Mesp2 (mesoderm posterior bHLH transcription factor 2) - Rat Genome Database

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Gene: Mesp2 (mesoderm posterior bHLH transcription factor 2) Heterocephalus glaber
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Symbol: Mesp2
Name: mesoderm posterior bHLH transcription factor 2
RGD ID: 18928251
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN mesodermal cell migration (ortholog); Notch signaling pathway (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); spondylocostal dysostosis 1 (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mesoderm posterior 2 homolog; mesoderm posterior protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476816,832,008 - 16,834,697 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_00462476816,830,795 - 16,834,798 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
JBrowse:




References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mesp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476816,832,008 - 16,834,697 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_00462476816,830,795 - 16,834,798 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
MESP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,776,332 - 89,778,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,760,591 - 89,778,754 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371590,319,563 - 90,321,985 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,120,593 - 88,122,989 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1566,722,377 - 66,724,773 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1566,432,299 - 66,434,671 (+)NCBIHuRef
CHM1_11590,160,596 - 90,162,992 (+)NCBICHM1_1
T2T-CHM13v2.01587,532,244 - 87,534,642 (+)NCBIT2T-CHM13v2.0
Mesp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,460,475 - 79,463,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,460,475 - 79,463,187 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38779,810,727 - 79,813,431 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,810,727 - 79,813,439 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37786,955,613 - 86,958,317 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36779,684,240 - 79,686,946 (+)NCBIMGSCv36mm8
Celera777,209,936 - 77,212,640 (+)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.18NCBI
Mesp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,165,914 - 143,168,520 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1143,165,849 - 143,168,511 (+)EnsemblGRCr8
mRatBN7.21133,756,601 - 133,759,207 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,756,601 - 133,759,198 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1141,665,735 - 141,668,332 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,835,140 - 148,837,737 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,752,836 - 141,755,433 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1142,159,991 - 142,162,588 (+)NCBI
Lyon_Normotensive1147,098,440 - 147,101,037 (+)NCBI
Lyon_Hypertensive1143,758,261 - 143,760,858 (+)NCBI
F344_StmMcwi1142,296,809 - 142,299,406 (+)NCBI
Rnor_6.01141,550,633 - 141,553,239 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,550,633 - 141,553,230 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01142,511,695 - 142,514,301 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41135,590,020 - 135,592,626 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1125,819,906 - 125,822,512 (+)NCBICelera
RGSC_v3.11135,668,399 - 135,670,416 (+)NCBI
Cytogenetic Map1q31NCBI
Mesp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,448,377 - 15,450,800 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495541615,447,959 - 15,450,209 (-)NCBIChiLan1.0ChiLan1.0
MESP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21679,327,064 - 79,330,074 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11583,029,385 - 83,031,781 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01568,470,528 - 68,473,209 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,673,337 - 87,675,698 (+)NCBIPanPan1.1PanPan1.1panPan2
MESP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,757,581 - 52,759,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,756,836 - 52,760,004 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha355,391,161 - 55,393,462 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0353,173,970 - 53,176,273 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,173,970 - 53,176,717 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,695,769 - 52,698,068 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,905,716 - 52,908,057 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,246,094 - 53,248,395 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mesp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap15136,178,982 - 136,181,546 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_024408640130,777,038 - 130,779,436 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,555,084 - 15,557,060 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648315,555,084 - 15,557,060 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MESP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl755,342,935 - 55,345,879 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1755,341,941 - 55,345,824 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,231,273 - 60,234,781 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MESP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12916,609,367 - 16,611,704 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605938,495,779 - 38,498,116 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1298,313,022 - 8,316,116 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Mesp2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12120,430,946 - 120,433,561 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004852774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01048260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000013038   ⟹   ENSHGLP00000012901
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476816,830,795 - 16,834,798 (+)Ensembl
RefSeq Acc Id: XM_004852774   ⟹   XP_004852831
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476816,832,008 - 16,834,697 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004852831 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012901
RefSeq Acc Id: XP_004852831   ⟸   XM_004852774
- UniProtKB: A0AAX6PIG8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000012901   ⟸   ENSHGLT00000013038


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009224 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013038 ENTREZGENE
Gene3D-CATH Helix-loop-helix DNA-binding domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Mesogenin/MesP UniProtKB/TrEMBL
KEGG Report hgl:101705671 UniProtKB/TrEMBL
NCBI Gene Mesp2 ENTREZGENE
PANTHER IP14615P UniProtKB/TrEMBL
  MESODERM POSTERIOR PROTEIN 2 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP HLH, helix-loop-helix DNA-binding domain UniProtKB/TrEMBL
UniProt A0AAX6PIG8 ENTREZGENE, UniProtKB/TrEMBL