FER1L6-AS2 (FER1L6 antisense RNA 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: FER1L6-AS2 (FER1L6 antisense RNA 2) Homo sapiens
Analyze
Symbol: FER1L6-AS2
Name: FER1L6 antisense RNA 2
RGD ID: 7246874
HGNC Page HGNC
Description:
Type: ncrna
RefSeq Status: PREDICTED
Also known as: C8orf78; RP11-959I15.3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8124,044,395 - 124,171,522 (-)EnsemblGRCh38hg38GRCh38
GRCh388124,046,071 - 124,171,522 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378125,058,312 - 125,183,763 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map8q24.13NCBI
HuRef8120,385,076 - 120,510,689 (-)NCBIHuRef
CHM1_18125,098,618 - 125,224,125 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
1. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334  


Genomics

Position Markers
D8S2064  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378125,131,449 - 125,131,673UniSTSGRCh37
Build 368125,200,630 - 125,200,854RGDNCBI36
Celera8121,319,557 - 121,319,781RGD
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map8q24.1UniSTS
HuRef8120,458,137 - 120,458,361UniSTS
RH92138  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378125,070,835 - 125,070,978UniSTSGRCh37
Build 368125,140,016 - 125,140,159RGDNCBI36
Celera8121,258,864 - 121,259,007RGD
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map8q24.1UniSTS
HuRef8120,397,598 - 120,397,741UniSTS
GeneMap99-GB4 RH Map8476.51UniSTS
SHGC-81177  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378125,102,256 - 125,102,562UniSTSGRCh37
Build 368125,171,437 - 125,171,743RGDNCBI36
Celera8121,290,291 - 121,290,597RGD
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map8q24.1UniSTS
HuRef8120,428,910 - 120,429,216UniSTS
TNG Radiation Hybrid Map860302.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:96
Interacting mature miRNAs:99
Transcripts:ENST00000520031, ENST00000601180
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 2 36 1
Low 13 16 11 10 11 5 5 657 1 341 6 1 1
Below cutoff 475 351 576 50 199 32 469 309 1975 86 164 472 23 77 316 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000520031
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8124,046,073 - 124,171,522 (-)Ensembl
RefSeq Acc Id: ENST00000661827
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8124,058,537 - 124,171,451 (-)Ensembl
RefSeq Acc Id: ENST00000669903
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8124,044,395 - 124,171,473 (-)Ensembl
RefSeq Acc Id: NR_103547
RefSeq Status: PREDICTED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388124,046,071 - 124,171,522 (-)NCBI
HuRef8120,385,076 - 120,510,689 (-)NCBI
CHM1_18125,098,618 - 125,224,125 (-)NCBI
Sequence:
Protein Sequences
GenBank Protein BAB71431 (Get FASTA)   NCBI Sequence Viewer  
  EAW92056 (Get FASTA)   NCBI Sequence Viewer  
  EAW92057 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences

Promoters
RGD ID:15096280
Promoter ID:EPDNEWNC_H1096
Type:initiation region
Name:FER1L6-AS2_1
Description:FER1L6 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:26534]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388124,171,529 - 124,171,589EPDNEWNC

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001039112.2(FER1L6):c.3084C>T (p.Ser1028=) single nucleotide variant Malignant melanoma [RCV000061748] Chr8:124060646 [GRCh38]
Chr8:125072887 [GRCh37]
Chr8:125142068 [NCBI36]
Chr8:8q24.13
not provided
NM_001039112.2(FER1L6):c.3659C>T (p.Ser1220Phe) single nucleotide variant Malignant melanoma [RCV000061749] Chr8:124066531 [GRCh38]
Chr8:125078772 [GRCh37]
Chr8:125147953 [NCBI36]
Chr8:8q24.13
not provided
NM_001039112.2(FER1L6):c.3997G>A (p.Asp1333Asn) single nucleotide variant Malignant melanoma [RCV000061750] Chr8:124071536 [GRCh38]
Chr8:125083777 [GRCh37]
Chr8:125152958 [NCBI36]
Chr8:8q24.13
not provided
NM_001039112.2(FER1L6):c.3293C>T (p.Pro1098Leu) single nucleotide variant Malignant melanoma [RCV000068143] Chr8:124061997 [GRCh38]
Chr8:125074238 [GRCh37]
Chr8:125143419 [NCBI36]
Chr8:8q24.13
not provided
NM_001039112.2(FER1L6):c.4303G>T (p.Asp1435Tyr) single nucleotide variant Malignant melanoma [RCV000068144] Chr8:124082370 [GRCh38]
Chr8:125094611 [GRCh37]
Chr8:125163792 [NCBI36]
Chr8:8q24.13
not provided
NM_001039112.2(FER1L6):c.4365C>T (p.Ile1455=) single nucleotide variant Malignant melanoma [RCV000068145] Chr8:124082432 [GRCh38]
Chr8:125094673 [GRCh37]
Chr8:125163854 [NCBI36]
Chr8:8q24.13
not provided
GRCh38/hg38 8q24.13-24.21(chr8:122454392-128513076)x3 copy number gain See cases [RCV000133620] Chr8:122454392..128513076 [GRCh38]
Chr8:123466631..129525322 [GRCh37]
Chr8:123535812..129594504 [NCBI36]
Chr8:8q24.13-24.21
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:103306336-145068712)x3 copy number gain See cases [RCV000142810] Chr8:103306336..145068712 [GRCh38]
Chr8:104318564..146294098 [GRCh37]
Chr8:104387740..146264902 [NCBI36]
Chr8:8q22.3-24.3
pathogenic|likely pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q23.3-24.3(chr8:113580402-145054634)x3 copy number gain See cases [RCV000050638] Chr8:113580402..145054634 [GRCh38]
Chr8:114592631..146280020 [GRCh37]
Chr8:114661807..146250824 [NCBI36]
Chr8:8q23.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q24.13(chr8:124125245-125337217)x3 copy number gain See cases [RCV000050762] Chr8:124125245..125337217 [GRCh38]
Chr8:125137486..126349459 [GRCh37]
Chr8:125206667..126418641 [NCBI36]
Chr8:8q24.13
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q23.3-24.21(chr8:113288454-126716087)x1 copy number loss See cases [RCV000054301] Chr8:113288454..126716087 [GRCh38]
Chr8:114300683..127728332 [GRCh37]
Chr8:114369859..127797514 [NCBI36]
Chr8:8q23.3-24.21
pathogenic
NM_001039112.2(FER1L6):c.4344C>T (p.Phe1448=) single nucleotide variant not provided [RCV000947134] Chr8:124082411 [GRCh38]
Chr8:125094652 [GRCh37]
Chr8:8q24.13
benign
NM_001039112.2(FER1L6):c.4089C>T (p.Val1363=) single nucleotide variant not provided [RCV000947133] Chr8:124071628 [GRCh38]
Chr8:125083869 [GRCh37]
Chr8:8q24.13
benign
NM_001039112.2(FER1L6):c.2781C>T (p.Asp927=) single nucleotide variant not provided [RCV000915761] Chr8:124049663 [GRCh38]
Chr8:125061904 [GRCh37]
Chr8:8q24.13
likely benign
NM_001039112.2(FER1L6):c.2827G>T (p.Gly943Trp) single nucleotide variant not provided [RCV000923690] Chr8:124049709 [GRCh38]
Chr8:125061950 [GRCh37]
Chr8:8q24.13
benign
NM_001039112.2(FER1L6):c.2961G>A (p.Pro987=) single nucleotide variant not provided [RCV000920431] Chr8:124060266 [GRCh38]
Chr8:125072507 [GRCh37]
Chr8:8q24.13
likely benign
NM_001039112.2(FER1L6):c.4908C>T (p.Asp1636=) single nucleotide variant not provided [RCV000964135] Chr8:124101121 [GRCh38]
Chr8:125113362 [GRCh37]
Chr8:8q24.13
benign
NM_001039112.2(FER1L6):c.2981T>G (p.Val994Gly) single nucleotide variant not provided [RCV000949531] Chr8:124060286 [GRCh38]
Chr8:125072527 [GRCh37]
Chr8:8q24.13
likely benign
NM_001039112.2(FER1L6):c.4236A>G (p.Gln1412=) single nucleotide variant not provided [RCV000892918] Chr8:124082303 [GRCh38]
Chr8:125094544 [GRCh37]
Chr8:8q24.13
benign
NM_001039112.2(FER1L6):c.3328G>A (p.Asp1110Asn) single nucleotide variant not provided [RCV000889700] Chr8:124062032 [GRCh38]
Chr8:125074273 [GRCh37]
Chr8:8q24.13
benign

Additional Information

Database Acc Id Source(s)
COSMIC FER1L6-AS2 COSMIC
Ensembl Genes ENSG00000253868 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000520031 ENTREZGENE
GTEx ENSG00000253868 GTEx
HGNC ID HGNC:26534 ENTREZGENE
Human Proteome Map FER1L6-AS2 Human Proteome Map
NCBI Gene FER1L6-AS2 ENTREZGENE
PharmGKB PA143485342 PharmGKB
RNAcentral URS0000759E35 RNACentral
UniProt FEAS2_HUMAN UniProtKB/Swiss-Prot