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Gene: LYAR (Ly1 antibody reactive) Homo sapiens
Symbol: LYAR
Name: Ly1 antibody reactive
Description: Exhibits DNA binding activity and identical protein binding activity. Involved in erythrocyte development; negative regulation of transcription by RNA polymerase II; and rRNA processing. Localizes to nucleolus and nucleoplasm; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cell growth-regulating nucleolar protein; FLJ20425; Ly1 antibody reactive homolog; ZC2HC2; ZLYAR
Mus musculus (house mouse) : Lyar (Ly1 antibody reactive clone)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lyar (Ly1 antibody reactive)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lyar (Ly1 antibody reactive)
Pan paniscus (bonobo/pygmy chimpanzee) : LYAR (Ly1 antibody reactive)
Canis lupus familiaris (dog) : LYAR (Ly1 antibody reactive)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lyar (Ly1 antibody reactive)
Sus scrofa (pig) : LYAR (Ly1 antibody reactive)
Chlorocebus sabaeus (African green monkey) : LYAR (Ly1 antibody reactive)
Heterocephalus glaber (naked mole-rat) : Lyar (Ly1 antibody reactive)
more info ...
Related Pseudogenes: LYARP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl44,267,701 - 4,290,154 (-)EnsemblGRCh38hg38GRCh38
GRCh3844,267,701 - 4,290,195 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3744,269,428 - 4,291,896 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3644,320,337 - 4,342,744 (-)NCBINCBI36hg18NCBI36
Celera44,167,051 - 4,189,521 (-)NCBI
Cytogenetic Map4p16.3NCBI
HuRef44,205,115 - 4,227,579 (-)NCBIHuRef
CHM1_144,267,309 - 4,289,782 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LYAR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604346
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.