Lyar (Ly1 antibody reactive) - Rat Genome Database

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Gene: Lyar (Ly1 antibody reactive) Heterocephalus glaber
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Symbol: Lyar
Name: Ly1 antibody reactive
RGD ID: 18925317
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); identical protein binding (inferred); INVOLVED IN erythrocyte development (inferred); negative regulation of innate immune response (inferred); negative regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Ellis-Van Creveld syndrome (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cell growth-regulating nucleolar protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475521,434,144 - 21,450,124 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Lyar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475521,434,144 - 21,450,124 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LYAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3844,267,701 - 4,290,154 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl44,267,701 - 4,290,154 (-)EnsemblGRCh38hg38GRCh38
GRCh3744,269,428 - 4,291,881 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3644,320,337 - 4,342,744 (-)NCBINCBI36Build 36hg18NCBI36
Celera44,167,051 - 4,189,521 (-)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef44,205,115 - 4,227,579 (-)NCBIHuRef
CHM1_144,267,309 - 4,289,782 (-)NCBICHM1_1
T2T-CHM13v2.044,237,159 - 4,259,618 (-)NCBIT2T-CHM13v2.0
Lyar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39538,377,815 - 38,391,650 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl538,377,814 - 38,391,650 (+)EnsemblGRCm39 Ensembl
GRCm38538,220,471 - 38,234,306 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl538,220,470 - 38,234,306 (+)EnsemblGRCm38mm10GRCm38
MGSCv37538,611,721 - 38,625,545 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36538,508,799 - 38,522,546 (+)NCBIMGSCv36mm8
Celera535,670,252 - 35,684,076 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.29NCBI
Lyar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81476,789,193 - 76,802,973 (-)NCBIGRCr8
mRatBN7.21472,576,878 - 72,590,854 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1472,576,879 - 72,590,612 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1477,018,568 - 77,032,136 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01478,259,442 - 78,273,010 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01474,699,518 - 74,713,086 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01477,308,211 - 77,321,931 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1477,308,204 - 77,321,977 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01477,290,073 - 77,303,793 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41477,859,637 - 77,873,205 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11477,862,030 - 77,875,596 (-)NCBI
Celera1471,527,386 - 71,540,966 (-)NCBICelera
Cytogenetic Map14q21NCBI
Lyar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555145,358,843 - 5,376,112 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555145,358,843 - 5,375,990 (+)NCBIChiLan1.0ChiLan1.0
LYAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v234,534,513 - 4,557,030 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan144,467,357 - 4,489,984 (-)NCBINHGRI_mPanPan1
PanPan1.144,348,263 - 4,370,716 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl44,348,263 - 4,364,347 (-)Ensemblpanpan1.1panPan2
LYAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1369,710,735 - 69,724,175 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl369,710,735 - 69,724,177 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha372,262,732 - 72,281,663 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0370,467,687 - 70,486,622 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl370,467,692 - 70,486,574 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1369,741,785 - 69,760,718 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0369,906,935 - 69,925,842 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0370,288,339 - 70,307,278 (-)NCBIUU_Cfam_GSD_1.0
Lyar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528563,232,715 - 63,257,046 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647716,934,401 - 16,958,722 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl86,081,368 - 6,099,857 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.186,081,332 - 6,099,861 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.285,776,295 - 5,794,805 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LYAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12740,410,849 - 40,433,942 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604787,211,025 - 87,233,986 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004847296   ⟹   XP_004847353
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475521,434,144 - 21,450,096 (-)NCBI
RefSeq Acc Id: XM_004847297   ⟹   XP_004847354
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475521,434,144 - 21,450,124 (-)NCBI
RefSeq Acc Id: XM_013073144   ⟹   XP_012928598
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475521,434,144 - 21,450,096 (-)NCBI
RefSeq Acc Id: XM_021260298   ⟹   XP_021115957
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475521,434,144 - 21,449,769 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004847353 (Get FASTA)   NCBI Sequence Viewer  
  XP_004847354 (Get FASTA)   NCBI Sequence Viewer  
  XP_012928598 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115957 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB03652 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000044447
  ENSHGLP00100032324
GenBank Protein JAO02241 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004847354   ⟸   XM_004847297
- Peptide Label: isoform X1
- UniProtKB: G5B2Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012928598   ⟸   XM_013073144
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004847353   ⟸   XM_004847296
- Peptide Label: isoform X1
- UniProtKB: G5B2Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021115957   ⟸   XM_021260298
- Peptide Label: isoform X1
- UniProtKB: G5B2Z1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000039937 UniProtKB/TrEMBL
  ENSHGLG00100048298 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000087078 UniProtKB/TrEMBL
  ENSHGLT00100093259 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2100 UniProtKB/TrEMBL
  3.30.1490.490 UniProtKB/TrEMBL
InterPro LYAR UniProtKB/TrEMBL
  Znf-ACC UniProtKB/TrEMBL
  Znf_C2H2_LYAR UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report hgl:101704670 UniProtKB/TrEMBL
NCBI Gene Lyar ENTREZGENE
PANTHER CELL GROWTH-REGULATING NUCLEOLAR PROTEIN UniProtKB/TrEMBL
  PTHR13100 UniProtKB/TrEMBL
Pfam zf-ACC UniProtKB/TrEMBL
  zf-LYAR UniProtKB/TrEMBL
PROSITE ZF_C2HC_LYAR UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt G5B2Z1 ENTREZGENE, UniProtKB/TrEMBL