Synj2_v2 (synaptojanin 2, variant 2) - Rat Genome Database

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Gene: Synj2_v2 (synaptojanin 2, variant 2) Rattus norvegicus
Symbol: Synj2_v2
Name: synaptojanin 2, variant 2
RGD ID: 728906
Description: variant of synaptojanin 2; this isoform binds amphiphysin but not endophilin
FOUND IN axon terminus; cytoplasmic microtubule; ruffle membrane
Type: splice  of Synj2  
Previously known as: synaptojanin 2B1; Synj2B1
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
RGSC_v3.1140,766,738 - 40,820,945 (+)NCBI

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function


References - curated
# Reference Title Reference Citation
1. Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals. Nemoto Y, etal., J Biol Chem 2001 Nov 2;276(44):41133-42.




Nucleotide Sequences
GenBank Nucleotide AY034050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Additional Information

Database Acc Id Source(s)
BIND 130420

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-09-02 Synj2_v2  synaptojanin 2, variant 2  Synj2_v2  synaptojanin 2, varient 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Synj2_v2  synaptojanin 2, varient 2    synaptojanin 2, variant 2  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains an endophilin-binding motif 628465
gene_expression expressed at nerve terminals in brain and at the spermatid manchette in testis 628465
gene_physical_interaction binds to amphiphysin but not endophilin 628465
gene_protein contains an extra 46-amino acid sequence at the C-terminal region when compared to the Synj2_v2 (2B1) 628465
gene_protein missing a 46-amino acid sequence at the C-terminal region when compared to the Synj2_v3 (2B2) 628465
gene_protein 1451 amino acids with predicted molecular weight of 160 kDa 628465