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Gene: Eml1 (EMAP like 1) Heterocephalus glaber

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Symbol:

Eml1

Name:

EMAP like 1

RGD ID:

18929068

Description:

ENCODES a protein that exhibits tubulin binding (ortholog); INVOLVED IN brain development (ortholog); hematopoietic progenitor cell differentiation (ortholog); mitotic spindle organization (ortholog); ASSOCIATED WITH congenital nervous system abnormality (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); microtubule cytoskeleton (ortholog); mitotic spindle midzone (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

echinoderm microtubule associated protein like 1; echinoderm microtubule-associated protein-like 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EML1 (EMAP like 1)	NCBI	Ortholog
Mus musculus (house mouse):	Eml1 (echinoderm microtubule associated protein like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Eml1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Eml1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EML1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EML1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Eml1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EML1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EML1 (EMAP like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	4,089,986 - 4,236,776 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	4,090,077 - 4,150,706 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	epilepsy		ISO	Eml1 (Rattus norvegicus)	9068941		RGD	PMID:9236234 and REF_RGD_ID:597538480
Eml1	Naked Mole-Rat	skin melanoma	disease_progression	ISO	EML1 (Homo sapiens)	9068941	DNA:SNP: :rs10151787 (A>G)	RGD	PMID:34249459 and REF_RGD_ID:597538489

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	genetic disease		ISO	EML1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868 and PMID:28492532
Eml1	Naked Mole-Rat	subcortical band heterotopia		ISO	EML1 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:24859200 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	congenital nervous system abnormality		ISO	Eml1 (Mus musculus)	9068941		MouseDO

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	subcortical band heterotopia		ISO	EML1 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	brain development	involved_in	ISO	EML1 (Homo sapiens)	9068941	PMID:24859200	UniProt	PMID:24859200
Eml1	Naked Mole-Rat	brain development	involved_in	ISO	Eml1 (Mus musculus)	9068941	PMID:24859200	UniProt	PMID:24859200
Eml1	Naked Mole-Rat	hematopoietic progenitor cell differentiation	acts_upstream_of_or_within	ISO	MGI:1343184	9068941	PMID:24029230	MGI	PMID:24029230
Eml1	Naked Mole-Rat	microtubule cytoskeleton organization	involved_in	IEA	PANTHER:PTN000347184	150520179		TreeGrafter	GO_REF:0000118
Eml1	Naked Mole-Rat	mitotic spindle organization	involved_in	ISO	Eml1 (Mus musculus)	9068941	PMID:24859200	UniProt	PMID:24859200
Eml1	Naked Mole-Rat	neuroblast proliferation	involved_in	ISO	Eml1 (Mus musculus)	9068941	PMID:24859200	UniProt	PMID:24859200

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	cytosol	located_in	ISO	Eml1 (Mus musculus)	9068941	PMID:24859200	UniProt	PMID:24859200
Eml1	Naked Mole-Rat	microtubule	located_in	IEA	UniProtKB-KW:KW-0493	150520179		UniProt	GO_REF:0000043
Eml1	Naked Mole-Rat	microtubule cytoskeleton	located_in	ISO	EML1 (Homo sapiens)	9068941	PMID:24859200	UniProt	PMID:24859200
Eml1	Naked Mole-Rat	mitotic spindle	located_in	IEA	PANTHER:PTN000347184	150520179		TreeGrafter	GO_REF:0000118
Eml1	Naked Mole-Rat	mitotic spindle midzone	located_in	ISO	Eml1 (Mus musculus)	9068941	PMID:24859200	UniProt	PMID:24859200
Eml1	Naked Mole-Rat	mitotic spindle pole	located_in	ISO	Eml1 (Mus musculus)	9068941	PMID:24859200	UniProt	PMID:24859200

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml1	Naked Mole-Rat	microtubule binding	enables	IEA	PANTHER:PTN000347184	150520179		TreeGrafter	GO_REF:0000118
Eml1	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:Q9H9L3	9068941	PMID:16189514 and PMID:19060904	IntAct	PMID:16189514 and PMID:19060904
Eml1	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:P13473-2 more ...	9068941	PMID:32814053	IntAct	PMID:32814053
Eml1	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:P51114	9068941	PMID:21653829	IntAct	PMID:21653829
Eml1	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:Q9Y266	9068941	PMID:25036637 and PMID:33961781	IntAct	PMID:25036637 and PMID:33961781
Eml1	Naked Mole-Rat	tubulin binding	enables	ISO	EML1 (Homo sapiens)	9068941	PMID:24706829	UniProt	PMID:24706829

PMID:30032202

Eml1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	4,089,986 - 4,236,776 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	4,090,077 - 4,150,706 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

EML1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	99,737,722 - 99,942,060 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	99,737,693 - 99,942,060 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	100,204,059 - 100,408,397 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	99,329,498 - 99,478,150 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	99,329,497 - 99,478,146	NCBI
Celera	14	80,314,618 - 80,463,271 (+)	NCBI		Celera
Cytogenetic Map	14	q32.2	NCBI
HuRef	14	80,500,729 - 80,591,998 (+)	NCBI		HuRef
CHM1_1	14	100,197,512 - 100,346,159 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	93,969,151 - 94,174,609 (+)	NCBI		T2T-CHM13v2.0

Eml1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	108,337,265 - 108,505,835 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	108,337,216 - 108,505,876 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	108,371,002 - 108,539,576 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	108,370,957 - 108,539,617 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	109,648,865 - 109,777,774 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	108,818,764 - 108,987,383 (+)	NCBI		MGSCv36	mm8
MGSCv36	12	102,632,098 - 102,805,540 (+)	NCBI		MGSCv36	mm8
Celera	12	109,653,344 - 109,775,028 (+)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	59.46	NCBI

Eml1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	133,048,271 - 133,221,642 (+)	NCBI		GRCr8
mRatBN7.2	6	127,283,968 - 127,457,246 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	127,284,029 - 127,457,246 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	127,408,913 - 127,581,347 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	127,703,970 - 127,876,401 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	127,061,846 - 127,234,628 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	132,367,342 - 132,450,488 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	132,383,337 - 132,450,393 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	141,536,753 - 141,619,726 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	132,825,590 - 132,880,169 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	132,831,776 - 132,886,352 (+)	NCBI
Celera	6	124,926,667 - 125,013,010 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Eml1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	21,078,760 - 21,137,926 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	20,991,432 - 21,137,570 (+)	NCBI	ChiLan1.0	ChiLan1.0

EML1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	100,893,344 - 101,097,011 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	100,109,839 - 100,313,506 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	80,362,837 - 80,566,996 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	99,717,220 - 99,885,359 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	99,793,812 - 99,885,359 (+)	Ensembl	panpan1.1		panPan2

EML1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	68,139,741 - 68,295,363 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	68,216,857 - 68,294,080 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	67,628,246 - 67,816,902 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	68,391,782 - 68,580,690 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	68,391,815 - 68,580,640 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	68,052,800 - 68,241,854 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	68,119,216 - 68,308,068 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	68,516,950 - 68,705,827 (+)	NCBI		UU_Cfam_GSD_1.0

Eml1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	6,420,280 - 6,584,031 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936604	3,498,304 - 3,662,244 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936604	3,498,413 - 3,662,188 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EML1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	120,703,258 - 120,890,791 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	120,703,282 - 120,890,792 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

EML1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	77,694,931 - 77,907,574 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	77,694,971 - 77,907,909 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	64,834,630 - 65,042,702 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_004836971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_004836972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_004836973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021244406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01009133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GEBF01002472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSHGLT00000020255 ⟹ ENSHGLP00000020055

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624734	4,089,986 - 4,236,776 (-)	Ensembl

Ensembl Acc Id:

ENSHGLT00000020256 ⟹ ENSHGLP00000020056

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624734	4,089,986 - 4,236,776 (-)	Ensembl

RefSeq Acc Id:

XM_004836971 ⟹ XP_004837028

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624734	4,090,077 - 4,150,706 (-)	NCBI

RefSeq Acc Id:

XM_004836972 ⟹ XP_004837029

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624734	4,090,077 - 4,150,706 (-)	NCBI

RefSeq Acc Id:

XM_004836973 ⟹ XP_004837030

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624734	4,090,077 - 4,150,706 (-)	NCBI

RefSeq Acc Id:

XM_021244406 ⟹ XP_021100065

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624734	4,090,077 - 4,150,706 (-)	NCBI


Protein RefSeqs	XP_004837028	(Get FASTA)	NCBI Sequence Viewer
	XP_004837029	(Get FASTA)	NCBI Sequence Viewer
	XP_004837030	(Get FASTA)	NCBI Sequence Viewer
	XP_021100065	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSHGLP00000020055
	ENSHGLP00000020056
GenBank Protein	JAO01161	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_004837030 ⟸ XM_004836973
- Peptide Label:	isoform X4
- UniProtKB:	A0AAX6NU74 (UniProtKB/TrEMBL), A0A0P6JEW6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_004837028 ⟸ XM_004836971
- Peptide Label:	isoform X2
- UniProtKB:	A0AAX6NU44 (UniProtKB/TrEMBL), A0A0P6JEW6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_004837029 ⟸ XM_004836972
- Peptide Label:	isoform X3
- UniProtKB:	A0AAX6NU34 (UniProtKB/TrEMBL), A0A0P6JEW6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021100065 ⟸ XM_021244406
- Peptide Label:	isoform X1
- UniProtKB:	A0AAX6RSN1 (UniProtKB/TrEMBL), A0A0P6JEW6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSHGLP00000020055 ⟸ ENSHGLT00000020255

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000014366	Ensembl, ENTREZGENE
Ensembl Transcript	ENSHGLT00000020255	ENTREZGENE
	ENSHGLT00000020256	ENTREZGENE
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	HELP	UniProtKB/TrEMBL
	Quinoprotein_ADH-like_supfam	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD_repeat_EMAP	UniProtKB/TrEMBL
NCBI Gene	Eml1	ENTREZGENE
PANTHER	ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1	UniProtKB/TrEMBL
	WD-40 REPEAT PROTEIN	UniProtKB/TrEMBL
Pfam	HELP	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50998	UniProtKB/TrEMBL
UniProt	A0A0P6JEW6	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6NU34	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6NU44	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6NU74	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6RSN1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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