Hs2st1 (heparan sulfate 2-O-sulfotransferase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Hs2st1 (heparan sulfate 2-O-sulfotransferase 1) Heterocephalus glaber
Analyze
Symbol: Hs2st1
Name: heparan sulfate 2-O-sulfotransferase 1
RGD ID: 18912144
Description: ENCODES a protein that exhibits heparan sulfate 2-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN gene expression (ortholog); heparan sulfate proteoglycan biosynthetic process (ortholog); heparan sulfate proteoglycan biosynthetic process, chain elongation (ortholog); ASSOCIATED WITH genetic disease (ortholog); NEUROFACIOSKELETAL SYNDROME WITH OR WITHOUT RENAL AGENESIS (ortholog); FOUND IN Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474210,475,748 - 10,695,525 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474210,472,607 - 10,695,939 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Golgi apparatus  (IEA,ISO)
Golgi membrane  (IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hs2st1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474210,475,748 - 10,695,525 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474210,472,607 - 10,695,939 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HS2ST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38186,914,635 - 87,109,982 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl186,914,635 - 87,109,982 (+)EnsemblGRCh38hg38GRCh38
GRCh37187,380,318 - 87,575,665 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36187,152,950 - 87,348,252 (+)NCBINCBI36Build 36hg18NCBI36
Build 34187,092,382 - 87,287,685NCBI
Celera185,623,706 - 85,821,380 (+)NCBICelera
Cytogenetic Map1p22.3NCBI
HuRef185,491,509 - 85,689,310 (+)NCBIHuRef
CHM1_1187,495,264 - 87,690,587 (+)NCBICHM1_1
T2T-CHM13v2.0186,755,193 - 86,952,707 (+)NCBIT2T-CHM13v2.0
Hs2st1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393144,135,462 - 144,275,977 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3144,135,467 - 144,275,942 (-)EnsemblGRCm39 Ensembl
GRCm383144,429,701 - 144,570,216 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3144,429,706 - 144,570,181 (-)EnsemblGRCm38mm10GRCm38
MGSCv373144,094,071 - 144,233,180 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363144,368,496 - 144,507,524 (-)NCBIMGSCv36mm8
Celera3150,868,350 - 150,902,535 (-)NCBICelera
Cytogenetic Map3H2NCBI
cM Map368.89NCBI
Hs2st1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82236,168,391 - 236,302,186 (-)NCBIGRCr8
mRatBN7.22233,508,018 - 233,641,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2233,508,021 - 233,641,769 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2241,293,616 - 241,427,487 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02239,187,993 - 239,321,667 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02234,051,219 - 234,185,095 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02250,467,428 - 250,600,517 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2250,467,429 - 250,600,517 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02268,996,210 - 269,129,114 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42242,622,270 - 242,760,095 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12242,610,982 - 242,746,835 (-)NCBI
Celera2225,501,220 - 225,634,734 (-)NCBICelera
Cytogenetic Map2q44NCBI
Hs2st1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554237,091,765 - 7,253,339 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554237,090,246 - 7,253,608 (-)NCBIChiLan1.0ChiLan1.0
HS2ST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21139,858,992 - 140,058,251 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11139,015,922 - 139,213,658 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,432,583 - 119,630,472 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1188,283,486 - 88,480,498 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl188,283,872 - 88,475,198 (+)Ensemblpanpan1.1panPan2
HS2ST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1661,124,393 - 61,298,912 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha663,838,125 - 64,012,670 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0661,664,708 - 61,838,267 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl661,666,849 - 61,838,280 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1661,198,888 - 61,372,107 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0661,155,168 - 61,335,473 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0661,660,387 - 61,834,150 (-)NCBIUU_Cfam_GSD_1.0
Hs2st1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505897,492,076 - 97,666,113 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367321,773,028 - 1,946,696 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367321,773,043 - 1,947,081 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HS2ST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4129,104,606 - 129,258,377 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14129,101,900 - 129,258,372 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24141,550,206 - 141,705,780 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HS2ST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12046,346,009 - 46,546,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2046,350,496 - 46,386,791 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603371,286,322 - 71,488,665 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012022   ⟹   ENSHGLP00000011892
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474210,475,748 - 10,695,525 (-)Ensembl
RefSeq Acc Id: XM_004841336   ⟹   XP_004841393
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474210,472,607 - 10,695,939 (-)NCBI
RefSeq Acc Id: XM_004841337   ⟹   XP_004841394
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474210,474,378 - 10,695,645 (-)NCBI
RefSeq Acc Id: XM_013070915   ⟹   XP_012926369
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474210,472,607 - 10,580,556 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004841393 (Get FASTA)   NCBI Sequence Viewer  
  XP_004841394 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926369 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011892
RefSeq Acc Id: XP_004841393   ⟸   XM_004841336
- Peptide Label: isoform X1
- UniProtKB: A0AAX6P108 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926369   ⟸   XM_013070915
- Peptide Label: isoform X3
- UniProtKB: A0AAX6QTM6 (UniProtKB/TrEMBL),   G5BGG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841394   ⟸   XM_004841337
- Peptide Label: isoform X2
- UniProtKB: A0AAX6P0X0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011892   ⟸   ENSHGLT00000012022


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008512 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000012022 ENTREZGENE
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
InterPro Heparan_SO4_2-O-STrfase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase UniProtKB/TrEMBL
NCBI Gene Hs2st1 ENTREZGENE
PANTHER HEPARAN SULFATE 2-O-SULFOTRANSFERASE UniProtKB/TrEMBL
  HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 UniProtKB/TrEMBL
Pfam Sulfotransfer_2 UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt A0AAX6P0X0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6P108 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QTM6 ENTREZGENE, UniProtKB/TrEMBL
  G5BGG3 ENTREZGENE, UniProtKB/TrEMBL