Parp6 (poly(ADP-ribose) polymerase family member 6) - Rat Genome Database

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Gene: Parp6 (poly(ADP-ribose) polymerase family member 6) Heterocephalus glaber
Analyze
Symbol: Parp6
Name: poly(ADP-ribose) polymerase family member 6
RGD ID: 18929838
Description: ENCODES a protein that exhibits NAD+- protein-aspartate ADP-ribosyltransferase activity (ortholog); NAD+- protein-cysteine ADP-ribosyltransferase activity (ortholog); INVOLVED IN positive regulation of dendrite morphogenesis (ortholog); protein auto-ADP-ribosylation (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Tay-Sachs disease (ortholog); FOUND IN endoplasmic reticulum tubular network (inferred); membrane (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly (ADP-ribose) polymerase 6; Poly [ADP-ribose] polymerase 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,760,638 - 1,790,330 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Parp6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,760,638 - 1,790,330 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PARP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381572,241,181 - 72,272,554 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1572,241,181 - 72,272,999 (-)EnsemblGRCh38hg38GRCh38
GRCh371572,533,522 - 72,564,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361570,320,576 - 70,350,682 (-)NCBINCBI36Build 36hg18NCBI36
Build 341570,320,593 - 70,350,446NCBI
Celera1549,419,859 - 49,449,959 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1549,364,085 - 49,394,162 (-)NCBIHuRef
CHM1_11572,651,663 - 72,681,766 (-)NCBICHM1_1
T2T-CHM13v2.01570,057,855 - 70,089,700 (-)NCBIT2T-CHM13v2.0
Parp6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39959,524,473 - 59,557,573 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl959,524,567 - 59,557,568 (+)EnsemblGRCm39 Ensembl
GRCm38959,617,147 - 59,650,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl959,617,284 - 59,650,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv37959,465,091 - 59,498,076 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36959,415,290 - 59,448,291 (+)NCBIMGSCv36mm8
Celera956,844,243 - 56,877,403 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.02NCBI
Parp6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8868,912,393 - 68,944,904 (+)NCBIGRCr8
mRatBN7.2860,016,594 - 60,049,108 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl860,016,877 - 60,049,108 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx865,539,104 - 65,571,364 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0863,812,031 - 63,844,289 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0861,681,479 - 61,713,740 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0864,439,933 - 64,472,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,440,214 - 64,472,443 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0864,202,946 - 64,235,456 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4863,445,529 - 63,477,760 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1863,465,708 - 63,496,809 (+)NCBI
Celera859,458,506 - 59,492,106 (+)NCBICelera
Cytogenetic Map8q24NCBI
Parp6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554504,863,564 - 4,901,847 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554504,863,713 - 4,900,509 (+)NCBIChiLan1.0ChiLan1.0
PARP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21661,505,390 - 61,536,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11565,669,661 - 65,703,868 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01551,191,718 - 51,223,312 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11569,955,568 - 69,987,059 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1569,955,568 - 69,987,061 (-)Ensemblpanpan1.1panPan2
PARP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13035,745,384 - 35,773,597 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3035,682,330 - 35,710,515 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03035,950,229 - 35,978,396 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3035,950,229 - 35,978,389 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13035,903,113 - 35,931,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03035,931,174 - 35,959,355 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03036,186,002 - 36,214,173 (-)NCBIUU_Cfam_GSD_1.0
Parp6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640113,777,168 - 113,808,140 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647131,625,231 - 31,655,208 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647131,625,231 - 31,656,204 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12611,182,436 - 11,214,490 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2611,182,424 - 11,214,728 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048130,361,169 - 130,393,103 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000010556   ⟹   ENSHGLP00000010440
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247811,760,638 - 1,790,330 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000010557   ⟹   ENSHGLP00000010441
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247811,760,638 - 1,788,866 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000010558   ⟹   ENSHGLP00000010442
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247811,765,330 - 1,788,840 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000010559   ⟹   ENSHGLP00000010443
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247811,765,929 - 1,789,945 (+)Ensembl
RefSeq Acc Id: XM_004855527   ⟹   XP_004855584
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBI
RefSeq Acc Id: XM_004855528   ⟹   XP_004855585
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBI
RefSeq Acc Id: XM_004855529   ⟹   XP_004855586
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBI
RefSeq Acc Id: XM_004855530   ⟹   XP_004855587
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBI
RefSeq Acc Id: XM_021236970   ⟹   XP_021092629
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBI
RefSeq Acc Id: XM_021236971   ⟹   XP_021092630
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,790,207 (+)NCBI
RefSeq Acc Id: XM_021236972   ⟹   XP_021092631
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,789,526 (+)NCBI
RefSeq Acc Id: XR_002386405
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,789,885 (+)NCBI
RefSeq Acc Id: XR_002386406
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247811,760,613 - 1,789,493 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021092630   ⟸   XM_021236971
- Peptide Label: isoform X1
- UniProtKB: G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092629   ⟸   XM_021236970
- Peptide Label: isoform X1
- UniProtKB: G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855584   ⟸   XM_004855527
- Peptide Label: isoform X1
- UniProtKB: G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855585   ⟸   XM_004855528
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JH24 (UniProtKB/TrEMBL),   G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855586   ⟸   XM_004855529
- Peptide Label: isoform X3
- UniProtKB: G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855587   ⟸   XM_004855530
- Peptide Label: isoform X4
- UniProtKB: G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092631   ⟸   XM_021236972
- Peptide Label: isoform X5
- UniProtKB: G5BHB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000010441   ⟸   ENSHGLT00000010557
RefSeq Acc Id: ENSHGLP00000010440   ⟸   ENSHGLT00000010556
RefSeq Acc Id: ENSHGLP00000010442   ⟸   ENSHGLT00000010558
RefSeq Acc Id: ENSHGLP00000010443   ⟸   ENSHGLT00000010559


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007492 Ensembl, ENTREZGENE
  ENSHGLG00100010688 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000010556 ENTREZGENE
  ENSHGLT00000010557 ENTREZGENE
  ENSHGLT00000010559 ENTREZGENE
  ENSHGLT00100014613 UniProtKB/TrEMBL
Gene3D-CATH 3.90.228.10 UniProtKB/TrEMBL
InterPro Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
NCBI Gene Parp6 ENTREZGENE
PANTHER POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP6 UniProtKB/TrEMBL
Pfam PARP UniProtKB/TrEMBL
PROSITE PARP_CATALYTIC UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
UniProt A0A0P6JH24 ENTREZGENE, UniProtKB/TrEMBL
  G5BHB2 ENTREZGENE, UniProtKB/TrEMBL