Efemp1 (EGF containing fibulin extracellular matrix protein 1) - Rat Genome Database

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Gene: Efemp1 (EGF containing fibulin extracellular matrix protein 1) Heterocephalus glaber
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Symbol: Efemp1
Name: EGF containing fibulin extracellular matrix protein 1
RGD ID: 18917840
Description: ENCODES a protein that exhibits calcium ion binding (inferred); epidermal growth factor receptor activity (inferred); epidermal growth factor receptor binding (inferred); INVOLVED IN negative regulation of neuron projection development (ortholog); peptidyl-tyrosine phosphorylation (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); adenoma (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN basement membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EGF containing fibulin like extracellular matrix protein 1; EGF-containing fibulin-like extracellular matrix protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248335,654,016 - 5,723,519 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248335,654,805 - 5,722,185 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Efemp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248335,654,016 - 5,723,519 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248335,654,805 - 5,722,185 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EFEMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38255,865,967 - 55,923,782 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl255,865,967 - 55,924,139 (-)EnsemblGRCh38hg38GRCh38
GRCh37256,093,102 - 56,150,917 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36255,946,606 - 56,004,436 (-)NCBINCBI36Build 36hg18NCBI36
Build 34256,004,748 - 56,060,856NCBI
Celera255,933,455 - 55,991,286 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,828,195 - 55,886,081 (-)NCBIHuRef
CHM1_1256,023,033 - 56,081,234 (-)NCBICHM1_1
T2T-CHM13v2.0255,862,877 - 55,920,674 (-)NCBIT2T-CHM13v2.0
Efemp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,803,154 - 28,876,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1128,803,204 - 28,876,743 (+)EnsemblGRCm39 Ensembl
GRCm381128,853,154 - 28,926,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,853,204 - 28,926,743 (+)EnsemblGRCm38mm10GRCm38
MGSCv371128,753,205 - 28,826,743 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361128,767,773 - 28,826,737 (+)NCBIMGSCv36mm8
Celera1131,227,166 - 31,304,265 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.32NCBI
Efemp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814106,811,769 - 106,890,961 (+)NCBIGRCr8
mRatBN7.214102,610,813 - 102,690,027 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,610,908 - 102,690,018 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14106,946,350 - 107,025,480 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,182,972 - 108,262,217 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,655,396 - 104,734,632 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,202,382 - 113,294,993 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,202,419 - 113,295,014 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014112,892,387 - 112,902,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.014112,961,348 - 112,984,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414109,733,625 - 109,828,630 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114109,759,971 - 109,854,973 (+)NCBI
Celera14101,510,577 - 101,587,921 (+)NCBICelera
Cytogenetic Map14q22NCBI
Efemp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542427,181,099 - 27,240,446 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542427,181,717 - 27,240,067 (+)NCBIChiLan1.0ChiLan1.0
EFEMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21270,407,006 - 70,464,773 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A70,410,928 - 70,468,816 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A56,017,678 - 56,076,059 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A57,155,000 - 57,212,500 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A57,155,000 - 57,212,500 (-)Ensemblpanpan1.1panPan2
EFEMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,632,801 - 56,694,872 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1056,579,899 - 56,787,187 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1056,589,822 - 56,651,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01057,637,641 - 57,699,724 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1057,637,642 - 57,699,051 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11057,338,037 - 57,400,109 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,617,689 - 57,679,576 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01057,909,175 - 57,970,591 (-)NCBIUU_Cfam_GSD_1.0
Efemp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629226,356,792 - 26,411,638 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364912,159,096 - 2,214,677 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364912,159,654 - 2,214,480 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFEMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl385,407,677 - 85,473,252 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1385,407,677 - 85,473,251 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,132,118 - 90,197,711 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFEMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11450,989,553 - 51,048,149 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1450,989,795 - 51,048,708 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604560,671,542 - 60,729,463 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000010084   ⟹   ENSHGLP00000009973
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248335,654,016 - 5,723,519 (+)Ensembl
RefSeq Acc Id: XM_004867256   ⟹   XP_004867313
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248335,654,805 - 5,722,185 (+)NCBI
RefSeq Acc Id: XM_021246278   ⟹   XP_021101937
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248335,654,972 - 5,721,734 (+)NCBI
RefSeq Acc Id: XM_021246279   ⟹   XP_021101938
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248335,655,220 - 5,721,734 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004867313 (Get FASTA)   NCBI Sequence Viewer  
  XP_021101937 (Get FASTA)   NCBI Sequence Viewer  
  XP_021101938 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000009973
  ENSHGLP00100036477
GenBank Protein JAO01892 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004867313   ⟸   XM_004867256
- UniProtKB: A0A0P6JGB6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101937   ⟸   XM_021246278
- UniProtKB: A0A0P6JGB6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101938   ⟸   XM_021246279
- UniProtKB: A0A0P6JGB6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000009973   ⟸   ENSHGLT00000010084


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007156 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100016272 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000010084 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100078782 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  ECM_structural_protein UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
NCBI Gene Efemp1 ENTREZGENE
PANTHER EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 UniProtKB/TrEMBL
  EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  Fibulin_C UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
UniProt A0A0P6JGB6 ENTREZGENE, UniProtKB/TrEMBL