P2ry4 (pyrimidinergic receptor P2Y4) - Rat Genome Database

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Gene: P2ry4 (pyrimidinergic receptor P2Y4) Rattus norvegicus
Analyze
Symbol: P2ry4
Name: pyrimidinergic receptor P2Y4
RGD ID: 61798
Description: Enables ATP binding activity. Involved in regulation of presynaptic cytosolic calcium ion concentration and regulation of synaptic vesicle exocytosis. Located in apical plasma membrane and basolateral plasma membrane. Is active in glutamatergic synapse and presynaptic active zone membrane. Orthologous to human P2RY4 (pyrimidinergic receptor P2Y4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: P2Y ATP receptor 4; P2Y purinoceptor 4; P2Y4; purinergic receptor P2Y G-protein coupled 4; purinergic receptor P2Y, G-protein coupled 4; pyrimidinergic receptor P2Y G-protein coupled 4; pyrimidinergic receptor P2Y, G-protein coupled, 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X65,681,680 - 65,717,404 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX65,683,232 - 65,721,748 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX67,170,441 - 67,171,854 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X70,670,833 - 70,672,246 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X68,231,732 - 68,233,145 (-)NCBIRnor_WKY
Rnor_6.0X70,421,599 - 70,447,109 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX70,426,951 - 70,428,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X71,296,545 - 71,329,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,589,534 - 88,590,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X88,662,966 - 88,664,380 (-)NCBI
CeleraX66,045,899 - 66,047,312 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular cloning and characterization of rat P2Y4 nucleotide receptor. Bogdanov YD, etal., Br J Pharmacol 1998 Jun;124(3):428-30.
2. Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia. Dranoff JA, etal., Am J Physiol Gastrointest Liver Physiol 2001 Oct;281(4):G1059-67.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. Rodrigues RJ, etal., J Neurosci. 2005 Jul 6;25(27):6286-95.
10. Molecular cloning and characterization of the mouse P2Y4 nucleotide receptor. Suarez-Huerta N, etal., Eur J Pharmacol 2001 Mar 30;416(3):197-202.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:9751165   PMID:11259526   PMID:12850289   PMID:14564529   PMID:14764443   PMID:16075244   PMID:17433586   PMID:18216148   PMID:18625291   PMID:19191015   PMID:19244398   PMID:21300137  
PMID:23479225   PMID:24771361   PMID:28468962   PMID:33122160   PMID:36591760  


Genomics

Comparative Map Data
P2ry4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X65,681,680 - 65,717,404 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX65,683,232 - 65,721,748 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX67,170,441 - 67,171,854 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X70,670,833 - 70,672,246 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X68,231,732 - 68,233,145 (-)NCBIRnor_WKY
Rnor_6.0X70,421,599 - 70,447,109 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX70,426,951 - 70,428,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X71,296,545 - 71,329,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,589,534 - 88,590,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X88,662,966 - 88,664,380 (-)NCBI
CeleraX66,045,899 - 66,047,312 (-)NCBICelera
Cytogenetic MapXq22NCBI
P2RY4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X70,258,166 - 70,260,204 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX70,258,166 - 70,260,204 (-)EnsemblGRCh38hg38GRCh38
GRCh37X69,478,016 - 69,480,054 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,394,741 - 69,396,379 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X69,261,247 - 69,262,675NCBI
CeleraX69,831,353 - 69,832,991 (-)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX63,299,114 - 63,300,752 (-)NCBIHuRef
CHM1_1X69,371,994 - 69,373,632 (-)NCBICHM1_1
T2T-CHM13v2.0X68,691,490 - 68,693,528 (-)NCBIT2T-CHM13v2.0
P2ry4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X99,631,964 - 99,638,533 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX99,633,760 - 99,638,475 (-)EnsemblGRCm39 Ensembl
GRCm38X100,588,358 - 100,594,927 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX100,590,154 - 100,594,869 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X97,785,493 - 97,790,208 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X96,792,873 - 96,797,588 (-)NCBIMGSCv36mm8
CeleraX87,516,188 - 87,520,903 (-)NCBICelera
Cytogenetic MapXC3NCBI
P2ry4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554759,800,541 - 9,802,055 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554759,794,538 - 9,802,055 (-)NCBIChiLan1.0ChiLan1.0
P2RY4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1X69,939,413 - 69,940,510 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X59,526,621 - 59,528,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X69,585,984 - 69,587,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX69,586,340 - 69,587,437 (-)Ensemblpanpan1.1panPan2
P2RY4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X54,706,404 - 54,707,512 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX45,532,412 - 45,533,520 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X55,672,553 - 55,673,661 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X53,641,532 - 53,642,640 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X54,972,339 - 54,973,447 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X54,899,511 - 54,900,619 (-)NCBIUU_Cfam_GSD_1.0
P2ry4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X47,455,684 - 47,457,937 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367621,217,858 - 1,218,950 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049367621,217,858 - 1,218,948 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RY4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX56,279,346 - 56,286,400 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X56,284,736 - 56,285,833 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X63,479,522 - 63,480,619 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P2RY4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,099,961 - 60,104,094 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX60,102,265 - 60,103,362 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660651,948,078 - 1,950,108 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
P2ry4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624903223,520 - 259,111 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624903221,985 - 257,903 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in P2ry4
107 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:66
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000045907
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5
Low 3 37 39 23 19 23 3 3 74 33 34 11 3
Below cutoff 5 18 18 18 5 8 2 2 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC141377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000045907   ⟹   ENSRNOP00000039027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX65,686,252 - 65,721,748 (-)Ensembl
Rnor_6.0 EnsemblX70,426,951 - 70,428,364 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096316   ⟹   ENSRNOP00000094459
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX65,683,232 - 65,721,748 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099755   ⟹   ENSRNOP00000085052
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX65,686,252 - 65,721,604 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112073   ⟹   ENSRNOP00000082634
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX65,683,232 - 65,721,748 (-)Ensembl
RefSeq Acc Id: NM_031680   ⟹   NP_113868
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,687,032 - 65,688,445 (-)NCBI
Rnor_6.0X70,426,951 - 70,428,364 (-)NCBI
Rnor_5.0X71,296,545 - 71,329,324 (-)NCBI
RGSC_v3.4X88,589,534 - 88,590,947 (-)RGD
CeleraX66,045,899 - 66,047,312 (-)RGD
Sequence:
RefSeq Acc Id: XM_039100004   ⟹   XP_038955932
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,707,199 (-)NCBI
RefSeq Acc Id: XM_039100005   ⟹   XP_038955933
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,705,437 (-)NCBI
RefSeq Acc Id: XM_039100006   ⟹   XP_038955934
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,707,199 (-)NCBI
RefSeq Acc Id: XM_039100007   ⟹   XP_038955935
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100008   ⟹   XP_038955936
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100009   ⟹   XP_038955937
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100010   ⟹   XP_038955938
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100011   ⟹   XP_038955939
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100012   ⟹   XP_038955940
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100013   ⟹   XP_038955941
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,707,199 (-)NCBI
RefSeq Acc Id: XM_039100014   ⟹   XP_038955942
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,382 (-)NCBI
RefSeq Acc Id: XM_039100015   ⟹   XP_038955943
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,681,680 - 65,717,404 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_113868   ⟸   NM_031680
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000039027   ⟸   ENSRNOT00000045907
RefSeq Acc Id: XP_038955943   ⟸   XM_039100015
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955940   ⟸   XM_039100012
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955938   ⟸   XM_039100010
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955937   ⟸   XM_039100009
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955942   ⟸   XM_039100014
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955939   ⟸   XM_039100011
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955936   ⟸   XM_039100008
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955935   ⟸   XM_039100007
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955941   ⟸   XM_039100013
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955934   ⟸   XM_039100006
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955932   ⟸   XM_039100004
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038955933   ⟸   XM_039100005
- Peptide Label: isoform X1
- UniProtKB: O35811 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000085052   ⟸   ENSRNOT00000099755
RefSeq Acc Id: ENSRNOP00000082634   ⟸   ENSRNOT00000112073
RefSeq Acc Id: ENSRNOP00000094459   ⟸   ENSRNOT00000096316

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35811-F1-model_v2 AlphaFold O35811 1-361 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61798 AgrOrtholog
BioCyc Gene G2FUF-2130 BioCyc
Ensembl Genes ENSRNOG00000002953 Ensembl
  ENSRNOG00000070777 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000039027 ENTREZGENE
  ENSRNOP00000039027.2 UniProtKB/Swiss-Prot
  ENSRNOP00000082634 ENTREZGENE
  ENSRNOP00000082634.1 UniProtKB/Swiss-Prot
  ENSRNOP00000085052.1 UniProtKB/Swiss-Prot
  ENSRNOP00000094459 ENTREZGENE
  ENSRNOP00000094459.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000045907 ENTREZGENE
  ENSRNOT00000045907.3 UniProtKB/Swiss-Prot
  ENSRNOT00000096316 ENTREZGENE
  ENSRNOT00000096316.1 UniProtKB/Swiss-Prot
  ENSRNOT00000099755.1 UniProtKB/Swiss-Prot
  ENSRNOT00000112073 ENTREZGENE
  ENSRNOT00000112073.1 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  P2Y4 UniProtKB/Swiss-Prot
KEGG Report rno:63843 UniProtKB/Swiss-Prot
NCBI Gene 63843 ENTREZGENE
PANTHER PTHR24231:SF21 UniProtKB/Swiss-Prot
  PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen P2ry4 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  P2Y4PRNOCPTR UniProtKB/Swiss-Prot
  P2YPURNOCPTR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
TIGR TC202238
UniProt O35811 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 P2ry4  pyrimidinergic receptor P2Y4  P2ry4  pyrimidinergic receptor P2Y, G-protein coupled, 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 P2ry4  pyrimidinergic receptor P2Y, G-protein coupled, 4    purinergic receptor P2Y, G-protein coupled 4  Name updated 1299863 APPROVED
2002-06-10 P2ry4  purinergic receptor P2Y, G-protein coupled 4      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the apical plasma membrane and basolateral domains 628452
gene_expression mRNA present in holangiocytes, hepatocytes and epithelial cells 628452
gene_process may mediate vasomotor responses, neurotransmission, platelet aggregation, and secretion 628452
gene_regulation receptor activity is suramin-insensitive 628452