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Gene: CD109 (CD109 molecule) Homo sapiens
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Symbol: CD109
Name: CD109 molecule
Description: Exhibits transforming growth factor beta binding activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway and negative regulation of wound healing. Localizes to cytosol and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109 antigen; CPAMD7; DKFZp762L1111; FLJ38569; FLJ41966; Gov platelet alloantigens; p180; platelet-specific Gov antigen; r150; RP11-525G3.1
Orthologs:
Mus musculus (house mouse) : Cd109 (CD109 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd109 (CD109 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd109 (CD109 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD109 (CD109 molecule)
Canis lupus familiaris (dog) : CD109 (CD109 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd109 (CD109 molecule)
Sus scrofa (pig) : CD109 (CD109 molecule)
Chlorocebus sabaeus (African green monkey) : CD109 (CD109 molecule)
Heterocephalus glaber (naked mole-rat) : Cd109 (CD109 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl673,695,785 - 73,828,316 (+)EnsemblGRCh38hg38GRCh38
GRCh38673,696,085 - 73,828,317 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37674,405,508 - 74,538,041 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36674,462,235 - 74,594,761 (+)NCBINCBI36hg18NCBI36
Build 34674,462,547 - 74,591,509NCBI
Celera674,800,739 - 74,932,977 (+)NCBI
Cytogenetic Map6q13NCBI
HuRef671,605,012 - 71,737,517 (+)NCBIHuRef
CHM1_1674,572,228 - 74,704,279 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CD109
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322663
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.