Pla2g7 (phospholipase A2 group VII) - Rat Genome Database

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Gene: Pla2g7 (phospholipase A2 group VII) Heterocephalus glaber
Analyze
Symbol: Pla2g7
Name: phospholipase A2 group VII
RGD ID: 18921796
Description: ENCODES a protein that exhibits calcium-independent phospholipase A2 activity (ortholog); phospholipid binding (ortholog); INVOLVED IN lipid oxidation (ortholog); low-density lipoprotein particle remodeling (ortholog); phosphatidylcholine catabolic process (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Coronary Syndrome (ortholog); asthma (ortholog); FOUND IN extracellular space (ortholog); high-density lipoprotein particle (ortholog); low-density lipoprotein particle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Platelet-activating factor acetylhydrolase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475413,904,797 - 13,931,670 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475413,905,084 - 13,932,366 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pla2g7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475413,904,797 - 13,931,670 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475413,905,084 - 13,932,366 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLA2G7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,704,201 - 46,735,721 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,704,201 - 46,735,693 (-)EnsemblGRCh38hg38GRCh38
GRCh37646,671,938 - 46,703,458 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,780,237 - 46,811,061 (-)NCBINCBI36Build 36hg18NCBI36
Build 34646,780,236 - 46,811,055NCBI
Celera648,224,575 - 48,255,899 (-)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef646,395,325 - 46,426,641 (-)NCBIHuRef
CHM1_1646,675,466 - 46,706,812 (-)NCBICHM1_1
T2T-CHM13v2.0646,541,848 - 46,573,478 (-)NCBIT2T-CHM13v2.0
Pla2g7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,879,009 - 43,923,093 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,878,989 - 43,923,092 (+)EnsemblGRCm39 Ensembl
GRCm381743,567,994 - 43,612,202 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,568,098 - 43,612,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv371743,705,400 - 43,749,150 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,031,500 - 43,075,242 (+)NCBIMGSCv36mm8
Celera1746,991,155 - 47,035,006 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.74NCBI
Pla2g7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,859,491 - 24,901,747 (-)NCBIGRCr8
mRatBN7.2917,362,214 - 17,404,476 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,362,225 - 17,404,476 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,952,093 - 25,994,494 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0931,026,641 - 31,069,054 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,315,869 - 29,358,274 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,935,754 - 19,978,013 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,935,768 - 19,978,013 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,813,216 - 18,855,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,057,988 - 13,100,289 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,055,311 - 13,097,611 (-)NCBI
Celera915,085,734 - 15,127,419 (-)NCBICelera
Cytogenetic Map9q13NCBI
Pla2g7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,534,173 - 11,555,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,534,251 - 11,577,942 (-)NCBIChiLan1.0ChiLan1.0
PLA2G7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2561,165,585 - 61,231,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1657,031,715 - 57,097,254 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0646,264,262 - 46,318,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,558,861 - 47,590,212 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,558,861 - 47,590,212 (-)Ensemblpanpan1.1panPan2
PLA2G7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,866,229 - 14,908,230 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,866,229 - 14,908,114 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,897,517 - 14,938,972 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01215,366,067 - 15,408,199 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1215,366,063 - 15,408,686 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,881,621 - 14,922,982 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,970,576 - 15,012,067 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,117,009 - 15,158,322 (-)NCBIUU_Cfam_GSD_1.0
Pla2g7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,314,028 - 50,350,357 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647613,609,374 - 13,649,998 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647613,609,847 - 13,646,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl741,486,598 - 41,531,345 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1741,488,152 - 41,531,383 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,149,037 - 48,192,545 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,538,645 - 25,571,230 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1725,538,438 - 25,574,269 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,721,234 - 46,754,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027558   ⟹   ENSHGLP00000027316
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475413,904,797 - 13,931,670 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000027559   ⟹   ENSHGLP00000027317
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475413,910,492 - 13,931,670 (+)Ensembl
RefSeq Acc Id: XM_004846411   ⟹   XP_004846468
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475413,905,084 - 13,932,366 (+)NCBI
RefSeq Acc Id: XM_021259711   ⟹   XP_021115370
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475413,911,187 - 13,932,366 (+)NCBI
RefSeq Acc Id: XM_021259712   ⟹   XP_021115371
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475413,911,205 - 13,932,366 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846468 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115370 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115371 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10901 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027316
  ENSHGLP00000027317
GenBank Protein JAO00580 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004846468   ⟸   XM_004846411
- UniProtKB: A0A0P6JA81 (UniProtKB/TrEMBL),   G5BNG0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021115370   ⟸   XM_021259711
- UniProtKB: A0A0P6JA81 (UniProtKB/TrEMBL),   G5BNG0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021115371   ⟸   XM_021259712
- UniProtKB: A0A0P6JA81 (UniProtKB/TrEMBL),   G5BNG0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000027317   ⟸   ENSHGLT00000027559
Ensembl Acc Id: ENSHGLP00000027316   ⟸   ENSHGLT00000027558


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019421 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027558 ENTREZGENE
  ENSHGLT00000027559 ENTREZGENE
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  PAF_acetylhydro_eucaryote UniProtKB/TrEMBL
KEGG Report hgl:101716824 UniProtKB/TrEMBL
NCBI Gene Pla2g7 ENTREZGENE
PANTHER PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE UniProtKB/TrEMBL
  PTHR10272 UniProtKB/TrEMBL
Pfam PAF-AH_p_II UniProtKB/TrEMBL
PIRSF PAF_acetylhydrolase UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A0P6JA81 ENTREZGENE, UniProtKB/TrEMBL
  G5BNG0 ENTREZGENE, UniProtKB/TrEMBL