HOXA2 (homeobox A2) - Rat Genome Database

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Gene: HOXA2 (homeobox A2) Canis lupus familiaris
Analyze
Symbol: HOXA2
Name: homeobox A2
RGD ID: 12261536
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN anterior/posterior pattern specification (ortholog); brain segmentation (ortholog); cell fate commitment (ortholog); ASSOCIATED WITH Athabaskan brainstem dysgenesis syndrome (ortholog); Congenital Microtia (ortholog); genetic disease (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein Hox-A2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,273,992 - 40,276,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,274,469 - 40,276,239 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,705,487 - 39,708,305 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,213,194 - 40,216,016 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,213,230 - 40,215,000 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,327,306 - 40,330,123 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,012,375 - 40,015,186 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,370,952 - 40,373,773 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
HOXA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,273,992 - 40,276,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,274,469 - 40,276,239 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,705,487 - 39,708,305 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,213,194 - 40,216,016 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,213,230 - 40,215,000 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,327,306 - 40,330,123 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,012,375 - 40,015,186 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,370,952 - 40,373,773 (-)NCBIUU_Cfam_GSD_1.0
HOXA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,100,354 - 27,102,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,100,354 - 27,102,686 (-)EnsemblGRCh38hg38GRCh38
GRCh37727,139,973 - 27,142,302 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,106,498 - 27,108,919 (-)NCBINCBI36Build 36hg18NCBI36
Build 34726,913,213 - 26,915,634NCBI
Celera727,128,910 - 27,131,331 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,020,564 - 27,022,985 (-)NCBIHuRef
CHM1_1727,139,670 - 27,142,091 (-)NCBICHM1_1
T2T-CHM13v2.0727,236,253 - 27,238,582 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,191,126 - 27,193,547 (-)NCBI
Hoxa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,139,389 - 52,141,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,139,397 - 52,141,811 (-)EnsemblGRCm39 Ensembl
GRCm38652,162,417 - 52,164,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,162,417 - 52,164,831 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,112,510 - 52,114,830 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,092,094 - 52,094,414 (-)NCBIMGSCv36mm8
Celera652,684,174 - 52,686,494 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
Hoxa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,593,389 - 82,597,589 (-)NCBIGRCr8
mRatBN7.2481,262,668 - 81,266,970 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,262,768 - 81,265,044 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0482,130,441 - 82,134,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,131,329 - 82,133,605 (-)EnsemblRnor6.0rn6Rnor6.0
Celera476,153,207 - 76,157,522 (-)NCBICelera
Cytogenetic Map4q24NCBI
Hoxa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,794,878 - 28,798,231 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,794,878 - 28,798,231 (-)NCBIChiLan1.0ChiLan1.0
HOXA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,929,398 - 31,933,844 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,250,959 - 80,256,546 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,745,138 - 27,747,129 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,344,100 - 27,346,794 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,344,469 - 27,346,789 (-)Ensemblpanpan1.1panPan2
Hoxa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,516,906 - 84,520,094 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,729,107 - 3,730,870 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,729,079 - 3,731,353 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,470,862 - 45,473,876 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,470,079 - 45,473,345 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,103,242 - 50,106,499 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,261,992 - 31,271,071 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,266,459 - 31,268,221 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,462,800 - 73,471,020 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,501,817 - 3,504,750 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247393,501,671 - 3,504,939 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HOXA2
6 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 1 18 19 15 5 3 5 6 25 15 7 9 10

Sequence


Ensembl Acc Id: ENSCAFT00000004713   ⟹   ENSCAFP00000004363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1440,274,469 - 40,276,239 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845020038   ⟹   ENSCAFP00845015700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1440,213,230 - 40,215,000 (-)Ensembl
RefSeq Acc Id: XM_038494895   ⟹   XP_038350823
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11440,327,306 - 40,330,123 (-)NCBI
RefSeq Acc Id: XM_038557170   ⟹   XP_038413098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01440,370,952 - 40,373,773 (-)NCBI
RefSeq Acc Id: XM_038621109   ⟹   XP_038477037
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01440,012,375 - 40,015,186 (-)NCBI
RefSeq Acc Id: XM_038686785   ⟹   XP_038542713
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01440,213,194 - 40,216,016 (-)NCBI
RefSeq Acc Id: XM_846812   ⟹   XP_851905
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11440,273,992 - 40,276,975 (-)NCBI
Dog10K_Boxer_Tasha1439,705,487 - 39,708,305 (-)NCBI
Sequence:
RefSeq Acc Id: XP_851905   ⟸   XM_846812
- UniProtKB: A0A8C0JRR3 (UniProtKB/TrEMBL),   A0A8C0RDE8 (UniProtKB/TrEMBL),   A0A8I3NDA0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000004363   ⟸   ENSCAFT00000004713
RefSeq Acc Id: XP_038350823   ⟸   XM_038494895
RefSeq Acc Id: XP_038477037   ⟸   XM_038621109
RefSeq Acc Id: XP_038542713   ⟸   XM_038686785
- UniProtKB: A0A8C0JRR3 (UniProtKB/TrEMBL),   A0A8C0RDE8 (UniProtKB/TrEMBL),   A0A8I3NDA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038413098   ⟸   XM_038557170
- UniProtKB: A0A8C0JRR3 (UniProtKB/TrEMBL),   A0A8C0RDE8 (UniProtKB/TrEMBL),   A0A8I3NDA0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845015700   ⟸   ENSCAFT00845020038
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002942 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005576 UniProtKB/TrEMBL
  ENSCAFG00040009662 UniProtKB/TrEMBL
  ENSCAFG00845011307 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004713.6 UniProtKB/TrEMBL
  ENSCAFT00030010204.1 UniProtKB/TrEMBL
  ENSCAFT00040017904.1 UniProtKB/TrEMBL
  ENSCAFT00845020038 ENTREZGENE
  ENSCAFT00845020038.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_Antennapedia_CS UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
KEGG Report cfa:609592 UniProtKB/TrEMBL
NCBI Gene HOXA2 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-A2 UniProtKB/TrEMBL
  PROTEIN ZERKNUELLT 1-RELATED UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
PROSITE ANTENNAPEDIA UniProtKB/TrEMBL
  HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C0JRR3 ENTREZGENE
  A0A8C0RDE8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NDA0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54768 ENTREZGENE