Cpb1 (carboxypeptidase B1) - Rat Genome Database

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Gene: Cpb1 (carboxypeptidase B1) Heterocephalus glaber
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Symbol: Cpb1
Name: carboxypeptidase B1
RGD ID: 18925265
Description: ENCODES a protein that exhibits carboxypeptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH aceruloplasminemia (ortholog); glycogen storage disease XV (ortholog); FOUND IN cytoplasmic vesicle (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: carboxypeptidase B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473026,059,150 - 26,092,486 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473026,059,326 - 26,092,556 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA,ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cpb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473026,059,150 - 26,092,486 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473026,059,326 - 26,092,556 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CPB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383148,827,811 - 148,860,187 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3148,791,102 - 148,860,187 (+)EnsemblGRCh38hg38GRCh38
GRCh373148,545,598 - 148,577,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363150,028,278 - 150,060,664 (+)NCBINCBI36Build 36hg18NCBI36
Build 343150,028,285 - 150,060,668NCBI
Celera3146,955,960 - 146,988,049 (+)NCBICelera
Cytogenetic Map3q24NCBI
HuRef3145,918,017 - 145,950,076 (+)NCBIHuRef
CHM1_13148,508,723 - 148,540,807 (+)NCBICHM1_1
T2T-CHM13v2.03151,578,867 - 151,610,937 (+)NCBIT2T-CHM13v2.0
Cpb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39320,303,643 - 20,339,681 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl320,302,428 - 20,329,897 (-)EnsemblGRCm39 Ensembl
GRCm38320,249,479 - 20,275,733 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl320,248,264 - 20,275,733 (-)EnsemblGRCm38mm10GRCm38
MGSCv37320,149,383 - 20,174,651 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36320,441,534 - 20,466,802 (-)NCBIMGSCv36mm8
Celera320,238,683 - 20,264,826 (-)NCBICelera
Cytogenetic Map3A2NCBI
cM Map36.29NCBI
Cpb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82104,684,275 - 104,744,824 (-)NCBIGRCr8
mRatBN7.22102,755,241 - 102,785,628 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2102,755,241 - 102,785,628 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2109,302,257 - 109,332,662 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02107,423,440 - 107,453,849 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02102,350,160 - 102,384,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02105,059,293 - 105,089,682 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2105,059,426 - 105,089,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02124,787,804 - 124,850,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,413,336 - 105,443,909 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12105,358,297 - 105,388,871 (-)NCBI
Celera298,123,613 - 98,155,223 (-)NCBICelera
Cytogenetic Map2q24NCBI
Cpb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554748,632,228 - 8,697,245 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554748,632,733 - 8,697,197 (-)NCBIChiLan1.0ChiLan1.0
CPB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,687,228 - 146,756,143 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13146,691,965 - 146,760,873 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03145,815,651 - 145,884,498 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13153,431,094 - 153,463,177 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3153,394,339 - 153,463,366 (+)Ensemblpanpan1.1panPan2
CPB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12343,679,901 - 43,714,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2343,679,361 - 43,748,213 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2343,544,341 - 43,578,459 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02344,307,489 - 44,341,627 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2344,276,898 - 44,375,642 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12343,889,898 - 43,924,027 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02343,943,078 - 43,978,590 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02344,198,385 - 44,232,509 (+)NCBIUU_Cfam_GSD_1.0
Cpb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560282,972,757 - 83,009,199 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365196,724,836 - 6,755,610 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365196,724,836 - 6,755,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1389,044,310 - 89,088,392 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11389,043,822 - 89,088,387 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21397,005,130 - 97,030,476 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11541,845,115 - 41,877,173 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1541,845,115 - 41,877,377 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604114,687,765 - 14,719,995 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000016787   ⟹   ENSHGLP00000016617
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473026,059,150 - 26,092,486 (+)Ensembl
RefSeq Acc Id: XM_021259311   ⟹   XP_021114970
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473026,059,326 - 26,092,556 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021114970 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021114970   ⟸   XM_021259311
- UniProtKB: G5BSK3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000016617   ⟸   ENSHGLT00000016787


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011884 Ensembl
Gene3D-CATH Metallocarboxypeptidase-like UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CPB_M14_CPD UniProtKB/TrEMBL
  M14A-like_propep UniProtKB/TrEMBL
  M14A_act_pep UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene Cpb1 ENTREZGENE
PANTHER CARBOXYPEPTIDASE B UniProtKB/TrEMBL
  PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B UniProtKB/TrEMBL
Pfam Peptidase_M14 UniProtKB/TrEMBL
  Propep_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
SMART Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP Protease propeptides/inhibitors UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt G5BSK3 ENTREZGENE, UniProtKB/TrEMBL