Nr2c2 (nuclear receptor subfamily 2 group C member 2) - Rat Genome Database

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Gene: Nr2c2 (nuclear receptor subfamily 2 group C member 2) Heterocephalus glaber
Analyze
Symbol: Nr2c2
Name: nuclear receptor subfamily 2 group C member 2
RGD ID: 18911274
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cerebellum development (ortholog); lipopolysaccharide-mediated signaling pathway (ortholog); meiotic cell cycle (ortholog); ASSOCIATED WITH 3p deletion syndrome (ortholog); endometriosis (ortholog); Isolated Noncompaction of the Ventricular Myocardium (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624872953,097 - 981,974 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624872953,428 - 1,028,738 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nr2c2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624872953,097 - 981,974 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624872953,428 - 1,028,738 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NR2C2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38314,947,583 - 15,049,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl314,947,583 - 15,053,600 (+)EnsemblGRCh38hg38GRCh38
GRCh37314,989,090 - 15,090,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36314,964,240 - 15,065,784 (+)NCBINCBI36Build 36hg18NCBI36
Build 34314,964,239 - 15,059,854NCBI
Celera314,927,498 - 15,029,051 (+)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef314,980,982 - 15,026,388 (+)NCBIHuRef
CHM1_1314,940,196 - 15,041,731 (+)NCBICHM1_1
T2T-CHM13v2.0314,950,033 - 15,051,696 (+)NCBIT2T-CHM13v2.0
Nr2c2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39692,068,426 - 92,150,039 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl692,068,371 - 92,151,275 (+)EnsemblGRCm39 Ensembl
GRCm38692,091,418 - 92,173,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl692,091,390 - 92,174,294 (+)EnsemblGRCm38mm10GRCm38
MGSCv37692,041,412 - 92,123,052 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36692,104,498 - 92,133,463 (+)NCBIMGSCv36mm8
Celera693,985,636 - 94,068,601 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map641.03NCBI
Nr2c2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84126,167,350 - 126,223,942 (+)NCBIGRCr8
mRatBN7.24124,610,216 - 124,666,813 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,608,960 - 124,661,902 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4130,104,022 - 130,134,622 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04125,878,455 - 125,909,055 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,502,988 - 124,533,588 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04124,005,287 - 124,030,349 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4124,005,280 - 124,030,349 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04189,231,452 - 189,256,039 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,319,412 - 126,344,808 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,564,252 - 126,589,637 (+)NCBI
Celera4113,554,791 - 113,579,853 (+)NCBICelera
Cytogenetic Map4q34NCBI
Nr2c2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,386,190 - 17,430,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,386,190 - 17,430,820 (+)NCBIChiLan1.0ChiLan1.0
NR2C2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,928,971 - 15,033,524 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1314,933,922 - 15,040,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0314,869,292 - 14,973,977 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1315,220,110 - 15,312,507 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,220,110 - 15,306,242 (+)Ensemblpanpan1.1panPan2
NR2C2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1205,041,656 - 5,139,859 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl205,052,232 - 5,133,721 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha205,078,881 - 5,176,796 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0205,063,028 - 5,160,979 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl205,062,849 - 5,155,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1204,781,343 - 4,879,258 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0205,132,066 - 5,229,600 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0205,115,710 - 5,213,646 (+)NCBIUU_Cfam_GSD_1.0
Nr2c2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494218,355,583 - 18,417,842 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936602504,652 - 553,936 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936602491,821 - 557,790 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR2C2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1369,464,795 - 69,576,946 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11369,464,798 - 69,577,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21376,826,751 - 76,919,612 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NR2C2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12250,882,569 - 50,983,851 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2250,894,802 - 50,977,581 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041115,508,016 - 115,610,568 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000011044   ⟹   ENSHGLP00000010922
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624872953,097 - 981,974 (-)Ensembl
RefSeq Acc Id: XM_004870470   ⟹   XP_004870527
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872953,428 - 1,028,720 (-)NCBI
RefSeq Acc Id: XM_004870472   ⟹   XP_004870529
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872953,428 - 975,176 (-)NCBI
RefSeq Acc Id: XM_004870473   ⟹   XP_004870530
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872953,428 - 1,028,738 (-)NCBI
RefSeq Acc Id: XM_013067724   ⟹   XP_012923178
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872953,428 - 1,027,311 (-)NCBI
RefSeq Acc Id: XM_013067725   ⟹   XP_012923179
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872953,428 - 1,028,722 (-)NCBI
RefSeq Acc Id: XM_013067726   ⟹   XP_012923180
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872953,428 - 1,027,423 (-)NCBI
RefSeq Acc Id: XR_002391139
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624872957,888 - 1,027,318 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004870530   ⟸   XM_004870473
- Peptide Label: isoform X2
- UniProtKB: G5ANT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923179   ⟸   XM_013067725
- Peptide Label: isoform X2
- UniProtKB: G5ANT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004870527   ⟸   XM_004870470
- Peptide Label: isoform X2
- UniProtKB: G5ANT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923180   ⟸   XM_013067726
- Peptide Label: isoform X2
- UniProtKB: G5ANT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923178   ⟸   XM_013067724
- Peptide Label: isoform X1
- UniProtKB: G5ANT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004870529   ⟸   XM_004870472
- Peptide Label: isoform X2
- UniProtKB: G5ANT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000010922   ⟸   ENSHGLT00000011044


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007834 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011044 ENTREZGENE
Gene3D-CATH Erythroid Transcription Factor GATA-1, subunit A UniProtKB/TrEMBL
  Retinoid X Receptor UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/TrEMBL
  NR2C1/2-like_DBD UniProtKB/TrEMBL
  NR2C1/2-like_LBD UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
NCBI Gene Nr2c2 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/TrEMBL
  NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2 UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PRINTS STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  Nuclear receptor ligand-binding domain UniProtKB/TrEMBL
UniProt G5ANT1 ENTREZGENE, UniProtKB/TrEMBL