Ntmt2 (N-terminal Xaa-Pro-Lys N-methyltransferase 2) - Rat Genome Database

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Gene: Ntmt2 (N-terminal Xaa-Pro-Lys N-methyltransferase 2) Heterocephalus glaber
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Symbol: Ntmt2
Name: N-terminal Xaa-Pro-Lys N-methyltransferase 2
RGD ID: 18932551
Description: ENCODES a protein that exhibits N-terminal protein N-methyltransferase activity (ortholog); INVOLVED IN N-terminal protein amino acid methylation (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); gastrointestinal stromal tumor (ortholog); Marfanoid Mental Retardation Syndrome, Autosomal (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha N-terminal protein methyltransferase 1B; methyltransferase like 11B; Mettl11b
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248267,938,688 - 7,948,369 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ntmt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248267,938,688 - 7,948,369 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NTMT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381170,145,959 - 170,168,866 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1170,145,959 - 170,168,866 (+)EnsemblGRCh38hg38GRCh38
GRCh371170,115,100 - 170,138,007 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,381,873 - 168,403,522 (+)NCBINCBI36Build 36hg18NCBI36
Celera1143,225,003 - 143,246,729 (+)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1141,338,644 - 141,360,374 (+)NCBIHuRef
CHM1_11171,537,509 - 171,559,238 (+)NCBICHM1_1
T2T-CHM13v2.01169,501,867 - 169,524,770 (+)NCBIT2T-CHM13v2.0
Ntmt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,529,415 - 163,552,801 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1163,529,825 - 163,552,801 (-)EnsemblGRCm39 Ensembl
GRCm381163,702,993 - 163,725,232 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1163,702,256 - 163,725,232 (-)EnsemblGRCm38mm10GRCm38
MGSCv371165,633,124 - 165,655,363 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361165,539,692 - 165,561,837 (-)NCBIMGSCv36mm8
Celera1166,151,346 - 166,171,120 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map171.0NCBI
Ntmt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81378,585,663 - 78,627,144 (-)NCBIGRCr8
mRatBN7.21376,050,683 - 76,093,972 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1376,053,127 - 76,093,972 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1378,671,188 - 78,712,033 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01379,973,844 - 80,014,761 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01377,228,406 - 77,269,323 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01381,987,877 - 82,027,781 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1381,988,926 - 82,006,005 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01386,868,523 - 86,886,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41379,460,482 - 79,475,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1375,787,990 - 75,828,691 (-)NCBICelera
Cytogenetic Map13q22NCBI
Ntmt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554626,450,063 - 6,473,919 (+)NCBIChiLan1.0ChiLan1.0
NTMT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2179,592,643 - 79,616,241 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1179,266,074 - 79,289,687 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01145,635,789 - 145,658,564 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11149,352,738 - 149,374,488 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1149,352,738 - 149,374,488 (+)Ensemblpanpan1.1panPan2
NTMT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1728,520,322 - 28,543,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl728,524,761 - 28,544,379 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha728,050,008 - 28,075,309 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0728,319,994 - 28,345,331 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl728,326,278 - 28,345,227 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1728,168,977 - 28,194,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0728,204,127 - 28,229,336 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0728,440,703 - 28,466,048 (-)NCBIUU_Cfam_GSD_1.0
Ntmt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934498,710,607 - 98,752,196 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648116,582,901 - 16,598,504 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648116,582,352 - 16,598,385 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NTMT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl480,857,344 - 80,877,566 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1480,854,850 - 80,932,412 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2488,437,293 - 88,460,702 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NTMT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12558,898,029 - 58,919,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2558,898,262 - 58,919,292 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605560,552,178 - 60,574,449 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013065745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01082645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_013065745   ⟹   XP_012921199
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248267,938,688 - 7,948,369 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012921199 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_012921199   ⟸   XM_013065745
- UniProtKB: A0AAX6QMP5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
NCBI Gene Mettl11b ENTREZGENE
UniProt A0AAX6QMP5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-05-26 Ntmt2  N-terminal Xaa-Pro-Lys N-methyltransferase 2  Mettl11b  methyltransferase like 11B  Symbol and/or name change 5135510 APPROVED