Trim33 (tripartite motif containing 33) - Rat Genome Database

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Gene: Trim33 (tripartite motif containing 33) Heterocephalus glaber
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Symbol: Trim33
Name: tripartite motif containing 33
RGD ID: 18936783
Description: ENCODES a protein that exhibits co-SMAD binding (ortholog); promoter-specific chromatin binding (ortholog); R-SMAD binding (ortholog); INVOLVED IN gene expression (ortholog); negative regulation of BMP signaling pathway (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH developmental dysplasia of the hip (ortholog); hereditary spastic paraplegia 47 (ortholog); ovarian cancer (ortholog); FOUND IN chromatin (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase TRIM33
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477210,030,640 - 10,140,607 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477210,026,951 - 10,140,529 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Trim33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477210,030,640 - 10,140,607 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477210,026,951 - 10,140,529 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TRIM33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381114,392,790 - 114,511,203 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1114,392,790 - 114,511,203 (-)EnsemblGRCh38hg38GRCh38
GRCh371114,935,412 - 115,053,824 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,736,922 - 114,855,304 (-)NCBINCBI36Build 36hg18NCBI36
Build 341114,652,284 - 114,765,823NCBI
Celera1113,164,629 - 113,283,011 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1112,793,962 - 112,912,354 (-)NCBIHuRef
CHM1_11115,050,539 - 115,168,646 (-)NCBICHM1_1
T2T-CHM13v2.01114,404,478 - 114,522,654 (-)NCBIT2T-CHM13v2.0
Trim33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393103,186,609 - 103,266,086 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3103,186,609 - 103,266,091 (+)EnsemblGRCm39 Ensembl
GRCm383103,279,293 - 103,358,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3103,279,293 - 103,358,775 (+)EnsemblGRCm38mm10GRCm38
MGSCv373103,083,216 - 103,162,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363103,408,354 - 103,484,622 (+)NCBIMGSCv36mm8
Celera3105,488,403 - 105,567,813 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
Trim33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82193,495,743 - 193,588,595 (+)NCBIGRCr8
mRatBN7.22190,812,329 - 190,892,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2190,807,243 - 190,888,814 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02205,783,252 - 205,863,426 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2205,783,252 - 205,858,433 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02225,212,623 - 225,292,926 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42198,525,829 - 198,603,543 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12198,488,640 - 198,564,652 (+)NCBI
Celera2183,285,485 - 183,365,585 (+)NCBICelera
Cytogenetic Map2q34NCBI
Trim33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543517,631,602 - 17,750,261 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543517,631,596 - 17,750,261 (-)NCBIChiLan1.0ChiLan1.0
TRIM33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21107,052,869 - 107,173,646 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11106,646,789 - 106,767,619 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0188,043,031 - 88,163,804 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11123,095,727 - 123,215,231 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1123,095,244 - 123,210,355 (+)Ensemblpanpan1.1panPan2
TRIM33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11752,117,085 - 52,230,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1752,118,476 - 52,230,530 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1751,767,972 - 51,880,982 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01752,993,051 - 53,106,214 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1752,994,736 - 53,106,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11752,002,778 - 52,115,804 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01752,070,390 - 52,183,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01752,643,538 - 52,756,887 (-)NCBIUU_Cfam_GSD_1.0
Trim33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505814,579,332 - 14,768,680 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366902,709,061 - 2,830,450 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366902,709,059 - 2,898,399 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4106,058,109 - 106,191,800 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14106,058,197 - 106,195,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRIM33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12019,154,902 - 19,274,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2019,154,933 - 19,274,779 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603821,913,010 - 22,033,644 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000021755   ⟹   ENSHGLP00000021546
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477210,030,640 - 10,140,607 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000021756   ⟹   ENSHGLP00000021547
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477210,031,275 - 10,140,607 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000021757   ⟹   ENSHGLP00000021548
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477210,031,275 - 10,140,607 (-)Ensembl
RefSeq Acc Id: XM_004853777   ⟹   XP_004853834
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477210,026,951 - 10,140,529 (-)NCBI
RefSeq Acc Id: XM_004853778   ⟹   XP_004853835
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477210,026,951 - 10,140,529 (-)NCBI
RefSeq Acc Id: XR_002397967
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477210,026,951 - 10,140,529 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004853834 (Get FASTA)   NCBI Sequence Viewer  
  XP_004853835 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021547
  ENSHGLP00000021548
RefSeq Acc Id: XP_004853835   ⟸   XM_004853778
- Peptide Label: isoform X2
- UniProtKB: G5ATE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853834   ⟸   XM_004853777
- Peptide Label: isoform X1
- UniProtKB: G5ATE4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000021548   ⟸   ENSHGLT00000021757
Ensembl Acc Id: ENSHGLP00000021547   ⟸   ENSHGLT00000021756
Ensembl Acc Id: ENSHGLP00000021546   ⟸   ENSHGLT00000021755


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015394 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021756 ENTREZGENE
  ENSHGLT00000021757 ENTREZGENE
Gene3D-CATH Bromodomain-like UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
  Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
InterPro Bbox_C UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Trim33 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM33 UniProtKB/TrEMBL
  TRANSCRIPTION INTERMEDIARY FACTOR UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
PROSITE BROMODOMAIN_2 UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART BBC UniProtKB/TrEMBL
  BBOX UniProtKB/TrEMBL
  BROMO UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  FYVE/PHD zinc finger UniProtKB/TrEMBL
UniProt A0AAX6PKH6_HETGA UniProtKB/TrEMBL
  A0AAX6PKP7_HETGA UniProtKB/TrEMBL
  G5ATE4 ENTREZGENE, UniProtKB/TrEMBL