FAM229B (family with sequence similarity 229 member B) - Rat Genome Database

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Gene: FAM229B (family with sequence similarity 229 member B) Homo sapiens
Analyze
Symbol: FAM229B
Name: family with sequence similarity 229 member B
RGD ID: 2298836
HGNC Page HGNC:33858
Description: INTERACTS WITH aflatoxin B1; all-trans-retinoic acid; benzo[a]pyrene
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C6orf225; DKFZp586F0922; family with sequence similarity 229, member B; hypothetical protein LOC619208; UPF0731 protein C6orf225
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386112,087,591 - 112,102,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6112,087,591 - 112,102,790 (+)EnsemblGRCh38hg38GRCh38
GRCh376112,408,794 - 112,423,993 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366112,515,367 - 112,530,686 (+)NCBINCBI36Build 36hg18NCBI36
Celera6113,149,981 - 113,165,299 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6109,983,541 - 109,998,854 (+)NCBIHuRef
CHM1_16112,671,010 - 112,686,329 (+)NCBICHM1_1
T2T-CHM13v2.06113,271,009 - 113,286,208 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:32296183   PMID:32707033  


Genomics

Comparative Map Data
FAM229B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386112,087,591 - 112,102,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6112,087,591 - 112,102,790 (+)EnsemblGRCh38hg38GRCh38
GRCh376112,408,794 - 112,423,993 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366112,515,367 - 112,530,686 (+)NCBINCBI36Build 36hg18NCBI36
Celera6113,149,981 - 113,165,299 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6109,983,541 - 109,998,854 (+)NCBIHuRef
CHM1_16112,671,010 - 112,686,329 (+)NCBICHM1_1
T2T-CHM13v2.06113,271,009 - 113,286,208 (+)NCBIT2T-CHM13v2.0
Fam229b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391038,994,800 - 39,009,936 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1038,994,800 - 39,009,910 (-)EnsemblGRCm39 Ensembl
GRCm381039,118,804 - 39,133,914 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1039,118,804 - 39,133,914 (-)EnsemblGRCm38mm10GRCm38
MGSCv371038,838,614 - 38,853,701 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361038,808,224 - 38,823,311 (-)NCBIMGSCv36mm8
Celera1040,003,019 - 40,018,124 (-)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1020.14NCBI
Fam229b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82044,093,492 - 44,106,871 (-)NCBIGRCr8
mRatBN7.22042,538,853 - 42,552,355 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2042,538,868 - 42,552,248 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2044,287,635 - 44,301,174 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02043,946,840 - 43,960,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02044,677,464 - 44,690,973 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02044,207,463 - 44,220,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2044,207,478 - 44,220,702 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02045,931,971 - 45,947,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42043,266,782 - 43,279,959 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2043,255,097 - 43,268,621 (-)NCBICelera
Cytogenetic Map20q12NCBI
Fam229b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555264,469,766 - 4,484,738 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555264,469,766 - 4,484,934 (-)NCBIChiLan1.0ChiLan1.0
FAM229B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25132,103,553 - 132,117,927 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16129,991,763 - 130,006,138 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06109,897,954 - 109,914,304 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16113,973,172 - 113,989,558 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6113,973,172 - 113,989,558 (+)Ensemblpanpan1.1panPan2
FAM229B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11268,514,195 - 68,527,031 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1268,514,303 - 68,527,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1268,333,036 - 68,353,188 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01269,396,303 - 69,416,542 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1269,396,419 - 69,409,236 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11268,755,779 - 68,776,092 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01268,593,289 - 68,613,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01268,920,274 - 68,940,474 (+)NCBIUU_Cfam_GSD_1.0
Fam229b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946103,551,167 - 103,566,092 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936679783,329 - 802,838 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936679783,363 - 798,261 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM229B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl178,058,529 - 78,063,272 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1178,048,496 - 78,063,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,717,419 - 87,732,096 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAM229B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11361,755,601 - 61,769,048 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1361,755,707 - 61,768,921 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604034,091,212 - 34,104,801 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in FAM229B
8 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q21-23.2(chr6:108944899-132067720)x1 copy number loss See cases [RCV000051196] Chr6:108944899..132067720 [GRCh38]
Chr6:109266102..132388860 [GRCh37]
Chr6:109372795..132430553 [NCBI36]
Chr6:6q21-23.2		 pathogenic
GRCh38/hg38 6q21(chr6:111948842-112906602)x3 copy number gain See cases [RCV000134931] Chr6:111948842..112906602 [GRCh38]
Chr6:112270045..113227804 [GRCh37]
Chr6:112376738..113334497 [NCBI36]
Chr6:6q21		 uncertain significance
GRCh38/hg38 6q21-22.1(chr6:107370141-115827482)x1 copy number loss See cases [RCV000138006] Chr6:107370141..115827482 [GRCh38]
Chr6:107691345..116148646 [GRCh37]
Chr6:107798038..116255339 [NCBI36]
Chr6:6q21-22.1		 pathogenic
GRCh38/hg38 6q16.1-22.31(chr6:96609994-122161548)x1 copy number loss See cases [RCV000139465] Chr6:96609994..122161548 [GRCh38]
Chr6:97057870..122482694 [GRCh37]
Chr6:97164591..122524393 [NCBI36]
Chr6:6q16.1-22.31		 pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1		 pathogenic
GRCh38/hg38 6q21-22.31(chr6:106503719-125781219)x1 copy number loss See cases [RCV000141587] Chr6:106503719..125781219 [GRCh38]
Chr6:106951594..126102365 [GRCh37]
Chr6:107058287..126144058 [NCBI36]
Chr6:6q21-22.31		 pathogenic
GRCh38/hg38 6q21(chr6:112010915-112244218)x1 copy number loss See cases [RCV000141793] Chr6:112010915..112244218 [GRCh38]
Chr6:112332118..112565420 [GRCh37]
Chr6:112438811..112672113 [NCBI36]
Chr6:6q21		 uncertain significance
GRCh38/hg38 6q16.3-21(chr6:103279465-113934239)x1 copy number loss See cases [RCV000142287] Chr6:103279465..113934239 [GRCh38]
Chr6:103727340..114255403 [GRCh37]
Chr6:103834033..114362096 [NCBI36]
Chr6:6q16.3-21		 pathogenic
GRCh38/hg38 6q16.3-22.31(chr6:100054889-120488154)x1 copy number loss See cases [RCV000143227] Chr6:100054889..120488154 [GRCh38]
Chr6:100502765..120809300 [GRCh37]
Chr6:100609486..120850999 [NCBI36]
Chr6:6q16.3-22.31		 pathogenic
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687)x1 copy number loss See cases [RCV000445666] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31		 pathogenic
GRCh37/hg19 6q21-q22(chr6:112069445-120994664)x1 copy number loss 6q21-6q22.1 deletion [RCV000416567] Chr6:112069445..120994664 [GRCh37]
Chr6:6q21-22.31		 likely pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_001033564.3(FAM229B):c.77G>C (p.Gly26Ala) single nucleotide variant not specified [RCV004324308] Chr6:112099360 [GRCh38]
Chr6:112420563 [GRCh37]
Chr6:6q21		 uncertain significance
NM_001033564.3(FAM229B):c.171T>A (p.Asp57Glu) single nucleotide variant not specified [RCV004311579] Chr6:112100715 [GRCh38]
Chr6:112421918 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6q16.1-22.1(chr6:95549951-116684929)x1 copy number loss not provided [RCV000682693] Chr6:95549951..116684929 [GRCh37]
Chr6:6q16.1-22.1		 pathogenic
GRCh37/hg19 6q21(chr6:112249382-113216278)x3 copy number gain not provided [RCV000682710] Chr6:112249382..113216278 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_001033564.3(FAM229B):c.233A>G (p.His78Arg) single nucleotide variant not specified [RCV004311694] Chr6:112100777 [GRCh38]
Chr6:112421980 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6q21-22.31(chr6:110981075-119608396)x1 copy number loss not provided [RCV000848701] Chr6:110981075..119608396 [GRCh37]
Chr6:6q21-22.31		 pathogenic
GRCh37/hg19 6q21(chr6:112421899-112461960)x1 copy number loss not provided [RCV000849802] Chr6:112421899..112461960 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6q21(chr6:112352198-112457238)x3 copy number gain not provided [RCV000847368] Chr6:112352198..112457238 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6q16.3-22.1(chr6:101296547-117004249)x3 copy number gain Microcephaly [RCV001251053] Chr6:101296547..117004249 [GRCh37]
Chr6:6q16.3-22.1		 pathogenic
GRCh37/hg19 6q16.1-21(chr6:98949950-114533905)x1 copy number loss Deletion 6q16 q21 [RCV001263224] Chr6:98949950..114533905 [GRCh37]
Chr6:6q16.1-21		 pathogenic
GRCh37/hg19 6q21(chr6:109796301-113083437)x3 copy number gain See cases [RCV001353182] Chr6:109796301..113083437 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687) copy number loss not specified [RCV002053595] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31		 pathogenic
GRCh37/hg19 6q21-22.1(chr6:110472732-114762836) copy number loss not specified [RCV002053609] Chr6:110472732..114762836 [GRCh37]
Chr6:6q21-22.1		 uncertain significance
GRCh37/hg19 6q15-22.2(chr6:92054891-118329651) copy number loss not specified [RCV002053598] Chr6:92054891..118329651 [GRCh37]
Chr6:6q15-22.2		 pathogenic
NM_001033564.3(FAM229B):c.231G>A (p.Met77Ile) single nucleotide variant not specified [RCV004158138] Chr6:112100775 [GRCh38]
Chr6:112421978 [GRCh37]
Chr6:6q21		 uncertain significance
NM_001033564.3(FAM229B):c.90T>G (p.Ser30Arg) single nucleotide variant not specified [RCV004175707] Chr6:112099373 [GRCh38]
Chr6:112420576 [GRCh37]
Chr6:6q21		 uncertain significance
NM_001033564.3(FAM229B):c.197C>T (p.Thr66Met) single nucleotide variant not specified [RCV004256546] Chr6:112100741 [GRCh38]
Chr6:112421944 [GRCh37]
Chr6:6q21		 likely benign
GRCh37/hg19 6q21-23.2(chr6:110546061-131896074)x3 copy number gain not specified [RCV003986625] Chr6:110546061..131896074 [GRCh37]
Chr6:6q21-23.2		 likely pathogenic
GRCh37/hg19 6q21(chr6:112107860-113572662)x1 copy number loss not specified [RCV003986615] Chr6:112107860..113572662 [GRCh37]
Chr6:6q21		 uncertain significance
NM_001033564.3(FAM229B):c.182C>G (p.Thr61Ser) single nucleotide variant not specified [RCV004381299] Chr6:112100726 [GRCh38]
Chr6:112421929 [GRCh37]
Chr6:6q21		 uncertain significance
GRCh37/hg19 6q21-22.31(chr6:109324789-124836619)x1 copy number loss not provided [RCV004577478] Chr6:109324789..124836619 [GRCh37]
Chr6:6q21-22.31		 pathogenic
NM_001033564.3(FAM229B):c.172G>A (p.Val58Ile) single nucleotide variant not specified [RCV004381298] Chr6:112100716 [GRCh38]
Chr6:112421919 [GRCh37]
Chr6:6q21		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:722
Count of miRNA genes:551
Interacting mature miRNAs:600
Transcripts:ENST00000368656, ENST00000604268
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH102944  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,407,853 - 112,408,031UniSTSGRCh37
Build 366112,514,546 - 112,514,724RGDNCBI36
Celera6113,149,160 - 113,149,338RGD
Cytogenetic Map6q21UniSTS
HuRef6109,982,720 - 109,982,898UniSTS
GeneMap99-GB4 RH Map6478.13UniSTS
SHGC-84449  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,407,750 - 112,408,040UniSTSGRCh37
Build 366112,514,443 - 112,514,733RGDNCBI36
Celera6113,149,057 - 113,149,347RGD
Cytogenetic Map6q21UniSTS
HuRef6109,982,617 - 109,982,907UniSTS
TNG Radiation Hybrid Map653326.0UniSTS
D6S1259  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,419,366 - 112,419,465UniSTSGRCh37
Build 366112,526,059 - 112,526,158RGDNCBI36
Celera6113,160,672 - 113,160,771RGD
Cytogenetic Map6q21UniSTS
HuRef6109,994,227 - 109,994,326UniSTS
Whitehead-RH Map6691.2UniSTS
Whitehead-YAC Contig Map6 UniSTS
NCBI RH Map61429.4UniSTS
D8S2279  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.12UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map17q24.2UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map12q24.1UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map2p25.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q14UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map9q34.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map6p21.1-p12UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map8p23UniSTS
Cytogenetic Map11q13.2-q13.3UniSTS
Cytogenetic Map13q14.1-q14.3UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map3q13.1-q13.2UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7q32UniSTS
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Cytogenetic Map10p12.31UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map5q33.2UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map8q21.2UniSTS
Cytogenetic Map2q24.1UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map2q23.3UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map14q31UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map8p12-p11UniSTS
Cytogenetic Map18p11.2UniSTS
Cytogenetic Map7p11.1UniSTS
Cytogenetic Map1q31-q32UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map3p21.32UniSTS
Cytogenetic Map2p24.2UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map6q24.1UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map10q26.11UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic Map7p13-p12UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map17q11-q21UniSTS
Cytogenetic Map12q23UniSTS
Cytogenetic Map6p24-p22.3UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map7q31.1-q31.2UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map3p26.1-p25.1UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map4p15.2UniSTS
Cytogenetic Map6q16.3UniSTS
Cytogenetic Map17q24-q25UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic MapXq27.1UniSTS
Cytogenetic Map8q12.3UniSTS
Cytogenetic Map5q21.2UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map4q35.2UniSTS
Cytogenetic Map3p26.1UniSTS
Cytogenetic Map3p11.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map2q21.2UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map18q12.3UniSTS
Cytogenetic Map18p11.3UniSTS
Cytogenetic Map17q11.1UniSTS
Cytogenetic Map15q25.1UniSTS
Cytogenetic Map13q12.3UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map12q12-q13UniSTS
Cytogenetic Map12q14UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map2q32-q34UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic Map2p15-p13UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map19q13.33-q13.41UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map6q23-q24UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic Map13q11-q12UniSTS
Cytogenetic Map6p12.3-p11.2UniSTS
Cytogenetic Map6q16.1-q16.3UniSTS
Cytogenetic Map22q11UniSTS
Cytogenetic Map7q31.2UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map3q25.2UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map3q23-q24UniSTS
Cytogenetic Map3q12UniSTS
Cytogenetic Map7q11.1UniSTS
Cytogenetic Map3q22.3UniSTS
Cytogenetic Map7q21.3UniSTS
Cytogenetic Map4q31.1UniSTS
Cytogenetic Map22q12-q13UniSTS
Cytogenetic Map4q23UniSTS
Cytogenetic MapXp22.12UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map18q21.3UniSTS
Cytogenetic Map9q33.2UniSTS
Cytogenetic Map11q21UniSTS
Cytogenetic Map8q12UniSTS
Cytogenetic Map4q28-q32UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map6p23UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map1q24.3UniSTS
Cytogenetic Map9q33.1UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map2p16.2UniSTS
Cytogenetic Map9q22.31UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map16p12UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map13q22.1UniSTS
Cytogenetic Map2q12.2UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map4q21UniSTS
Cytogenetic Map13q12.2UniSTS
Cytogenetic Map9q31-q33UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map1q23UniSTS
Cytogenetic Map11q12-q13UniSTS
Cytogenetic Map11q13.3UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map11q12.1UniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map8p21UniSTS
Cytogenetic Map19q13.1-q13.2UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map7q36.2UniSTS
Cytogenetic Map4q32.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map9q32-q33.3UniSTS
Cytogenetic Map9q22.1-q22.2UniSTS
Cytogenetic Map3q26.1-q26.2UniSTS
Cytogenetic Map5q31-q34UniSTS
Cytogenetic Map9q33-q34UniSTS
Cytogenetic Map5q11.2-q13.2UniSTS
Cytogenetic Map13q32UniSTS
Cytogenetic Map9q22.32UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map4q28.1UniSTS
Cytogenetic Map5q22UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic MapXq13.3UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map3p26.3UniSTS
Cytogenetic Map2q11.1UniSTS
Cytogenetic Map21q11.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map12q24.23UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map2q31.1-q31.2UniSTS
Cytogenetic MapXp22.31UniSTS
Cytogenetic MapXp21.3UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map4q28.2UniSTS
Cytogenetic Map3p14.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map20q13.2UniSTS
Cytogenetic Map14q11.2-q12UniSTS
Cytogenetic Map3p24UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map11q24.3UniSTS
Cytogenetic Map11q14.3UniSTS
Cytogenetic Map10q25.2UniSTS
Cytogenetic Map3q25.1UniSTS
Cytogenetic Map8q13UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map3p22.3UniSTS
Cytogenetic Map18q11.1UniSTS
Cytogenetic Map8q23.3UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic Map11cen-q12UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map12q21UniSTS
Cytogenetic Map7p15UniSTS
Cytogenetic Map7q22-q31UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map5p15.3UniSTS
Cytogenetic Map20q13.3-qterUniSTS
Cytogenetic Map1p35-p34UniSTS
Cytogenetic Map4p13-p12UniSTS
Cytogenetic Map10q21-q22UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map7p13-p11.1UniSTS
Cytogenetic Map9q31-q34UniSTS
Cytogenetic Map7q21.1-q22UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map3q13.13-q13.2UniSTS
Cytogenetic MapXp22.13UniSTS
Cytogenetic Map13q12.12UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1pUniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map15qUniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map2qUniSTS
Cytogenetic Map5q13.1UniSTS
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map2p22UniSTS
Cytogenetic Map5q14.3UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map5q23.2UniSTS
Cytogenetic Map2p24.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map12p13.32UniSTS
Cytogenetic Map9p21.1UniSTS
Cytogenetic Map9q34.2-q34.3UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2437 2788 2253 4974 1726 2351 6 624 1935 465 2270 7289 6456 53 3734 1 852 1744 1617 174 1

Sequence


Ensembl Acc Id: ENST00000368656   ⟹   ENSP00000357645
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6112,087,591 - 112,102,790 (+)Ensembl
Ensembl Acc Id: ENST00000604268   ⟹   ENSP00000474987
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6112,087,638 - 112,100,895 (+)Ensembl
RefSeq Acc Id: NM_001033564   ⟹   NP_001028736
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386112,087,591 - 112,102,790 (+)NCBI
GRCh376112,408,674 - 112,423,993 (+)RGD
Build 366112,515,367 - 112,530,686 (+)NCBI Archive
Celera6113,149,981 - 113,165,299 (+)RGD
HuRef6109,983,541 - 109,998,854 (+)ENTREZGENE
CHM1_16112,671,010 - 112,686,329 (+)NCBI
T2T-CHM13v2.06113,271,009 - 113,286,208 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017011174   ⟹   XP_016866663
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386112,087,591 - 112,102,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017011175   ⟹   XP_016866664
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386112,087,591 - 112,102,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054356186   ⟹   XP_054212161
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.06113,271,009 - 113,286,208 (+)NCBI
RefSeq Acc Id: XM_054356187   ⟹   XP_054212162
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.06113,271,009 - 113,286,208 (+)NCBI
RefSeq Acc Id: NP_001028736   ⟸   NM_001033564
- UniProtKB: B8ZZ33 (UniProtKB/Swiss-Prot),   Q4G0N7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866664   ⟸   XM_017011175
- Peptide Label: isoform X1
- UniProtKB: B8ZZ33 (UniProtKB/Swiss-Prot),   Q4G0N7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866663   ⟸   XM_017011174
- Peptide Label: isoform X1
- UniProtKB: B8ZZ33 (UniProtKB/Swiss-Prot),   Q4G0N7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000357645   ⟸   ENST00000368656
Ensembl Acc Id: ENSP00000474987   ⟸   ENST00000604268
RefSeq Acc Id: XP_054212161   ⟸   XM_054356186
- Peptide Label: isoform X1
- UniProtKB: Q4G0N7 (UniProtKB/Swiss-Prot),   B8ZZ33 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054212162   ⟸   XM_054356187
- Peptide Label: isoform X1
- UniProtKB: Q4G0N7 (UniProtKB/Swiss-Prot),   B8ZZ33 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4G0N7-F1-model_v2 AlphaFold Q4G0N7 1-80 view protein structure

Promoters
RGD ID:7208925
Promoter ID:EPDNEW_H10208
Type:initiation region
Name:FAM229B_1
Description:family with sequence similarity 229 member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386112,087,634 - 112,087,694EPDNEW
RGD ID:6803853
Promoter ID:HG_KWN:54698
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   CD4+TCell_2Hour,   K562,   Lymphoblastoid
Transcripts:NM_001033564
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,515,131 - 112,515,631 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33858 AgrOrtholog
COSMIC FAM229B COSMIC
Ensembl Genes ENSG00000203778 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000368656 ENTREZGENE
  ENST00000368656.7 UniProtKB/Swiss-Prot
  ENST00000604268.1 UniProtKB/Swiss-Prot
GTEx ENSG00000203778 GTEx
HGNC ID HGNC:33858 ENTREZGENE
Human Proteome Map FAM229B Human Proteome Map
InterPro FAM229 UniProtKB/Swiss-Prot
KEGG Report hsa:619208 UniProtKB/Swiss-Prot
NCBI Gene 619208 ENTREZGENE
PANTHER PROTEIN FAM229B UniProtKB/Swiss-Prot
  PTHR35355 UniProtKB/Swiss-Prot
Pfam UPF0731 UniProtKB/Swiss-Prot
PharmGKB PA162380460 PharmGKB
UniProt B8ZZ33 ENTREZGENE
  F229B_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B8ZZ33 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 FAM229B  family with sequence similarity 229 member B    family with sequence similarity 229, member B  Symbol and/or name change 5135510 APPROVED
2012-12-18 FAM229B  family with sequence similarity 229, member B  C6orf225  chromosome 6 open reading frame 225  Symbol and/or name change 5135510 APPROVED