Ttc8 (tetratricopeptide repeat domain 8) - Rat Genome Database

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Gene: Ttc8 (tetratricopeptide repeat domain 8) Heterocephalus glaber
Analyze
Symbol: Ttc8
Name: tetratricopeptide repeat domain 8
RGD ID: 18932801
Description: ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN axon guidance (ortholog); camera-type eye photoreceptor cell differentiation (ortholog); cilium assembly (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 8 (ortholog); fundus dystrophy (ortholog); FOUND IN BBSome (ortholog); centrosome (ortholog); ciliary membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: tetratricopeptide repeat protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473413,437,221 - 13,497,510 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473413,437,234 - 13,497,269 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:26763976   PMID:30032202  


Genomics

Comparative Map Data
Ttc8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473413,437,221 - 13,497,510 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473413,437,234 - 13,497,269 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TTC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381488,824,153 - 88,881,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1488,824,153 - 88,881,078 (+)EnsemblGRCh38hg38GRCh38
GRCh371489,290,497 - 89,347,423 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361488,360,731 - 88,414,088 (+)NCBINCBI36Build 36hg18NCBI36
Build 341488,360,730 - 88,414,087NCBI
Celera1469,339,325 - 69,392,681 (+)NCBICelera
Cytogenetic Map14q31.3NCBI
HuRef1469,465,840 - 69,519,171 (+)NCBIHuRef
CHM1_11489,228,786 - 89,282,145 (+)NCBICHM1_1
T2T-CHM13v2.01483,047,758 - 83,104,682 (+)NCBIT2T-CHM13v2.0
Ttc8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391298,886,796 - 98,949,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1298,886,833 - 98,949,497 (+)EnsemblGRCm39 Ensembl
GRCm381298,920,537 - 98,983,250 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1298,920,574 - 98,983,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712100,158,784 - 100,221,448 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361299,321,639 - 99,384,288 (+)NCBIMGSCv36mm8
Celera12100,146,253 - 100,210,179 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1249.88NCBI
Ttc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86123,927,657 - 124,025,354 (+)NCBIGRCr8
mRatBN7.26118,198,186 - 118,252,422 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6118,198,201 - 118,252,418 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6118,348,070 - 118,402,289 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06118,644,871 - 118,699,091 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06117,979,722 - 118,033,939 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06122,920,308 - 122,974,525 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6122,920,317 - 122,974,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06132,140,808 - 132,207,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46123,117,534 - 123,171,840 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16123,121,373 - 123,174,881 (+)NCBI
Celera6115,755,975 - 115,810,232 (+)NCBICelera
Cytogenetic Map6q32NCBI
Ttc8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543811,409,982 - 11,466,523 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543811,410,196 - 11,466,044 (+)NCBIChiLan1.0ChiLan1.0
TTC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21589,967,618 - 90,027,137 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11489,187,209 - 89,243,644 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01469,446,355 - 69,502,351 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11488,802,812 - 88,857,055 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1488,802,812 - 88,857,055 (+)Ensemblpanpan1.1panPan2
TTC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1860,061,670 - 60,115,464 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl860,061,732 - 60,115,075 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha859,641,066 - 59,693,906 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0860,332,658 - 60,386,187 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl860,332,402 - 60,386,190 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1860,013,742 - 60,066,541 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0860,063,485 - 60,116,262 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0860,391,356 - 60,444,177 (+)NCBIUU_Cfam_GSD_1.0
Ttc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864015,762,381 - 15,810,727 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648816,258,058 - 16,306,589 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648816,258,247 - 16,306,077 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7110,731,731 - 110,784,853 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17110,731,729 - 110,783,999 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27117,222,186 - 117,274,088 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12466,483,808 - 66,539,717 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2466,483,864 - 66,539,142 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605353,829,890 - 53,884,739 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019395   ⟹   ENSHGLP00000019204
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473413,437,221 - 13,497,510 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000019396   ⟹   ENSHGLP00000019205
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473413,437,250 - 13,497,510 (-)Ensembl
RefSeq Acc Id: NM_001310243   ⟹   NP_001297172
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473413,437,234 - 13,497,269 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001297172 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AIZ09078 (Get FASTA)   NCBI Sequence Viewer  
  EHB09110 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019204
  ENSHGLP00100029083
Reference Protein Sequences
RefSeq Acc Id: NP_001297172   ⟸   NM_001310243
- UniProtKB: A0A0A7HRU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019204   ⟸   ENSHGLT00000019395
RefSeq Acc Id: ENSHGLP00000019205   ⟸   ENSHGLT00000019396


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013781 Ensembl, ENTREZGENE
  ENSHGLG00100033543 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000019395 ENTREZGENE
  ENSHGLT00100043055 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro BBS8 UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
KEGG Report hgl:101717584 UniProtKB/TrEMBL
NCBI Gene Ttc8 ENTREZGENE
PANTHER PTHR44177 UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN 8 UniProtKB/TrEMBL
Pfam TPR_16 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A0A7HRU7 ENTREZGENE, UniProtKB/TrEMBL