Scarb2 (scavenger receptor class B member 2) - Rat Genome Database

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Gene: Scarb2 (scavenger receptor class B member 2) Heterocephalus glaber
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Symbol: Scarb2
Name: scavenger receptor class B member 2
RGD ID: 18936948
Description: ENCODES a protein that exhibits cargo receptor activity (ortholog); cholesterol binding (ortholog); enzyme binding (ortholog); INVOLVED IN aminophospholipid transport (ortholog); endosome to plasma membrane protein transport (ortholog); positive regulation of neuron projection development (ortholog); ASSOCIATED WITH benign epilepsy with centrotemporal spikes (ortholog); COVID-19 (ortholog); epilepsy (ortholog); FOUND IN endocytic vesicle membrane (ortholog); lysosomal lumen (ortholog); lysosomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Lysosome membrane protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475714,709,120 - 14,795,243 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475714,709,120 - 14,795,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Scarb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475714,709,120 - 14,795,243 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475714,709,120 - 14,795,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SCARB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38476,158,737 - 76,234,532 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl476,158,737 - 76,234,536 (-)EnsemblGRCh38hg38GRCh38
GRCh37477,079,890 - 77,134,977 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36477,298,918 - 77,354,059 (-)NCBINCBI36Build 36hg18NCBI36
Build 34477,437,072 - 77,492,214NCBI
Celera474,380,030 - 74,435,161 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef472,831,916 - 72,887,070 (-)NCBIHuRef
CHM1_1477,056,276 - 77,111,407 (-)NCBICHM1_1
T2T-CHM13v2.0479,499,409 - 79,554,492 (-)NCBIT2T-CHM13v2.0
Scarb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,589,170 - 92,653,516 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl592,589,173 - 92,654,692 (-)EnsemblGRCm39 Ensembl
GRCm38592,441,311 - 92,505,657 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,441,314 - 92,506,833 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,872,899 - 92,934,634 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36593,519,073 - 93,580,808 (-)NCBIMGSCv36mm8
Celera590,592,338 - 90,656,687 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map546.82NCBI
Scarb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81415,842,583 - 15,894,123 (+)NCBIGRCr8
mRatBN7.21415,558,271 - 15,609,813 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,558,236 - 15,609,813 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1415,566,223 - 15,618,045 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01416,885,066 - 16,936,897 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,580,484 - 15,632,314 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01417,064,173 - 17,115,620 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,064,353 - 17,115,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01416,980,270 - 17,031,712 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41417,119,366 - 17,170,850 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11417,119,365 - 17,170,850 (+)NCBI
Celera1414,952,893 - 15,004,293 (+)NCBICelera
Cytogenetic Map14p22NCBI
Scarb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955433884,740 - 962,932 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955433884,740 - 962,932 (-)NCBIChiLan1.0ChiLan1.0
SCARB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2353,859,642 - 53,914,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1454,049,355 - 54,104,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0447,992,589 - 48,047,528 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1453,830,488 - 53,886,065 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl453,830,488 - 53,886,059 (+)Ensemblpanpan1.1panPan2
SCARB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.132788,117 - 865,496 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl32790,379 - 865,502 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3241,016,853 - 41,094,397 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.032814,945 - 891,722 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl32814,948 - 891,728 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.132812,765 - 889,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.032767,039 - 843,700 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03239,325,616 - 39,402,476 (+)NCBIUU_Cfam_GSD_1.0
Scarb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528511,281,403 - 11,339,761 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936676170,010 - 225,457 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936676167,482 - 225,827 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCARB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl871,838,397 - 71,940,607 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1871,838,395 - 71,910,461 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2876,034,114 - 76,105,880 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCARB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1724,658,734 - 24,714,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl724,658,211 - 24,714,597 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660373,007,021 - 3,062,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024672   ⟹   ENSHGLP00000024451
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475714,709,120 - 14,795,243 (+)Ensembl
RefSeq Acc Id: XM_004848034   ⟹   XP_004848091
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475714,709,120 - 14,795,039 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004848091 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09521 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024451
GenBank Protein JAO01969 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004848091   ⟸   XM_004848034
- UniProtKB: A0A0P6JEM8 (UniProtKB/TrEMBL),   G5BJR0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000024451   ⟸   ENSHGLT00000024672


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017432 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024672 ENTREZGENE
InterPro CD36_fam UniProtKB/TrEMBL
  LimpII UniProtKB/TrEMBL
KEGG Report hgl:101715798 UniProtKB/TrEMBL
NCBI Gene Scarb2 ENTREZGENE
PANTHER LYSOSOME MEMBRANE PROTEIN 2 UniProtKB/TrEMBL
  PTHR11923 UniProtKB/TrEMBL
Pfam CD36 UniProtKB/TrEMBL
PRINTS CD36FAMILY UniProtKB/TrEMBL
  LIMPII UniProtKB/TrEMBL
UniProt A0A0P6JEM8 ENTREZGENE, UniProtKB/TrEMBL
  G5BJR0 ENTREZGENE, UniProtKB/TrEMBL