Tspan5 (tetraspanin 5) - Rat Genome Database

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Gene: Tspan5 (tetraspanin 5) Heterocephalus glaber
Analyze
Symbol: Tspan5
Name: tetraspanin 5
RGD ID: 18935336
Description: ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN positive regulation of Notch signaling pathway (ortholog); protein localization to plasma membrane (ortholog); protein maturation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN actin cytoskeleton (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tetraspanin-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475726,557,898 - 26,733,209 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475726,558,052 - 26,732,932 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tspan5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475726,557,898 - 26,733,209 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475726,558,052 - 26,732,932 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TSPAN5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38498,470,367 - 98,658,611 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl498,470,367 - 98,658,611 (-)EnsemblGRCh38hg38GRCh38
GRCh37499,391,518 - 99,579,762 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36499,612,421 - 99,798,750 (-)NCBINCBI36Build 36hg18NCBI36
Celera496,686,187 - 96,874,635 (-)NCBICelera
Cytogenetic Map4q23NCBI
HuRef495,128,912 - 95,317,094 (-)NCBIHuRef
CHM1_1499,368,380 - 99,556,673 (-)NCBICHM1_1
T2T-CHM13v2.04101,785,330 - 101,973,565 (-)NCBIT2T-CHM13v2.0
Tspan5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393138,447,609 - 138,610,194 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3138,447,956 - 138,613,666 (+)EnsemblGRCm39 Ensembl
GRCm383138,741,848 - 138,904,433 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,742,195 - 138,907,905 (+)EnsemblGRCm38mm10GRCm38
MGSCv373138,405,159 - 138,567,388 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,679,582 - 138,841,811 (+)NCBIMGSCv36mm8
Celera3145,169,944 - 145,332,005 (+)NCBICelera
Cytogenetic Map3H1NCBI
cM Map364.42NCBI
Tspan5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,967,521 - 230,139,012 (+)NCBIGRCr8
mRatBN7.22227,294,180 - 227,469,361 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2227,294,217 - 227,465,664 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2235,044,298 - 235,207,548 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,944,059 - 233,107,310 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,808,665 - 227,971,910 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02244,058,186 - 244,224,059 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2244,058,186 - 244,224,058 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02262,587,481 - 262,753,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42236,314,737 - 236,487,072 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12236,436,906 - 236,471,800 (+)NCBI
Celera2219,449,291 - 219,612,375 (+)NCBICelera
Cytogenetic Map2q44NCBI
Tspan5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554058,725,761 - 8,759,785 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554058,725,761 - 8,759,784 (-)NCBIChiLan1.0ChiLan1.0
TSPAN5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2396,537,654 - 96,718,544 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1496,815,612 - 96,994,454 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0490,872,988 - 91,052,345 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14101,536,950 - 101,717,526 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4101,536,950 - 101,717,228 (-)Ensemblpanpan1.1panPan2
TSPAN5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13220,707,449 - 20,878,441 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3220,709,539 - 20,878,426 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3221,053,555 - 21,228,770 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03220,890,676 - 21,061,654 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3220,890,676 - 21,061,716 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13220,859,415 - 21,029,584 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03220,685,159 - 20,855,851 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03219,041,028 - 19,211,757 (+)NCBIUU_Cfam_GSD_1.0
Tspan5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530120,832,188 - 20,999,948 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493671749,752 - 217,654 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493671749,797 - 217,567 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8121,657,325 - 121,843,242 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18121,657,320 - 121,843,296 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28130,843,562 - 131,031,806 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1746,610,841 - 46,788,761 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl746,609,602 - 46,788,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603725,042,011 - 25,220,101 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005728   ⟹   ENSHGLP00000005656
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475726,557,898 - 26,733,209 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000005729   ⟹   ENSHGLP00000005657
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475726,557,898 - 26,611,580 (-)Ensembl
RefSeq Acc Id: XM_004848102   ⟹   XP_004848159
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475726,558,052 - 26,732,932 (-)NCBI
RefSeq Acc Id: XM_004848103   ⟹   XP_004848160
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475726,558,052 - 26,732,932 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004848159 (Get FASTA)   NCBI Sequence Viewer  
  XP_004848160 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07465 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005656
RefSeq Acc Id: XP_004848160   ⟸   XM_004848103
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004848159   ⟸   XM_004848102
- Peptide Label: isoform X1
- UniProtKB: G5BDV4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005656   ⟸   ENSHGLT00000005728
Ensembl Acc Id: ENSHGLP00000005657   ⟸   ENSHGLT00000005729


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004135 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005728 ENTREZGENE
Gene3D-CATH Tetraspanin UniProtKB/TrEMBL
InterPro Tetraspanin/Peripherin UniProtKB/TrEMBL
  Tetraspanin_animals UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/TrEMBL
NCBI Gene Tspan5 ENTREZGENE
PANTHER TETRASPANIN UniProtKB/TrEMBL
  TETRASPANIN-5 UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/TrEMBL
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE TM4_1 UniProtKB/TrEMBL
Superfamily-SCOP Tetraspanin UniProtKB/TrEMBL
UniProt G5BDV4 ENTREZGENE, UniProtKB/TrEMBL