Bcan (brevican) - Rat Genome Database

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Gene: Bcan (brevican) Heterocephalus glaber
Analyze
Symbol: Bcan
Name: brevican
RGD ID: 18925691
Description: ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: brevican core protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248851,820,105 - 1,832,510 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248851,816,591 - 1,829,971 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Bcan
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248851,820,105 - 1,832,510 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248851,816,591 - 1,829,971 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BCAN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,642,117 - 156,659,528 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,641,390 - 156,659,532 (+)EnsemblGRCh38hg38GRCh38
GRCh371156,611,909 - 156,629,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,878,364 - 154,895,944 (+)NCBINCBI36Build 36hg18NCBI36
Build 341153,424,812 - 153,442,391NCBI
Celera1129,682,549 - 129,700,133 (+)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1127,969,333 - 127,986,922 (+)NCBIHuRef
CHM1_11158,007,947 - 158,025,532 (+)NCBICHM1_1
T2T-CHM13v2.01155,778,497 - 155,795,916 (+)NCBIT2T-CHM13v2.0
Bcan
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,894,839 - 87,908,458 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl387,894,838 - 87,907,537 (-)EnsemblGRCm39 Ensembl
GRCm38387,987,531 - 88,002,175 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl387,987,531 - 88,000,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv37387,791,453 - 87,804,278 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,073,458 - 88,086,157 (-)NCBIMGSCv36mm8
Celera388,024,909 - 88,037,731 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.78NCBI
Bcan
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,752,333 - 175,765,766 (-)NCBIGRCr8
mRatBN7.22173,454,479 - 173,467,717 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,454,482 - 173,467,460 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,599,269 - 180,612,251 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,621,629 - 178,634,612 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02173,221,686 - 173,234,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02187,359,674 - 187,373,133 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,359,677 - 187,372,657 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,762,691 - 206,776,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,067,864 - 180,080,942 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,022,993 - 180,030,847 (-)NCBI
Celera2167,401,907 - 167,414,841 (-)NCBICelera
Cytogenetic Map2q34NCBI
Bcan
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,723,780 - 2,739,450 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,723,780 - 2,739,334 (+)NCBIChiLan1.0ChiLan1.0
BCAN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,185,075 - 93,204,399 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1192,919,574 - 92,938,939 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,985,310 - 132,003,068 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,808,783 - 135,826,344 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,808,783 - 135,826,344 (+)Ensemblpanpan1.1panPan2
BCAN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,313,578 - 41,330,178 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,313,579 - 41,330,178 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,800,863 - 40,817,472 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,176,717 - 41,193,313 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,176,718 - 41,248,421 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1740,958,653 - 40,975,224 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,011,623 - 41,028,215 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,295,291 - 41,311,883 (-)NCBIUU_Cfam_GSD_1.0
Bcan
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,785,957 - 26,798,152 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365805,816,359 - 5,828,126 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365805,816,196 - 5,828,531 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCAN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,432,330 - 93,450,831 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,432,331 - 93,450,895 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,095,832 - 102,114,192 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCAN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,203,546 - 7,221,108 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,203,378 - 7,220,973 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,499,085 - 6,516,895 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005896   ⟹   ENSHGLP00000005823
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248851,820,105 - 1,829,665 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000005897   ⟹   ENSHGLP00000005824
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248851,820,116 - 1,832,510 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000005898   ⟹   ENSHGLP00000005825
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248851,820,116 - 1,832,510 (+)Ensembl
RefSeq Acc Id: XM_004871231   ⟹   XP_004871288
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248851,816,591 - 1,829,971 (+)NCBI
RefSeq Acc Id: XM_004871232   ⟹   XP_004871289
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248851,816,591 - 1,829,971 (+)NCBI
RefSeq Acc Id: XM_021249350   ⟹   XP_021105009
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248851,816,591 - 1,829,971 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004871288 (Get FASTA)   NCBI Sequence Viewer  
  XP_004871289 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105009 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005823
GenBank Protein JAN98778 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004871288   ⟸   XM_004871231
- Peptide Label: isoform X1
- UniProtKB: G5AR83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004871289   ⟸   XM_004871232
- Peptide Label: isoform X3
- UniProtKB: G5AR83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021105009   ⟸   XM_021249350
- Peptide Label: isoform X2
- UniProtKB: G5AR83 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005824   ⟸   ENSHGLT00000005897
Ensembl Acc Id: ENSHGLP00000005825   ⟸   ENSHGLT00000005898
Ensembl Acc Id: ENSHGLP00000005823   ⟸   ENSHGLT00000005896


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004251 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005896 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.10.100.10 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/TrEMBL
  CTDL_fold UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  Hyaluronan_bind_Proteoglycan UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Link_dom UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/TrEMBL
NCBI Gene Bcan ENTREZGENE
PANTHER AGGRECAN/VERSICAN PROTEOGLYCAN UniProtKB/TrEMBL
  BREVICAN CORE PROTEIN UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  Lectin_C UniProtKB/TrEMBL
  Sushi UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
  Xlink UniProtKB/TrEMBL
PRINTS LINKMODULE UniProtKB/TrEMBL
PROSITE C_TYPE_LECTIN_1 UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
  LINK_1 UniProtKB/TrEMBL
  LINK_2 UniProtKB/TrEMBL
  SUSHI UniProtKB/TrEMBL
SMART CCP UniProtKB/TrEMBL
  CLECT UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  LINK UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP Complement control module/SCR domain UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF56436 UniProtKB/TrEMBL
UniProt A0A0P6J5F9_HETGA UniProtKB/TrEMBL
  G5AR83 ENTREZGENE, UniProtKB/TrEMBL