PAM16 (presequence translocase associated motor 16) - Rat Genome Database

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Gene: PAM16 (presequence translocase associated motor 16) Pan paniscus
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Symbol: PAM16 (Ensembl: CORO7)
Name: presequence translocase associated motor 16 (Ensembl:coronin 7)
RGD ID: 32731473
Description: ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN DNA biosynthetic process (ortholog); negative regulation of apoptotic DNA fragmentation (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH epilepsy (ortholog); idiopathic generalized epilepsy (ortholog); Kohlschutter-Tonz syndrome (ortholog); FOUND IN matrix side of mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); PAM complex, Tim23 associated import motor (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC117976183; mitochondrial import inner membrane translocase subunit TIM16; nascent polypeptide-associated complex subunit alpha, muscle-specific form-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,847,319 - 4,883,025 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,631,732 - 8,675,724 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,243,435 - 3,248,815 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl164,418,006 - 4,515,038 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PAM16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,847,319 - 4,883,025 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,631,732 - 8,675,724 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,243,435 - 3,248,815 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl164,418,006 - 4,515,038 (-)Ensemblpanpan1.1panPan2
PAM16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,340,251 - 4,351,321 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,331,549 - 4,355,607 (-)EnsemblGRCh38hg38GRCh38
GRCh37164,390,252 - 4,401,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,330,253 - 4,341,301 (-)NCBINCBI36Build 36hg18NCBI36
Celera164,597,200 - 4,610,208 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,357,104 - 4,368,547 (-)NCBIHuRef
CHM1_1164,390,188 - 4,401,147 (-)NCBICHM1_1
T2T-CHM13v2.0164,367,543 - 4,380,493 (-)NCBIT2T-CHM13v2.0
Pam16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,434,330 - 4,442,810 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,434,328 - 4,442,852 (-)EnsemblGRCm39 Ensembl
GRCm38164,616,466 - 4,624,946 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,616,464 - 4,624,988 (-)EnsemblGRCm38mm10GRCm38
MGSCv37164,616,466 - 4,624,946 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,531,694 - 4,540,174 (-)NCBIMGSCv36mm8
Celera165,245,931 - 5,254,413 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.45NCBI
Pam16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,449,316 - 11,457,071 (+)NCBIGRCr8
mRatBN7.21010,942,534 - 10,950,654 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1010,943,001 - 10,950,649 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,651,764 - 15,659,342 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01015,140,582 - 15,148,160 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,809,734 - 10,817,306 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01011,146,359 - 11,153,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1011,146,359 - 11,153,936 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,911,717 - 9,919,294 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41011,072,402 - 11,079,980 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera109,905,330 - 9,912,908 (+)NCBICelera
Cytogenetic Map10q12NCBI
Pam16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544213,087,092 - 13,097,048 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544213,087,082 - 13,097,048 (+)NCBIChiLan1.0ChiLan1.0
PAM16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1637,040,484 - 37,047,708 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,368,787 - 38,376,010 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0637,244,809 - 37,252,032 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl637,184,569 - 37,252,759 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1637,039,040 - 37,046,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,932,206 - 36,939,429 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0637,333,506 - 37,340,730 (+)NCBIUU_Cfam_GSD_1.0
Pam16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,547,828 - 106,555,515 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936694153,959 - 161,635 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936694153,958 - 161,635 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100513346
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,928,096 - 37,985,151 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,928,098 - 38,005,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,983,207 - 39,040,262 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAM16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,020,116 - 4,031,233 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606826,660,330 - 26,671,448 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pam16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474618,235,774 - 18,237,603 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000050680   ⟹   ENSPPAP00000027837
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,418,006 - 4,445,625 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050685   ⟹   ENSPPAP00000027842
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,421,899 - 4,445,761 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050729   ⟹   ENSPPAP00000027886
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,426,355 - 4,510,963 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050733   ⟹   ENSPPAP00000027890
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,426,355 - 4,430,377 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050734   ⟹   ENSPPAP00000027891
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,426,355 - 4,429,825 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050737   ⟹   ENSPPAP00000027894
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,426,355 - 4,429,740 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050746   ⟹   ENSPPAP00000027903
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,448,849 - 4,515,038 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050760   ⟹   ENSPPAP00000027917
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,449,417 - 4,510,963 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050766   ⟹   ENSPPAP00000027923
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,449,463 - 4,510,963 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000050782   ⟹   ENSPPAP00000027939
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl164,452,123 - 4,459,098 (-)Ensembl
RefSeq Acc Id: XM_057299976   ⟹   XP_057155959
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2184,850,848 - 4,863,793 (-)NCBI
NHGRI_mPanPan1168,635,441 - 8,672,556 (-)NCBI
RefSeq Acc Id: XM_057299977   ⟹   XP_057155960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2184,851,080 - 4,883,025 (-)NCBI
NHGRI_mPanPan1168,637,348 - 8,672,712 (-)NCBI
RefSeq Acc Id: XM_057299978   ⟹   XP_057155961
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2184,863,056 - 4,883,023 (-)NCBI
NHGRI_mPanPan1168,647,470 - 8,672,710 (-)NCBI
RefSeq Acc Id: XR_008954889
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2184,847,319 - 4,863,793 (-)NCBI
NHGRI_mPanPan1168,631,732 - 8,675,724 (-)NCBI
RefSeq Acc Id: XP_057155959   ⟸   XM_057299976
- Peptide Label: isoform X1
RefSeq Acc Id: XP_057155960   ⟸   XM_057299977
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BHT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155961   ⟸   XM_057299978
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BHT9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000027923   ⟸   ENSPPAT00000050766
Ensembl Acc Id: ENSPPAP00000027842   ⟸   ENSPPAT00000050685
Ensembl Acc Id: ENSPPAP00000027890   ⟸   ENSPPAT00000050733
Ensembl Acc Id: ENSPPAP00000027837   ⟸   ENSPPAT00000050680
Ensembl Acc Id: ENSPPAP00000027939   ⟸   ENSPPAT00000050782
Ensembl Acc Id: ENSPPAP00000027903   ⟸   ENSPPAT00000050746
Ensembl Acc Id: ENSPPAP00000027891   ⟸   ENSPPAT00000050734
Ensembl Acc Id: ENSPPAP00000027917   ⟸   ENSPPAT00000050760
Ensembl Acc Id: ENSPPAP00000027886   ⟸   ENSPPAT00000050729
Ensembl Acc Id: ENSPPAP00000027894   ⟸   ENSPPAT00000050737
Protein Domains
DUF1899


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036983 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050680.1 UniProtKB/TrEMBL
  ENSPPAT00000050729.1 UniProtKB/TrEMBL
  ENSPPAT00000050733.1 UniProtKB/TrEMBL
  ENSPPAT00000050734.1 UniProtKB/TrEMBL
  ENSPPAT00000050737.1 UniProtKB/TrEMBL
  ENSPPAT00000050782.1 UniProtKB/TrEMBL
Gene3D-CATH DnaJ domain UniProtKB/TrEMBL
  YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/TrEMBL
InterPro Coronin UniProtKB/TrEMBL
  DUF1899 UniProtKB/TrEMBL
  J_dom_sf UniProtKB/TrEMBL
  Quinoprotein_ADH-like_supfam UniProtKB/TrEMBL
  Tim16 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_rpt UniProtKB/TrEMBL
NCBI Gene LOC117976183 ENTREZGENE
PANTHER CORONIN UniProtKB/TrEMBL
  CORONIN-7 UniProtKB/TrEMBL
  MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE UniProtKB/TrEMBL
  MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 UniProtKB/TrEMBL
Pfam DUF1899 UniProtKB/TrEMBL
  Pam16 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
  WD40_4 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART DUF1899 UniProtKB/TrEMBL
  DUF1900 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP Putative isomerase YbhE UniProtKB/TrEMBL
  Quinoprotein alcohol dehydrogenase-like UniProtKB/TrEMBL
UniProt A0A2R9BE33_PANPA UniProtKB/TrEMBL
  A0A2R9BE35_PANPA UniProtKB/TrEMBL
  A0A2R9BE72_PANPA UniProtKB/TrEMBL
  A0A2R9BHT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BHT9 ENTREZGENE
  A0A2R9BMJ1_PANPA UniProtKB/TrEMBL
  A0A2R9BMJ5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-21 PAM16  presequence translocase associated motor 16  LOC117976183  nascent polypeptide-associated complex subunit alpha, muscle-specific form-like  Symbol and/or name change 5135510 APPROVED