EML1 (EMAP like 1) - Rat Genome Database

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Gene: EML1 (EMAP like 1) Chlorocebus sabaeus
Analyze
Symbol: EML1
Name: EMAP like 1
RGD ID: 18672206
Description: ENCODES a protein that exhibits microtubule binding (inferred); tubulin binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); ASSOCIATED WITH congenital nervous system abnormality (ortholog); genetic disease (ortholog); subcortical band heterotopia (ortholog); FOUND IN cytoskeleton (inferred); cytosol (inferred); microtubule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: echinoderm microtubule associated protein like 1; echinoderm microtubule-associated protein-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,694,931 - 77,907,574 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,694,971 - 77,907,909 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605364,834,630 - 65,042,702 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EML1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,694,931 - 77,907,574 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,694,971 - 77,907,909 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605364,834,630 - 65,042,702 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
EML1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,737,722 - 99,942,060 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,737,693 - 99,942,060 (+)EnsemblGRCh38hg38GRCh38
GRCh3714100,204,059 - 100,408,397 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361499,329,498 - 99,478,150 (+)NCBINCBI36Build 36hg18NCBI36
Build 341499,329,497 - 99,478,146NCBI
Celera1480,314,618 - 80,463,271 (+)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1480,500,729 - 80,591,998 (+)NCBIHuRef
CHM1_114100,197,512 - 100,346,159 (+)NCBICHM1_1
T2T-CHM13v2.01493,969,151 - 94,174,609 (+)NCBIT2T-CHM13v2.0
Eml1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,337,265 - 108,505,835 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,337,216 - 108,505,876 (+)EnsemblGRCm39 Ensembl
GRCm3812108,371,002 - 108,539,576 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12108,370,957 - 108,539,617 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712109,648,865 - 109,777,774 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612108,818,764 - 108,987,383 (+)NCBIMGSCv36mm8
MGSCv3612102,632,098 - 102,805,540 (+)NCBIMGSCv36mm8
Celera12109,653,344 - 109,775,028 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.46NCBI
Eml1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86133,048,271 - 133,221,642 (+)NCBIGRCr8
mRatBN7.26127,283,968 - 127,457,246 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,284,029 - 127,457,246 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6127,408,913 - 127,581,347 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,703,970 - 127,876,401 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06127,061,846 - 127,234,628 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,367,342 - 132,450,488 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,383,337 - 132,450,393 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,536,753 - 141,619,726 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,825,590 - 132,880,169 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,831,776 - 132,886,352 (+)NCBI
Celera6124,926,667 - 125,013,010 (+)NCBICelera
Cytogenetic Map6q32NCBI
Eml1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543821,078,760 - 21,137,926 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543820,991,432 - 21,137,570 (+)NCBIChiLan1.0ChiLan1.0
EML1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215100,893,344 - 101,097,011 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114100,109,839 - 100,313,506 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,362,837 - 80,566,996 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,717,220 - 99,885,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1499,793,812 - 99,885,359 (+)Ensemblpanpan1.1panPan2
EML1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1868,139,741 - 68,295,363 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl868,216,857 - 68,294,080 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,628,246 - 67,816,902 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0868,391,782 - 68,580,690 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,391,815 - 68,580,640 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1868,052,800 - 68,241,854 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0868,119,216 - 68,308,068 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,516,950 - 68,705,827 (+)NCBIUU_Cfam_GSD_1.0
Eml1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,420,280 - 6,584,031 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,498,304 - 3,662,244 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,498,413 - 3,662,188 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EML1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,703,258 - 120,890,791 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17120,703,282 - 120,890,792 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Eml1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247344,089,986 - 4,236,776 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247344,090,077 - 4,150,706 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 32 55
Low 4 11 5
Below cutoff 7

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007987805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007987814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000008488   ⟹   ENSCSAP00000006632
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2477,694,971 - 77,907,909 (+)Ensembl
RefSeq Acc Id: XM_037984479   ⟹   XP_037840407
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605364,890,752 - 65,042,702 (+)NCBI
RefSeq Acc Id: XM_037984480   ⟹   XP_037840408
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605364,834,631 - 65,042,702 (+)NCBI
RefSeq Acc Id: XM_037984481   ⟹   XP_037840409
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605364,890,753 - 65,042,160 (+)NCBI
RefSeq Acc Id: XM_037984482   ⟹   XP_037840410
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605364,921,282 - 65,042,702 (+)NCBI
RefSeq Acc Id: XM_037984484   ⟹   XP_037840412
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605364,834,630 - 65,042,160 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037840407 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840408 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840409 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840410 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840412 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006632.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000006632   ⟸   ENSCSAT00000008488
RefSeq Acc Id: XP_037840412   ⟸   XM_037984484
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037840408   ⟸   XM_037984480
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RDE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037840407   ⟸   XM_037984479
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037840409   ⟸   XM_037984481
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037840410   ⟸   XM_037984482
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010399 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008488.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro HELP UniProtKB/TrEMBL
  Quinoprotein_ADH-like_supfam UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene EML1 ENTREZGENE
PANTHER ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 UniProtKB/TrEMBL
  WD-40 REPEAT PROTEIN UniProtKB/TrEMBL
Pfam HELP UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF50998 UniProtKB/TrEMBL
UniProt A0A0D9RDE3 ENTREZGENE, UniProtKB/TrEMBL