Amdhd1 (amidohydrolase domain containing 1) - Rat Genome Database

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Gene: Amdhd1 (amidohydrolase domain containing 1) Heterocephalus glaber
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Symbol: Amdhd1
Name: amidohydrolase domain containing 1
RGD ID: 18925795
Description: ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (inferred); imidazolonepropionase activity (inferred); INVOLVED IN L-histidine catabolic process (inferred); L-histidine catabolic process to glutamate and formamide (inferred); L-histidine catabolic process to glutamate and formate (inferred); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable imidazolonepropionase; Putative imidazolonepropionase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475011,352,368 - 11,377,694 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475011,352,368 - 11,377,329 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Amdhd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475011,352,368 - 11,377,694 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475011,352,368 - 11,377,329 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AMDHD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381295,943,331 - 95,968,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1295,943,331 - 95,968,720 (+)EnsemblGRCh38hg38GRCh38
GRCh371296,337,109 - 96,362,498 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361294,861,202 - 94,886,500 (+)NCBINCBI36Build 36hg18NCBI36
Celera1296,005,967 - 96,028,689 (+)NCBICelera
Cytogenetic Map12q23.1NCBI
HuRef1293,401,507 - 93,424,233 (+)NCBIHuRef
CHM1_11296,302,439 - 96,327,344 (+)NCBICHM1_1
T2T-CHM13v2.01295,919,901 - 95,942,718 (+)NCBIT2T-CHM13v2.0
Amdhd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391093,359,200 - 93,375,973 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1093,359,200 - 93,375,895 (-)EnsemblGRCm39 Ensembl
GRCm381093,523,338 - 93,540,111 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1093,523,338 - 93,540,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv371092,986,083 - 93,002,778 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361092,953,137 - 92,969,832 (-)NCBIMGSCv36mm8
Celera1095,509,267 - 95,526,553 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.54NCBI
Amdhd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8729,930,966 - 29,946,199 (-)NCBIGRCr8
mRatBN7.2728,043,923 - 28,059,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,043,716 - 28,059,156 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx730,034,284 - 30,049,520 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,196,501 - 32,211,738 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0731,971,373 - 31,986,628 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,362,635 - 34,406,282 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,361,633 - 34,406,318 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0734,427,627 - 34,471,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4730,557,367 - 30,572,599 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1730,577,176 - 30,592,879 (-)NCBI
Celera725,143,208 - 25,186,848 (-)NCBICelera
Cytogenetic Map7q13NCBI
Amdhd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540532,283,413 - 32,308,230 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540532,281,726 - 32,308,230 (+)NCBIChiLan1.0ChiLan1.0
AMDHD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210104,016,375 - 104,039,599 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112104,012,765 - 104,035,989 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01293,534,881 - 93,557,762 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11296,923,879 - 96,946,507 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1296,923,879 - 96,946,507 (+)Ensemblpanpan1.1panPan2
AMDHD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11535,741,190 - 35,761,848 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1535,692,161 - 35,760,978 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1536,132,469 - 36,148,396 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01536,411,148 - 36,426,868 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1536,410,952 - 36,427,134 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11535,684,044 - 35,699,752 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01535,778,577 - 35,794,280 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01536,041,752 - 36,057,471 (+)NCBIUU_Cfam_GSD_1.0
Amdhd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494524,185,003 - 24,201,632 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650712,033,797 - 12,050,118 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650712,033,804 - 12,049,210 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMDHD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl587,551,913 - 87,569,305 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1587,551,887 - 87,569,271 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2591,755,963 - 91,765,895 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AMDHD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11191,319,330 - 91,341,466 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1191,319,409 - 91,341,559 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037153,787,157 - 153,810,144 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012142   ⟹   ENSHGLP00000012010
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475011,352,368 - 11,377,694 (-)Ensembl
RefSeq Acc Id: XM_004844912   ⟹   XP_004844969
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475011,352,368 - 11,377,329 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004844969 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15141 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012010
RefSeq Acc Id: XP_004844969   ⟸   XM_004844912
- UniProtKB: G5C0T0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000012010   ⟸   ENSHGLT00000012142


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008602 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000012142 ENTREZGENE
Gene3D-CATH 2.30.40.10 UniProtKB/TrEMBL
  Metal-dependent hydrolases UniProtKB/TrEMBL
InterPro Amidohydro-rel UniProtKB/TrEMBL
  HutI UniProtKB/TrEMBL
  Metal-dep_hydrolase_composite UniProtKB/TrEMBL
  Metal_Hydrolase UniProtKB/TrEMBL
KEGG Report hgl:101700746 UniProtKB/TrEMBL
NCBI Gene Amdhd1 ENTREZGENE
PANTHER IMIDAZOLONEPROPIONASE-RELATED UniProtKB/TrEMBL
  PTHR42752 UniProtKB/TrEMBL
Pfam Amidohydro_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF51338 UniProtKB/TrEMBL
  SSF51556 UniProtKB/TrEMBL
UniProt G5C0T0 ENTREZGENE, UniProtKB/TrEMBL