HS2ST1 (heparan sulfate 2-O-sulfotransferase 1) - Rat Genome Database

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Gene: HS2ST1 (heparan sulfate 2-O-sulfotransferase 1) Sus scrofa
Analyze
Symbol: HS2ST1
Name: heparan sulfate 2-O-sulfotransferase 1
RGD ID: 14239220
Description: INVOLVED IN gene expression (ortholog); heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process (ortholog); heparin metabolic process (ortholog); ASSOCIATED WITH NEUROFACIOSKELETAL SYNDROME WITH OR WITHOUT RENAL AGENESIS (ortholog); FOUND IN Golgi membrane (inferred); integral component of membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14129,101,900 - 129,258,372 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24141,550,206 - 141,705,780 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
HS2ST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14129,101,900 - 129,258,372 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24141,550,206 - 141,705,780 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HS2ST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl186,914,635 - 87,109,982 (+)EnsemblGRCh38hg38GRCh38
GRCh38186,914,635 - 87,109,982 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37187,380,318 - 87,575,665 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36187,152,950 - 87,348,252 (+)NCBINCBI36hg18NCBI36
Build 34187,092,382 - 87,287,685NCBI
Celera185,623,706 - 85,821,380 (+)NCBI
Cytogenetic Map1p22.3NCBI
HuRef185,491,509 - 85,689,310 (+)NCBIHuRef
CHM1_1187,495,264 - 87,690,587 (+)NCBICHM1_1
Hs2st1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393144,135,462 - 144,275,977 (-)NCBIGRCm39mm39
GRCm39 Ensembl3144,135,467 - 144,275,942 (-)Ensembl
GRCm383144,429,701 - 144,570,216 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3144,429,706 - 144,570,181 (-)EnsemblGRCm38mm10GRCm38
MGSCv373144,094,071 - 144,233,180 (-)NCBIGRCm37mm9NCBIm37
MGSCv363144,368,496 - 144,507,524 (-)NCBImm8
Celera3150,868,350 - 150,902,535 (-)NCBICelera
Cytogenetic Map3H2NCBI
Hs2st1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22233,508,018 - 233,641,769 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2233,508,021 - 233,641,769 (-)Ensembl
Rnor_6.02250,467,428 - 250,600,517 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2250,467,429 - 250,600,517 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02268,996,210 - 269,129,114 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42242,622,270 - 242,760,095 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12242,610,982 - 242,746,835 (-)NCBI
Celera2225,501,220 - 225,634,734 (-)NCBICelera
Cytogenetic Map2q44NCBI
Hs2st1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554237,090,246 - 7,253,608 (-)NCBIChiLan1.0ChiLan1.0
HS2ST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1188,283,486 - 88,480,498 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl188,283,872 - 88,475,198 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01119,432,583 - 119,630,472 (+)NCBIMhudiblu_PPA_v0panPan3
HS2ST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1661,124,393 - 61,298,912 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha663,838,125 - 64,012,670 (-)NCBI
ROS_Cfam_1.0661,664,708 - 61,838,267 (-)NCBI
UMICH_Zoey_3.1661,198,888 - 61,372,107 (-)NCBI
UNSW_CanFamBas_1.0661,155,168 - 61,335,473 (-)NCBI
UU_Cfam_GSD_1.0661,660,387 - 61,834,150 (-)NCBI
Hs2st1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505897,492,076 - 97,666,113 (+)NCBI
SpeTri2.0NW_0049367321,773,043 - 1,947,081 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HS2ST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12046,346,009 - 46,546,363 (-)NCBI
ChlSab1.1 Ensembl2046,350,496 - 46,386,791 (-)Ensembl
Vero_WHO_p1.0NW_02366603371,286,322 - 71,488,665 (+)NCBI
Hs2st1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474210,472,607 - 10,695,939 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 4 2
Low 10 4 3 5 2 19 2 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_001925492   ⟹   XP_001925527
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14129,101,900 - 129,258,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013997435   ⟹   XP_013852889
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14129,101,900 - 129,170,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013997436   ⟹   XP_013852890
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14129,101,900 - 129,174,572 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001925527 (Get FASTA)   NCBI Sequence Viewer  
  XP_013852889 (Get FASTA)   NCBI Sequence Viewer  
  XP_013852890 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_001925527   ⟸   XM_001925492
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013852890   ⟸   XM_013997436
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013852889   ⟸   XM_013997435
- Peptide Label: isoform X2
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000022032 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070015940 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000041470 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070026102 UniProtKB/TrEMBL
  ENSSSCP00070026116 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000058223 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070031311 UniProtKB/TrEMBL
  ENSSSCT00070031330 UniProtKB/TrEMBL
InterPro Heparan_SO4_2-O-STrfase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase UniProtKB/TrEMBL
NCBI Gene HS2ST1 ENTREZGENE
PANTHER PTHR12129 UniProtKB/TrEMBL
Pfam Sulfotransfer_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287AC51_PIG UniProtKB/TrEMBL
  A0A4X1UDF4_PIG UniProtKB/TrEMBL
  A0A4X1UDZ6_PIG UniProtKB/TrEMBL