 52,141,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,139,397 - 52,141,811 (-)EnsemblGRCm39 Ensembl
GRCm38652,162,417 - 52,164,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,162,417 - 52,164,831 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,112,510 - 52,114,830 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,092,094 - 52,094,414 (-)NCBIMGSCv36mm8
Celera652,684,174 - 52,686,494 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
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Original Reference(s)
Hoxa2MouseCongenital Microtia  ISOHOXA2 (Homo sapiens)11553827DNA:missense mutation:cds:c.558C>A(p.Q186K)(human)RGD 
Object Symbol
Species
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Original Reference(s)
Hoxa2MouseAthabaskan brainstem dysgenesis syndrome  ISOHOXA2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868
Hoxa2Mousegenetic disease  ISOHOXA2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868
Hoxa2MouseMicrotia, Hearing Impairment, and Cleft Palate  ISOHOXA2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:18394579 more ...
Hoxa2Mousepleomorphic xanthoastrocytoma  ISOHOXA2 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
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Reference
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Original Reference(s)
Hoxa2MouseMicrotia, Hearing Impairment, and Cleft Palate  ISOHOXA2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24239177
Hoxa2MouseStomach Neoplasms  ISOHOXA2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17786296
Object Symbol
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Original Reference(s)
Hoxa2MouseMicrotia, Hearing Impairment, and Cleft Palate  ISOHOXA2 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Hoxa2Mouse17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of HOXA2 mRNACTDPMID:17942748
Hoxa2Mouse17alpha-ethynylestradiol multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HOXA2 mRNACTDPMID:17942748
Hoxa2Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of HOXA2 mRNACTDPMID:19933214 and PMID:24058054
Hoxa2Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of HOXA2 mRNACTDPMID:21570461
Hoxa2Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of HOXA2 mRNACTDPMID:19897914
Hoxa2Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HOXA2 mRNACTDPMID:17942748
Hoxa2Mouse4,4'-sulfonyldiphenol increases methylationISOHOXA2 (Homo sapiens)6480464bisphenol S results in increased methylation of HOXA2 geneCTDPMID:31601247
Hoxa2Mouseacrylamide decreases expressionISOHoxa2 (Rattus norvegicus)6480464Acrylamide results in decreased expression of HOXA2 mRNACTDPMID:28959563
Hoxa2Mouseaflatoxin B1 decreases methylationISOHOXA2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of HOXA2 geneCTDPMID:27153756
Hoxa2Mousealdehydo-D-glucose increases expressionISOHoxa2 (Rattus norvegicus)6480464Glucose results in increased expression of HOXA2 mRNACTDPMID:21818840
Hoxa2Mousealdehydo-D-glucose multiple interactionsEXP 6480464[lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of HOXA2 mRNACTDPMID:37567420
Hoxa2Mouseall-trans-retinoic acid increases expressionISOHOXA2 (Homo sapiens)6480464Tretinoin results in increased expression of HOXA2 mRNACTDPMID:17185360 and PMID:21934132
Hoxa2Mouseall-trans-retinoic acid multiple interactionsEXP 6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA2 mRNACTDPMID:36189433
Hoxa2MouseAllylamine affects expressionISOHoxa2 (Rattus norvegicus)6480464Allylamine affects the expression of HOXA2 mRNACTDPMID:15910882
Hoxa2Mouseammonium chloride affects expressionISOHoxa2 (Rattus norvegicus)6480464Ammonium Chloride affects the expression of HOXA2 mRNACTDPMID:16483693
Hoxa2Mousearotinoid acid multiple interactionsISOHOXA2 (Homo sapiens)6480464[4-(2-(5 more ...CTDPMID:34480604
Hoxa2Mousearsenous acid decreases expressionISOHOXA2 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of HOXA2 mRNACTDPMID:26705709
Hoxa2Mousebenzo[a]pyrene affects methylationISOHOXA2 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of HOXA2 exonCTDPMID:27901495
Hoxa2Mousebeta-lapachone decreases expressionISOHOXA2 (Homo sapiens)6480464beta-lapachone results in decreased expression of HOXA2 mRNACTDPMID:38218311
Hoxa2Mousebis(2-chloroethyl) sulfide decreases expressionEXP 6480464Mustard Gas results in decreased expression of HOXA2 mRNACTDPMID:15674843

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Biological Process
1 to 20 of 31 rows

  
Object Symbol
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Original Reference(s)
Hoxa2Mouseanterior/posterior pattern specification acts_upstream_of_or_withinIMPMGI:18576262290270 PMID:9367425MGIPMID:9367425
Hoxa2Mousebrain segmentation acts_upstream_of_or_withinIMPMGI:18576262290270 PMID:9367425MGIPMID:9367425
Hoxa2Mousecell fate commitment acts_upstream_of_or_withinIMPMGI:18576262290270 PMID:7903601MGIPMID:7903601
Hoxa2Mousecell fate commitment acts_upstream_of_or_withinIMPMGI:18575302290270 PMID:7903600MGIPMID:7903600
Hoxa2Mousecell fate determination acts_upstream_of_or_withinIMPMGI:23857112290270 PMID:16221728MGIPMID:16221728
Hoxa2Mousecellular response to retinoic acid acts_upstream_of_or_withinIDA 2290270 PMID:23723417MGIPMID:23723417
Hoxa2Mousedorsal/ventral pattern formation acts_upstream_of_or_withinIMPMGI:18576262290270 PMID:10230789MGIPMID:10230789
Hoxa2Mousedorsal/ventral pattern formation acts_upstream_of_or_withinIGIMGI:961832290270 PMID:10230789MGIPMID:10230789
Hoxa2Mouseembryonic skeletal system development involved_inIDA 2290270 PMID:25889273MGIPMID:25889273
Hoxa2Mouseembryonic skeletal system morphogenesis acts_upstream_of_or_withinIGIMGI:1027782290270 PMID:15634706MGIPMID:15634706
Hoxa2Mouseembryonic viscerocranium morphogenesis acts_upstream_of_or_withinIMPMGI:23857112290270 PMID:16221728MGIPMID:16221728
Hoxa2Mousemiddle ear morphogenesis acts_upstream_of_or_withinIMPMGI:23857112290270 PMID:16221728MGIPMID:16221728
Hoxa2Mousemiddle ear morphogenesis acts_upstream_of_or_withinIGIMGI:1027782290270 PMID:15634706MGIPMID:15634706
Hoxa2Mousemiddle ear morphogenesis acts_upstream_of_or_withinIMPMGI:18575302290270 PMID:15861402MGIPMID:15861402
Hoxa2Mousemotor neuron axon guidance acts_upstream_of_or_withinIMPMGI:18576262290270 PMID:9367425MGIPMID:9367425
Hoxa2Mousemuscle structure development involved_inIDA 2290270 PMID:25889273MGIPMID:25889273
Hoxa2Mousenegative regulation of neuron differentiation acts_upstream_of_or_withinIGIMGI:104717 more ...2290270 PMID:18164701MGIPMID:18164701
Hoxa2Mousenegative regulation of neuron differentiation acts_upstream_of_or_withinIMPMGI:18575302290270 PMID:18164701MGIPMID:18164701
Hoxa2Mousenegative regulation of osteoblast differentiation acts_upstream_of_or_withinIDA 2290270 PMID:21324897MGIPMID:21324897
Hoxa2Mousenegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIDA 2290270 PMID:15634706MGIPMID:15634706
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Cellular Component

  
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Original Reference(s)
Hoxa2Mouseintracellular membrane-bounded organelle located_inISOUniProtKB:O433642290270 GO_CentralGO_REF:0000119
Hoxa2Mousenucleoplasm located_inISOUniProtKB:O433642290270 GO_CentralGO_REF:0000119
Hoxa2Mousenucleoplasm located_inTAS 2290270 ReactomeReactome:R-MMU-5619429 and Reactome:R-MMU-9010499
Hoxa2Mousenucleus is_active_inIBAPANTHER:PTN005228379 more ...2290270 GO_CentralGO_REF:0000033
Hoxa2Mousenucleus located_inIDA 2290270 PMID:10536059 and PMID:11209945MGIPMID:10536059 and PMID:11209945

Molecular Function

  

1 to 20 of 157 rows
Object Symbol
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Original Reference(s)
Hoxa2Mouseabnormal auditory brainstem response  IEA 5509061 MGI 
Hoxa2Mouseabnormal basioccipital bone morphology  IAGP 5509061 MGIPMID:7903601
Hoxa2Mouseabnormal basioccipital bone morphology  IAGP 5509061 MGIPMID:7903600
Hoxa2Mouseabnormal basioccipital bone morphology  IAGP 5509061 MGIPMID:10529419
Hoxa2Mouseabnormal basisphenoid bone morphology  IAGP 5509061 MGIPMID:11578867
Hoxa2Mouseabnormal behavior  IAGP 5509061 MGIPMID:11857791
Hoxa2Mouseabnormal behavior  IAGP 5509061 MGIPMID:11857792
Hoxa2Mouseabnormal brain development  IAGP 5509061 MGIPMID:23197710
Hoxa2Mouseabnormal cartilage development  IAGP 5509061 MGIPMID:7903601
Hoxa2Mouseabnormal cochlear VIII nucleus morphology  IAGP 5509061 MGIPMID:23408898
Hoxa2Mouseabnormal craniofacial bone morphology  IAGP 5509061 MGIPMID:16221728
Hoxa2Mouseabnormal craniofacial morphology  IAGP 5509061 MGIPMID:11857791
Hoxa2Mouseabnormal craniofacial morphology  IAGP 5509061 MGIPMID:11857792
Hoxa2Mouseabnormal cranium morphology  IAGP 5509061 MGIPMID:10529419
Hoxa2Mouseabnormal ear morphology  IAGP 5509061 MGIPMID:11857791
Hoxa2Mouseabnormal ear morphology  IAGP 5509061 MGIPMID:11857792
Hoxa2Mouseabnormal external auditory canal morphology  IAGP 5509061 MGIPMID:8565828
Hoxa2Mouseabnormal facial motor nucleus morphology  IAGP 5509061 MGIPMID:7903601
Hoxa2Mouseabnormal facial nerve morphology  IAGP 5509061 MGIPMID:7903601
Hoxa2Mouseabnormal facial nerve morphology  IAGP 5509061 MGIPMID:11578867
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Reference Title
Reference Citation
1. A mutation in HOXA2 is responsible for autosomal-recessive microtia in an Iranian family. Alasti F, etal., Am J Hum Genet. 2008 Apr;82(4):982-91. doi: 10.1016/j.ajhg.2008.02.015.
2. Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia. Collins EC, etal., Mol Cell Biol 2002 Oct;22(20):7313-24.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:1348361   PMID:1352886   PMID:1358459   PMID:1682814   PMID:7508007   PMID:7626396   PMID:7635047   PMID:7743939   PMID:7903600   PMID:7903601   PMID:7956823   PMID:8102800  
PMID:8268652   PMID:8565828   PMID:8625806   PMID:8806819   PMID:8833244   PMID:8898234   PMID:9053316   PMID:9142993   PMID:9337135   PMID:9367423   PMID:9367425   PMID:9449667  
PMID:9636074   PMID:9806922   PMID:10068641   PMID:10230789   PMID:10349636   PMID:10529419   PMID:10536059   PMID:10625532   PMID:10654602   PMID:10662633   PMID:10789828   PMID:11042159  
PMID:11076861   PMID:11209945   PMID:11217851   PMID:11336508   PMID:11532923   PMID:11566859   PMID:11578867   PMID:11748135   PMID:11857791   PMID:11857792   PMID:12027433   PMID:12086465  
PMID:12367504   PMID:12412013   PMID:12412017   PMID:12466851   PMID:12477932   PMID:12514106   PMID:12676559   PMID:12702665   PMID:12736208   PMID:12810588   PMID:14651926   PMID:14681479  
PMID:14960494   PMID:14975722   PMID:15033486   PMID:15042701   PMID:15326611   PMID:15489334   PMID:15618518   PMID:15634706   PMID:15652707   PMID:15680324   PMID:15680353   PMID:15680361  
PMID:15790971   PMID:15861402   PMID:15936338   PMID:16141072   PMID:16141073   PMID:16221728   PMID:16515781   PMID:16602821   PMID:16651541   PMID:16751105   PMID:16902088   PMID:16971476  
PMID:17113575   PMID:17166916   PMID:17359301   PMID:17586487   PMID:17652354   PMID:17676642   PMID:17687036   PMID:17728342   PMID:17804628   PMID:17897445   PMID:18164701   PMID:18216176  
PMID:18287559   PMID:18321982   PMID:18417536   PMID:18547144   PMID:18787068   PMID:18930042   PMID:19104046   PMID:19168678   PMID:19204410   PMID:19653318   PMID:19655241   PMID:19716816  
PMID:19922872   PMID:20034726   PMID:20059953   PMID:20206242   PMID:20211142   PMID:20501333   PMID:20651846   PMID:20809987   PMID:20932939   PMID:20969845   PMID:21149574   PMID:21245383  
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Hoxa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,139,389 - 52,141,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,139,397 - 52,141,811 (-)EnsemblGRCm39 Ensembl
GRCm38652,162,417 - 52,164,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,162,417 - 52,164,831 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,112,510 - 52,114,830 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,092,094 - 52,094,414 (-)NCBIMGSCv36mm8
Celera652,684,174 - 52,686,494 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
HOXA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,100,354 - 27,102,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,100,354 - 27,102,686 (-)EnsemblGRCh38hg38GRCh38
GRCh37727,139,973 - 27,142,302 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,106,498 - 27,108,919 (-)NCBINCBI36Build 36hg18NCBI36
Build 34726,913,213 - 26,915,634NCBI
Celera727,128,910 - 27,131,331 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,020,564 - 27,022,985 (-)NCBIHuRef
CHM1_1727,139,670 - 27,142,091 (-)NCBICHM1_1
T2T-CHM13v2.0727,236,253 - 27,238,582 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,191,126 - 27,193,547 (-)NCBI
Hoxa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,593,389 - 82,597,589 (-)NCBIGRCr8
mRatBN7.2481,262,668 - 81,266,970 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,262,768 - 81,265,044 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0482,130,441 - 82,134,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,131,329 - 82,133,605 (-)EnsemblRnor6.0rn6Rnor6.0
Celera476,153,207 - 76,157,522 (-)NCBICelera
Cytogenetic Map4q24NCBI
Hoxa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,794,878 - 28,798,231 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,794,878 - 28,798,231 (-)NCBIChiLan1.0ChiLan1.0
HOXA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,929,398 - 31,933,844 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,250,959 - 80,256,546 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,745,138 - 27,747,129 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,344,100 - 27,346,794 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,344,469 - 27,346,789 (-)Ensemblpanpan1.1panPan2
HOXA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,273,992 - 40,276,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,274,469 - 40,276,239 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,705,487 - 39,708,305 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,213,194 - 40,216,016 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,213,230 - 40,215,000 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,327,306 - 40,330,123 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,012,375 - 40,015,186 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,370,952 - 40,373,773 (-)NCBIUU_Cfam_GSD_1.0
Hoxa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,516,906 - 84,520,094 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,729,107 - 3,730,870 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,729,079 - 3,731,353 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,470,862 - 45,473,876 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,470,079 - 45,473,345 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,103,242 - 50,106,499 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,261,992 - 31,271,071 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,266,459 - 31,268,221 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,462,800 - 73,471,020 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,501,817 - 3,504,750 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247393,501,671 - 3,504,939 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Hoxa2
72 total Variants

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:79
Interacting mature miRNAs:79
Transcripts:ENSMUST00000014848
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
14696807Rbcn2_mrod bipolar cell number 2 (mouse)65118698056186985Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse

1 to 10 of 51 rows
Hoxa9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37652,174,170 - 52,175,566UniSTSGRCm37
MGSCv37652,173,711 - 52,174,277UniSTSGRCm37
MGSCv37652,176,430 - 52,177,278UniSTSGRCm37
MGSCv37652,174,279 - 52,175,574UniSTSGRCm37
MGSCv37652,174,406 - 52,175,954UniSTSGRCm37
MGSCv37652,174,722 - 52,174,858UniSTSGRCm37
Celera652,746,362 - 52,746,498UniSTS
Celera652,745,919 - 52,747,214UniSTS
Celera652,746,046 - 52,747,594UniSTS
Celera652,745,351 - 52,745,917UniSTS
Celera652,748,070 - 52,748,918UniSTS
Celera652,745,810 - 52,747,206UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.32UniSTS
cM Map626.32UniSTS
cM Map626.29UniSTS
cM Map626.32UniSTS
cM Map626.32UniSTS
M95599  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,162,603 - 52,162,766UniSTSGRCm38
MGSCv37652,112,602 - 52,112,765UniSTSGRCm37
Celera652,684,266 - 52,684,429UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
Whitehead_YAC6 UniSTS
AI324701  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,163,396 - 52,163,479UniSTSGRCm38
MGSCv37652,113,395 - 52,113,478UniSTSGRCm37
Celera652,685,059 - 52,685,142UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
ECD09887  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,164,482 - 52,165,103UniSTSGRCm38
MGSCv37652,114,481 - 52,115,102UniSTSGRCm37
Celera652,686,145 - 52,686,766UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
REN100339  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,164,569 - 52,164,808UniSTSGRCm38
MGSCv37652,114,568 - 52,114,807UniSTSGRCm37
Celera652,686,232 - 52,686,471UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
REN100338  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,164,336 - 52,164,590UniSTSGRCm38
MGSCv37652,114,335 - 52,114,589UniSTSGRCm37
Celera652,685,999 - 52,686,253UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
ECD00644  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,163,387 - 52,164,279UniSTSGRCm38
MGSCv37652,113,386 - 52,114,278UniSTSGRCm37
Celera652,685,050 - 52,685,942UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
Hoxa2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,163,130 - 52,163,280UniSTSGRCm38
MGSCv37652,113,129 - 52,113,279UniSTSGRCm37
Celera652,684,793 - 52,684,943UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
Hoxa2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,161,725 - 52,161,884UniSTSGRCm38
MGSCv37652,111,724 - 52,111,883UniSTSGRCm37
Celera652,683,362 - 52,683,535UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS
Hoxa2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6B3UniSTS
cM Map626.29UniSTS






1 to 21 of 21 rows
RefSeq Transcripts NM_010451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB039184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB221621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M87801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M93148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M93292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M95599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 21 of 21 rows

Ensembl Acc Id: ENSMUST00000014848   ⟹   ENSMUSP00000014848
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,139,397 - 52,141,811 (-)Ensembl
GRCm38.p6 Ensembl652,162,417 - 52,164,831 (-)Ensembl
RefSeq Acc Id: NM_010451   ⟹   NP_034581
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39652,139,389 - 52,141,808 (-)NCBI
GRCm38652,162,417 - 52,164,831 (-)NCBI
MGSCv37652,112,510 - 52,114,830 (-)RGD
Celera652,684,080 - 52,686,494 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034581   ⟸   NM_010451
- UniProtKB: Q149U3 (UniProtKB/Swiss-Prot),   Q920T8 (UniProtKB/Swiss-Prot),   P31245 (UniProtKB/Swiss-Prot),   Q3UYP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000014848   ⟸   ENSMUST00000014848
Homeobox

Name Modeler Protein Id AA Range Protein Structure
AF-P31245-F1-model_v2 AlphaFold P31245 1-372 view protein structure

RGD ID:6839454
Promoter ID:MM_KWN:45999
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   Lung
Transcripts:OTTMUST00000045381
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36652,114,296 - 52,114,796 (-)MPROMDB
RGD ID:6889720
Promoter ID:EPDNEW_M8311
Type:multiple initiation site
Name:Hoxa2_1
Description:Mus musculus homeobox A2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38652,164,828 - 52,164,888EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000014704 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000014848 ENTREZGENE
  ENSMUST00000014848.11 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_Antennapedia_CS UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Homeobox_metazoa UniProtKB/Swiss-Prot
KEGG Report mmu:15399 UniProtKB/Swiss-Prot
MGD MGI:96174 ENTREZGENE
NCBI Gene 15399 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-A2 UniProtKB/Swiss-Prot
  PROTEIN ZERKNUELLT 1-RELATED UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
PhenoGen Hoxa2 PhenoGen
PRINTS HOMEOBOX UniProtKB/Swiss-Prot
PROSITE ANTENNAPEDIA UniProtKB/Swiss-Prot
  HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
UniProt HXA2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q149U3 ENTREZGENE
  Q3UYP9 ENTREZGENE, UniProtKB/TrEMBL
  Q920T8 ENTREZGENE
UniProt Secondary Q149U3 UniProtKB/Swiss-Prot
  Q920T8 UniProtKB/Swiss-Prot
1 to 28 of 28 rows