Scarb2 (scavenger receptor class B, member 2) - Rat Genome Database

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Gene: Scarb2 (scavenger receptor class B, member 2) Mus musculus
Analyze
Symbol: Scarb2
Name: scavenger receptor class B, member 2
RGD ID: 732466
MGI Page MGI
Description: Enables several functions, including cholesterol binding activity; phospholipid binding activity; and protein homodimerization activity. Involved in several processes, including aminophospholipid transport; protein targeting to lysosome; and regulation of glucosylceramidase activity. Acts upstream of or within endosome to plasma membrane protein transport and sensory perception of sound. Located in endocytic vesicle membrane; lysosome; and plasma membrane. Is expressed in several structures, including brain; genitourinary system; liver; and retina. Used to study progressive myoclonus epilepsy. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 4. Orthologous to human SCARB2 (scavenger receptor class B member 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 85 kDa lysosomal membrane sialoglycoprotein; 9330185J12Rik; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; Cd36l; Cd36l2; LGP; LGP85; LIM; LIMP II; LIMP-2; lysosome membrane protein 2; lysosome membrane protein II; MLGP85; scavenger receptor class B member 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,589,170 - 92,653,516 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl592,589,173 - 92,654,692 (-)EnsemblGRCm39 Ensembl
GRCm38592,441,311 - 92,505,657 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,441,314 - 92,506,833 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,872,899 - 92,934,634 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36593,519,073 - 93,580,808 (-)NCBIMGSCv36mm8
Celera590,592,338 - 90,656,687 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map546.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
corosolic acid  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichlorvos  (ISO)
diethylstilbestrol  (EXP)
Enterolactone  (ISO)
ethanol  (EXP)
fenthion  (EXP)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
genistein  (EXP,ISO)
gentamycin  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
LY294002  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
metronidazole  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
nefazodone  (ISO)
neomycin  (ISO)
nimesulide  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
pirinixic acid  (EXP,ISO)
resveratrol  (ISO)
rotenone  (EXP)
sarin  (ISO)
SB 431542  (ISO)
sirolimus  (ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
tauroursodeoxycholic acid  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (EXP)
thioacetamide  (ISO)
topotecan  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
Yessotoxin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal auditory brainstem response  (IAGP)
abnormal behavior  (IAGP)
abnormal distortion product otoacoustic emission  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal otolithic membrane morphology  (IAGP)
abnormal phrenic nerve morphology  (IAGP)
abnormal QT variability  (IEA)
abnormal Schwann cell morphology  (IAGP)
abnormal sinus arrhythmia  (IEA)
abnormal stria vascularis morphology  (IAGP)
abnormal stria vascularis vasculature morphology  (IAGP)
abnormal strial marginal cell morphology  (IAGP)
abnormal ureter morphology  (IAGP)
abnormal ureter smooth muscle morphology  (IAGP)
abnormal ureteropelvic junction morphology  (IAGP)
abnormal urothelium morphology  (IAGP)
abnormal vestibular hair cell physiology  (IAGP)
absent endocochlear potential  (IAGP)
absent otoliths  (IAGP)
absent startle reflex  (IAGP)
albuminuria  (IAGP)
astrocytosis  (IAGP)
cardiovascular system phenotype  (IEA)
cochlear ganglion degeneration  (IAGP)
cochlear inner hair cell degeneration  (IAGP)
cochlear outer hair cell degeneration  (IAGP)
deafness  (IAGP)
decreased body weight  (IAGP)
decreased endocochlear potential  (IAGP)
decreased mean corpuscular volume  (IEA)
decreased monocyte cell number  (IEA)
decreased total body fat amount  (IEA)
decreased urine glucose level  (IAGP)
decreased urine osmolality  (IAGP)
demyelination  (IAGP)
dilated kidney calyx  (IAGP)
distended abdomen  (IAGP)
enlarged kidney  (IEA)
enlarged lymph nodes  (IEA)
hydronephrosis  (IAGP)
increased blood urea nitrogen level  (IEA)
increased bone mineral content  (IEA)
increased heart rate variability  (IEA)
increased lean body mass  (IEA)
increased leukocyte cell number  (IEA)
increased lymphocyte cell number  (IEA)
increased neutrophil cell number  (IEA)
leukocyturia  (IAGP)
limb grasping  (IAGP)
microgliosis  (IAGP)
neurodegeneration  (IAGP)
paralysis  (IAGP)
polydipsia  (IAGP)
polyuria  (IAGP)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
prolonged RR interval  (IEA)
sensorineural hearing loss  (IAGP)
stria vascularis degeneration  (IAGP)
thrombocytosis  (IEA)
tremors  (IAGP)
ureteropelvic junction obstruction  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9399579   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12055214   PMID:12055215   PMID:12356916   PMID:12376530   PMID:12477932   PMID:12520002  
PMID:12620969   PMID:12904583   PMID:14610273   PMID:15226823   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16901941   PMID:16919471   PMID:17071747   PMID:17485520  
PMID:17967808   PMID:18022370   PMID:18287559   PMID:18308289   PMID:18799693   PMID:19796621   PMID:19933215   PMID:21123180   PMID:21267068   PMID:21429972   PMID:21677750   PMID:21873635  
PMID:22219187   PMID:22496664   PMID:22988039   PMID:23344573   PMID:23635510   PMID:24212238   PMID:24394995   PMID:25027712   PMID:25316793   PMID:26219725   PMID:26724485   PMID:26907692  
PMID:27789271   PMID:28423002   PMID:29111364   PMID:29199275   PMID:30888112   PMID:31387993   PMID:34793693   PMID:35867561   PMID:35955761   PMID:36114006   PMID:37442135   PMID:37839992  
PMID:38355793  


Genomics

Comparative Map Data
Scarb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,589,170 - 92,653,516 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl592,589,173 - 92,654,692 (-)EnsemblGRCm39 Ensembl
GRCm38592,441,311 - 92,505,657 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,441,314 - 92,506,833 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,872,899 - 92,934,634 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36593,519,073 - 93,580,808 (-)NCBIMGSCv36mm8
Celera590,592,338 - 90,656,687 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map546.82NCBI
SCARB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38476,158,737 - 76,234,532 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl476,158,737 - 76,234,536 (-)EnsemblGRCh38hg38GRCh38
GRCh37477,079,890 - 77,134,977 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36477,298,918 - 77,354,059 (-)NCBINCBI36Build 36hg18NCBI36
Build 34477,437,072 - 77,492,214NCBI
Celera474,380,030 - 74,435,161 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef472,831,916 - 72,887,070 (-)NCBIHuRef
CHM1_1477,056,276 - 77,111,407 (-)NCBICHM1_1
T2T-CHM13v2.0479,499,409 - 79,554,492 (-)NCBIT2T-CHM13v2.0
Scarb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81415,842,583 - 15,894,123 (+)NCBIGRCr8
mRatBN7.21415,558,271 - 15,609,813 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,558,236 - 15,609,813 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1415,566,223 - 15,618,045 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01416,885,066 - 16,936,897 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,580,484 - 15,632,314 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01417,064,173 - 17,115,620 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,064,353 - 17,115,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01416,980,270 - 17,031,712 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41417,119,366 - 17,170,850 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11417,119,365 - 17,170,850 (+)NCBI
Celera1414,952,893 - 15,004,293 (+)NCBICelera
Cytogenetic Map14p22NCBI
Scarb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955433884,740 - 962,932 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955433884,740 - 962,932 (-)NCBIChiLan1.0ChiLan1.0
SCARB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2353,859,642 - 53,914,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1454,049,355 - 54,104,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0447,992,589 - 48,047,528 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1453,830,488 - 53,886,065 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl453,830,488 - 53,886,059 (+)Ensemblpanpan1.1panPan2
SCARB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.132788,117 - 865,496 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl32790,379 - 865,502 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3241,016,853 - 41,094,397 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.032814,945 - 891,722 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl32814,948 - 891,728 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.132812,765 - 889,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.032767,039 - 843,700 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03239,325,616 - 39,402,476 (+)NCBIUU_Cfam_GSD_1.0
Scarb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528511,281,403 - 11,339,761 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936676170,010 - 225,457 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936676167,482 - 225,827 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCARB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl871,838,397 - 71,940,607 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1871,838,395 - 71,910,461 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2876,034,114 - 76,105,880 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCARB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1724,658,734 - 24,714,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl724,658,211 - 24,714,597 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660373,007,021 - 3,062,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scarb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475714,709,120 - 14,795,243 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475714,709,120 - 14,795,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scarb2
3728 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:144
Interacting mature miRNAs:156
Transcripts:ENSMUST00000031377
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
12910784Pwgrq15_mpost-weaning growth rate QTL 15 (mouse)57717582397658215Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
12910816Ogrq2_moverall growth rate QTL 2 (mouse)57717582397658215Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
4141124Dshv2_mdorsal hippocampal volume 2 (mouse)Not determined57531534898019803Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB008553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB851354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE852231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD349164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV558446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000031377   ⟹   ENSMUSP00000031377
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl592,589,173 - 92,653,496 (-)Ensembl
GRCm38.p6 Ensembl592,441,314 - 92,505,637 (-)Ensembl
Ensembl Acc Id: ENSMUST00000201253
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl592,652,660 - 92,654,692 (-)Ensembl
GRCm38.p6 Ensembl592,504,801 - 92,506,833 (-)Ensembl
RefSeq Acc Id: NM_007644   ⟹   NP_031670
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39592,589,170 - 92,653,516 (-)NCBI
GRCm38592,441,311 - 92,505,657 (-)NCBI
MGSCv37592,872,899 - 92,934,634 (-)RGD
Celera590,592,338 - 90,656,687 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_031670   ⟸   NM_007644
- UniProtKB: O35114 (UniProtKB/Swiss-Prot),   Q3UNF8 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000031377   ⟸   ENSMUST00000031377

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35114-F1-model_v2 AlphaFold O35114 1-478 view protein structure

Promoters
RGD ID:6887184
Promoter ID:EPDNEW_M7043
Type:initiation region
Name:Scarb2_2
Description:Mus musculus scavenger receptor class B, member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7044  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38592,505,483 - 92,505,543EPDNEW
RGD ID:6887186
Promoter ID:EPDNEW_M7044
Type:initiation region
Name:Scarb2_1
Description:Mus musculus scavenger receptor class B, member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7043  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38592,505,646 - 92,505,706EPDNEW
RGD ID:6838290
Promoter ID:MM_KWN:42903
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_007644
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36592,934,421 - 92,934,972 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1196458 AgrOrtholog
Ensembl Genes ENSMUSG00000029426 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031377 ENTREZGENE
  ENSMUST00000031377.9 UniProtKB/Swiss-Prot
InterPro CD36_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LimpII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12492 UniProtKB/Swiss-Prot
MGD MGI:1196458 ENTREZGENE
NCBI Gene 12492 ENTREZGENE
PANTHER LYSOSOME MEMBRANE PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CD36 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scarb2 PhenoGen
PRINTS CD36FAMILY UniProtKB/Swiss-Prot
  LIMPII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt O35114 ENTREZGENE
  Q3TCS7_MOUSE UniProtKB/TrEMBL
  Q3UNF8 ENTREZGENE
  SCRB2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3UNF8 UniProtKB/Swiss-Prot