Gene: Brca2m1Uwm (BRCA2, DNA repair associated; mutation 1, University of Wisconsin-Madison) Rattus norvegicus
Symbol: Brca2m1Uwm
Name: BRCA2, DNA repair associated; mutation 1, University of Wisconsin-Madison
Description: produced by N-ethyl-N-nitrosourea (ENU)-induced germline mutations in Sprague Dawley (SD) rats; nonsense transversion mutation at nucleotide T4254 that converted TAT (tyrosine) to TAA (stop codon)
ASSOCIATED WITH decreased body weight; ovary atrophy; testicular atrophy; ASSOCIATED WITH infertility
Type: allele  of Brca2  
Also known as: Brca2m1Uwm; Brca2m1Uwm
Is Marker For: Strains:   SD-Brca2m1Uwm  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
RGSC_v3.1124,282,951 - 4,323,693 (-)NCBI

Disease Annotations
Phenotype Annotations
References - curated
RGD Disease Portals


Related Rat Strains


Nucleotide Sequences

Additional Information

Nomenclature History
RGD Curation Notes
More on Brca2m1Uwm
Alliance Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 728326
Created: 2003-11-13
Species: Rattus norvegicus
Last Modified: 2004-12-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.