Trim33 (tripartite motif containing 33) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Trim33 (tripartite motif containing 33) Ictidomys tridecemlineatus
Analyze
Symbol: Trim33
Name: tripartite motif containing 33
RGD ID: 12505369
Description: ENCODES a protein that exhibits promoter-specific chromatin binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia 47 (ortholog); ovarian cancer (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase TRIM33
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505814,579,332 - 14,768,680 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366902,709,061 - 2,830,450 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366902,709,059 - 2,898,399 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Trim33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505814,579,332 - 14,768,680 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366902,709,061 - 2,830,450 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366902,709,059 - 2,898,399 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381114,392,790 - 114,511,203 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1114,392,790 - 114,511,203 (-)EnsemblGRCh38hg38GRCh38
GRCh371114,935,412 - 115,053,824 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,736,922 - 114,855,304 (-)NCBINCBI36Build 36hg18NCBI36
Build 341114,652,284 - 114,765,823NCBI
Celera1113,164,629 - 113,283,011 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1112,793,962 - 112,912,354 (-)NCBIHuRef
CHM1_11115,050,539 - 115,168,646 (-)NCBICHM1_1
T2T-CHM13v2.01114,404,478 - 114,522,654 (-)NCBIT2T-CHM13v2.0
Trim33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393103,186,609 - 103,266,086 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3103,186,609 - 103,266,091 (+)EnsemblGRCm39 Ensembl
GRCm383103,279,293 - 103,358,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3103,279,293 - 103,358,775 (+)EnsemblGRCm38mm10GRCm38
MGSCv373103,083,216 - 103,162,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363103,408,354 - 103,484,622 (+)NCBIMGSCv36mm8
Celera3105,488,403 - 105,567,813 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
Trim33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82193,495,743 - 193,588,595 (+)NCBIGRCr8
mRatBN7.22190,812,329 - 190,892,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2190,807,243 - 190,888,814 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02205,783,252 - 205,863,426 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2205,783,252 - 205,858,433 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02225,212,623 - 225,292,926 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42198,525,829 - 198,603,543 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12198,488,640 - 198,564,652 (+)NCBI
Celera2183,285,485 - 183,365,585 (+)NCBICelera
Cytogenetic Map2q34NCBI
Trim33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543517,631,602 - 17,750,261 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543517,631,596 - 17,750,261 (-)NCBIChiLan1.0ChiLan1.0
TRIM33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21107,052,869 - 107,173,646 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11106,646,789 - 106,767,619 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0188,043,031 - 88,163,804 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11123,095,727 - 123,215,231 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1123,095,244 - 123,210,355 (+)Ensemblpanpan1.1panPan2
TRIM33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11752,117,085 - 52,230,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1752,118,476 - 52,230,530 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1751,767,972 - 51,880,982 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01752,993,051 - 53,106,214 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1752,994,736 - 53,106,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11752,002,778 - 52,115,804 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01752,070,390 - 52,183,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01752,643,538 - 52,756,887 (-)NCBIUU_Cfam_GSD_1.0
TRIM33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4106,058,109 - 106,191,800 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14106,058,197 - 106,195,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRIM33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12019,154,902 - 19,274,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2019,154,933 - 19,274,779 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603821,913,010 - 22,033,644 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477210,030,640 - 10,140,607 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477210,026,951 - 10,140,529 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013363938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000024088   ⟹   ENSSTOP00000017434
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366902,713,995 - 2,830,450 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000040328   ⟹   ENSSTOP00000025975
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366902,709,061 - 2,830,450 (-)Ensembl
RefSeq Acc Id: XM_013363938   ⟹   XP_013219392
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505814,579,332 - 14,768,680 (+)NCBI
SpeTri2.0NW_0049366902,709,059 - 2,898,399 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013219392 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017434.2
  ENSSTOP00000025975.1
GenBank Protein KAG3281225 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013219392   ⟸   XM_013363938
- UniProtKB: A0A287CXC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000025975   ⟸   ENSSTOT00000040328
RefSeq Acc Id: ENSSTOP00000017434   ⟸   ENSSTOT00000024088
Protein Domains
B box-type   Bromo   PHD-type   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021676 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024088.2 UniProtKB/TrEMBL
  ENSSTOT00000040328.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro Bbox_C UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Trim33 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM33 UniProtKB/TrEMBL
  TRANSCRIPTION INTERMEDIARY FACTOR UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PROSITE BROMODOMAIN_2 UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBC UniProtKB/TrEMBL
  BBOX UniProtKB/TrEMBL
  BROMO UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF47370 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A287CXC0 ENTREZGENE, UniProtKB/TrEMBL
  I3MZ88_ICTTR UniProtKB/TrEMBL