Cd109 (CD109 molecule) - Rat Genome Database

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Gene: Cd109 (CD109 molecule) Heterocephalus glaber
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Symbol: Cd109
Name: CD109 molecule
RGD ID: 18915953
Description: ENCODES a protein that exhibits endopeptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN hair follicle development (ortholog); keratinocyte proliferation (ortholog); negative regulation of keratinocyte proliferation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); High Myopia (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD109 antigen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624819862,194 - 1,009,755 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624819861,095 - 1,013,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cd109
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624819862,194 - 1,009,755 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624819861,095 - 1,013,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CD109
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38673,679,192 - 73,828,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl673,695,785 - 73,828,316 (+)EnsemblGRCh38hg38GRCh38
GRCh37674,405,926 - 74,538,037 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36674,462,235 - 74,594,761 (+)NCBINCBI36Build 36hg18NCBI36
Build 34674,462,547 - 74,591,509NCBI
Celera674,800,739 - 74,932,977 (+)NCBICelera
Cytogenetic Map6q13NCBI
HuRef671,605,012 - 71,737,517 (+)NCBIHuRef
CHM1_1674,571,928 - 74,704,279 (+)NCBICHM1_1
T2T-CHM13v2.0674,857,189 - 75,006,336 (+)NCBIT2T-CHM13v2.0
Cd109
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39978,522,828 - 78,623,542 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl978,522,828 - 78,623,535 (+)EnsemblGRCm39 Ensembl
GRCm38978,615,546 - 78,716,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,615,546 - 78,716,253 (+)EnsemblGRCm38mm10GRCm38
MGSCv37978,463,353 - 78,564,067 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36978,401,461 - 78,501,937 (+)NCBIMGSCv36mm8
Celera975,790,926 - 75,891,369 (+)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.65NCBI
Cd109
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8888,334,736 - 88,449,463 (+)NCBIGRCr8
mRatBN7.2879,454,480 - 79,569,195 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl879,454,480 - 79,569,194 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,984,275 - 85,092,412 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0883,261,419 - 83,369,553 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0881,084,098 - 81,192,223 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,951,420 - 86,065,411 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,951,191 - 86,065,409 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,500,667 - 85,615,070 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,576,559 - 83,672,664 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1883,578,579 - 83,692,225 (+)NCBI
Celera879,200,276 - 79,310,457 (+)NCBICelera
Cytogenetic Map8q31NCBI
Cd109
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554889,281,661 - 9,378,490 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554889,281,407 - 9,378,354 (-)NCBIChiLan1.0ChiLan1.0
CD109
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2593,722,849 - 93,859,415 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1691,574,608 - 91,734,821 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0671,519,293 - 71,654,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1674,801,384 - 74,937,414 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl674,801,384 - 74,937,414 (+)Ensemblpanpan1.1panPan2
CD109
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11235,712,589 - 35,839,153 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1235,712,271 - 35,839,044 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1235,583,900 - 35,710,288 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01236,269,369 - 36,395,815 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1236,268,808 - 36,395,710 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11235,808,332 - 35,938,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01235,830,291 - 35,960,639 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01235,954,644 - 36,085,062 (+)NCBIUU_Cfam_GSD_1.0
Cd109
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494671,014,831 - 71,146,089 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936859484,923 - 595,316 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936859467,958 - 595,337 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD109
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl192,054,821 - 92,286,730 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1192,081,675 - 92,241,079 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21103,135,603 - 103,292,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD109
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,322,681 - 1,461,945 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl171,324,105 - 1,416,491 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660587,225,201 - 7,365,431 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000001262   ⟹   ENSHGLP00000001220
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624819862,194 - 1,009,755 (+)Ensembl
RefSeq Acc Id: XM_021243725   ⟹   XP_021099384
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624819861,095 - 1,013,674 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021099384 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001220
GenBank Protein JAO00491 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021099384   ⟸   XM_021243725
- UniProtKB: A0A0P6J8B7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000001220   ⟸   ENSHGLT00000001262


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000949 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001262 ENTREZGENE
Gene3D-CATH 1.50.10.20 UniProtKB/TrEMBL
  2.20.130.20 UniProtKB/TrEMBL
  2.60.120.1540 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  2.60.40.1930 UniProtKB/TrEMBL
  2.60.40.1940 UniProtKB/TrEMBL
  2.60.40.2950 UniProtKB/TrEMBL
  2.60.40.690 UniProtKB/TrEMBL
  6.20.50.160 UniProtKB/TrEMBL
InterPro A-macroglobulin_rcpt-bd UniProtKB/TrEMBL
  A-macroglobulin_rcpt-bd_sf UniProtKB/TrEMBL
  A2M/Complement_sys UniProtKB/TrEMBL
  A2M_N_BRD UniProtKB/TrEMBL
  A2M_TED UniProtKB/TrEMBL
  Alpha-macroglob_thiol-ester_cl UniProtKB/TrEMBL
  Alpha-macroglobulin_TED UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  Macroglobln_a2 UniProtKB/TrEMBL
  MacrogloblnA2_CS UniProtKB/TrEMBL
  MG2 UniProtKB/TrEMBL
  MG3 UniProtKB/TrEMBL
  Terpenoid_cyclase/PrenylTrfase UniProtKB/TrEMBL
NCBI Gene Cd109 ENTREZGENE
PANTHER CD109 ANTIGEN UniProtKB/TrEMBL
  MACROGLOBULIN / COMPLEMENT UniProtKB/TrEMBL
Pfam A2M UniProtKB/TrEMBL
  A2M_BRD UniProtKB/TrEMBL
  A2M_recep UniProtKB/TrEMBL
  MG2 UniProtKB/TrEMBL
  MG3 UniProtKB/TrEMBL
  TED_complement UniProtKB/TrEMBL
PROSITE ALPHA_2_MACROGLOBULIN UniProtKB/TrEMBL
SMART A2M UniProtKB/TrEMBL
  A2M_N_2 UniProtKB/TrEMBL
  A2M_recep UniProtKB/TrEMBL
  Thiol-ester_cl UniProtKB/TrEMBL
Superfamily-SCOP SSF48239 UniProtKB/TrEMBL
  SSF49410 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A0P6J8B7 ENTREZGENE, UniProtKB/TrEMBL