Ipo8 (importin 8) - Rat Genome Database

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Gene: Ipo8 (importin 8) Heterocephalus glaber
Analyze
Symbol: Ipo8
Name: importin 8
RGD ID: 18932162
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN intracellular protein transport (inferred); protein import into nucleus (inferred); ASSOCIATED WITH genetic disease (ortholog); VISS syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: importin-8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247785,099,647 - 5,195,012 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247785,099,360 - 5,196,880 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ipo8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247785,099,647 - 5,195,012 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247785,099,360 - 5,196,880 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IPO8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381230,628,988 - 30,695,869 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1230,628,988 - 30,695,869 (-)EnsemblGRCh38hg38GRCh38
GRCh371230,781,922 - 30,848,803 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361230,673,189 - 30,740,018 (-)NCBINCBI36Build 36hg18NCBI36
Build 341230,673,189 - 30,740,018NCBI
Celera1235,924,748 - 35,991,765 (-)NCBICelera
Cytogenetic Map12p11.21NCBI
HuRef1230,547,280 - 30,614,305 (-)NCBIHuRef
CHM1_11230,746,941 - 30,813,955 (-)NCBICHM1_1
T2T-CHM13v2.01230,503,650 - 30,570,532 (-)NCBIT2T-CHM13v2.0
Ipo8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396148,672,181 - 148,732,977 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6148,672,181 - 148,732,965 (-)EnsemblGRCm39 Ensembl
GRCm386148,770,683 - 148,832,931 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6148,770,683 - 148,831,467 (-)EnsemblGRCm38mm10GRCm38
MGSCv376148,719,206 - 148,779,989 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366148,727,854 - 148,788,637 (-)NCBIMGSCv36mm8
Celera6151,807,825 - 151,869,431 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map678.57NCBI
Ipo8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84183,460,583 - 183,529,259 (-)NCBIGRCr8
mRatBN7.24181,729,216 - 181,793,672 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4181,729,220 - 181,793,161 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4187,999,563 - 188,064,053 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04183,784,091 - 183,848,583 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04182,404,583 - 182,469,077 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04183,228,688 - 183,295,253 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4183,229,985 - 183,293,999 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04247,359,871 - 247,424,869 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4170,197,109 - 170,259,830 (-)NCBICelera
Cytogenetic Map4q44NCBI
Ipo8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555054,490,598 - 4,575,213 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555054,490,738 - 4,574,969 (+)NCBIChiLan1.0ChiLan1.0
IPO8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21066,086,749 - 66,157,526 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11266,086,888 - 66,153,912 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01255,588,898 - 55,655,894 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11258,216,536 - 58,282,985 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1258,216,536 - 58,282,985 (+)Ensemblpanpan1.1panPan2
IPO8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12717,568,938 - 17,640,719 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2717,568,937 - 17,638,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2728,778,208 - 28,849,711 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02717,751,925 - 17,823,426 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2717,751,905 - 17,823,419 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12717,561,215 - 17,632,884 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02717,592,139 - 17,663,736 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02728,930,300 - 29,001,855 (-)NCBIUU_Cfam_GSD_1.0
LOC101961741
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494578,176,690 - 78,242,056 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366075,009,972 - 5,159,341 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IPO8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl543,099,749 - 43,182,803 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1543,099,749 - 43,182,807 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2546,786,263 - 46,869,197 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IPO8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11130,314,477 - 30,381,306 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1130,314,201 - 30,381,241 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660694,617,262 - 4,684,748 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000016279   ⟹   ENSHGLP00000016110
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247785,099,647 - 5,195,012 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000016280   ⟹   ENSHGLP00000016111
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247785,099,647 - 5,152,673 (+)Ensembl
RefSeq Acc Id: XM_004855062   ⟹   XP_004855119
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247785,099,360 - 5,196,880 (+)NCBI
RefSeq Acc Id: XM_021236571   ⟹   XP_021092230
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247785,099,779 - 5,196,880 (+)NCBI
RefSeq Acc Id: XM_021236572   ⟹   XP_021092231
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247785,099,361 - 5,196,880 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855119 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092230 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092231 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016110
Reference Protein Sequences
RefSeq Acc Id: XP_004855119   ⟸   XM_004855062
- Peptide Label: isoform X1
- UniProtKB: G5BLL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092231   ⟸   XM_021236572
- Peptide Label: isoform X2
- UniProtKB: G5BLL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092230   ⟸   XM_021236571
- Peptide Label: isoform X2
- UniProtKB: G5BLL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000016111   ⟸   ENSHGLT00000016280
RefSeq Acc Id: ENSHGLP00000016110   ⟸   ENSHGLT00000016279


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011526 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000016279 ENTREZGENE
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  XPO2_central UniProtKB/TrEMBL
NCBI Gene Ipo8 ENTREZGENE
PANTHER IMPORTIN-7, 8, 11 UniProtKB/TrEMBL
  IMPORTIN-8 UniProtKB/TrEMBL
Pfam Cse1 UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
UniProt G5BLL5 ENTREZGENE, UniProtKB/TrEMBL