Symbol:
Aplp1
Name:
amyloid beta precursor like protein 1
RGD ID:
18908186
Description:
ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to norepinephrine stimulus (ortholog); cytosolic mRNA polyadenylation (ortholog); extracellular matrix organization (ortholog); ASSOCIATED WITH Brugada syndrome 5 (ortholog); hereditary spastic paraplegia 75 (ortholog); FOUND IN nucleoplasm (ortholog); perinuclear region of cytoplasm (ortholog)
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
amyloid beta (A4) precursor-like protein 1; amyloid-like protein 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Aplp1 (Heterocephalus glaber - naked mole-rat)
APLP1 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 35,868,574 - 35,879,792 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 35,867,899 - 35,879,803 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 36,359,476 - 36,370,694 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 41,051,241 - 41,062,539 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 41,051,309 - 41,062,530 NCBI Celera 19 33,073,585 - 33,084,883 (+) NCBI Celera Cytogenetic Map 19 q13.12 NCBI HuRef 19 32,864,721 - 32,875,938 (+) NCBI HuRef CHM1_1 19 36,360,683 - 36,371,980 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 38,414,328 - 38,425,546 (+) NCBI T2T-CHM13v2.0
Aplp1 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 30,134,405 - 30,144,960 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 30,134,407 - 30,144,960 (-) Ensembl GRCm39 Ensembl GRCm38 7 30,434,980 - 30,445,582 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 30,434,982 - 30,445,535 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 31,220,001 - 31,230,580 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 30,143,742 - 30,154,321 (-) NCBI MGSCv36 mm8 Celera 7 25,026,598 - 25,037,193 (-) NCBI Celera Cytogenetic Map 7 B1 NCBI cM Map 7 18.32 NCBI
Aplp1 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 94,824,330 - 94,834,705 (-) NCBI GRCr8 mRatBN7.2 1 85,696,880 - 85,707,215 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 85,696,882 - 85,707,155 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 91,113,388 - 91,123,714 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 99,579,915 - 99,590,199 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 92,871,656 - 92,881,982 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 88,897,525 - 88,908,750 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 88,897,532 - 88,908,750 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 90,053,390 - 90,063,110 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 85,390,217 - 85,401,952 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 1 80,069,348 - 80,079,276 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
Aplp1 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955468 2,694,591 - 2,703,656 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955468 2,694,286 - 2,703,658 (-) NCBI ChiLan1.0 ChiLan1.0
APLP1 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 41,867,959 - 41,879,251 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 43,852,723 - 43,864,012 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 19 32,786,362 - 32,797,728 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 41,534,776 - 41,545,908 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 19 41,534,569 - 41,545,906 (+) Ensembl panpan1.1 panPan2
APLP1 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 116,774,392 - 116,783,101 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 1 116,728,529 - 116,783,046 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 116,179,958 - 116,188,648 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 117,377,571 - 117,386,261 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 1 117,377,575 - 117,386,219 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 1 116,941,125 - 116,949,814 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 116,564,643 - 116,573,333 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 117,620,429 - 117,629,122 (-) NCBI UU_Cfam_GSD_1.0
Aplp1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
APLP1 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 45,285,718 - 45,295,350 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 45,285,698 - 45,295,355 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 40,669,837 - 40,672,028 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
APLP1 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 6 30,780,112 - 30,791,582 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 6 30,780,085 - 30,791,636 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666073 8,572,301 - 8,583,860 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
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Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSHGLT00000024193 ⟹ ENSHGLP00000023975
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla_female_1.0 Ensembl NW_004624794 10,148,522 - 10,167,543 (+) Ensembl
Ensembl Acc Id:
ENSHGLT00000024194 ⟹ ENSHGLP00000023976
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla_female_1.0 Ensembl NW_004624794 10,148,522 - 10,167,543 (+) Ensembl
Ensembl Acc Id:
ENSHGLT00000024195 ⟹ ENSHGLP00000023977
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla_female_1.0 Ensembl NW_004624794 10,148,642 - 10,167,135 (+) Ensembl
RefSeq Acc Id:
XM_004858949 ⟹ XP_004859006
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,588 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_004858950 ⟹ XP_004859007
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,590 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_013077414 ⟹ XP_012932868
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,581 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_013077415 ⟹ XP_012932869
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,583 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_013077416 ⟹ XP_012932870
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,578 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_013077417 ⟹ XP_012932871
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,582 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_021239454 ⟹ XP_021095113
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,575 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_021239455 ⟹ XP_021095114
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,579 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XM_021239456 ⟹ XP_021095115
Type:
CODING
Position:
Naked Mole-Rat Assembly Chr Position (strand) Source HetGla 1.0 NW_004624794 10,148,578 - 10,158,101 (+) NCBI
RefSeq Acc Id:
XP_021095113 ⟸ XM_021239454
- Peptide Label:
isoform X2
- UniProtKB:
A0AAX6RGZ4 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_012932870 ⟸ XM_013077416
- Peptide Label:
isoform X4
- UniProtKB:
A0AAX6R2A7 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_021095115 ⟸ XM_021239456
- Peptide Label:
isoform X8
- UniProtKB:
A0AAX6RD67 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_021095114 ⟸ XM_021239455
- Peptide Label:
isoform X5
- UniProtKB:
A0AAX6RGM8 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_012932868 ⟸ XM_013077414
- Peptide Label:
isoform X1
- UniProtKB:
A0AAX6R416 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_012932871 ⟸ XM_013077417
- Peptide Label:
isoform X6
- UniProtKB:
A0AAX6R5I0 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_012932869 ⟸ XM_013077415
- Peptide Label:
isoform X3
- UniProtKB:
A0AAX6R569 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_004859006 ⟸ XM_004858949
- Peptide Label:
isoform X7
- UniProtKB:
A0AAX6PSS7 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_004859007 ⟸ XM_004858950
- Peptide Label:
isoform X9
- UniProtKB:
A0AAX6PU42 (UniProtKB/TrEMBL), G5BXP2 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSHGLP00000023977 ⟸ ENSHGLT00000024195
Ensembl Acc Id:
ENSHGLP00000023976 ⟸ ENSHGLT00000024194
Ensembl Acc Id:
ENSHGLP00000023975 ⟸ ENSHGLT00000024193
Ensembl Genes
ENSHGLG00000017091
Ensembl
Gene3D-CATH
Amyloid precursor protein, E2 domain
UniProtKB/TrEMBL
Amyloidogenic glycoprotein, copper-binding domain
UniProtKB/TrEMBL
Amyloidogenic glycoprotein, heparin-binding domain
UniProtKB/TrEMBL
InterPro
Amyloid_Cu-bd_sf
UniProtKB/TrEMBL
Amyloid_glyco
UniProtKB/TrEMBL
Amyloid_glyco_Cu-bd
UniProtKB/TrEMBL
Amyloid_glyco_E2_domain
UniProtKB/TrEMBL
Amyloid_glyco_extra
UniProtKB/TrEMBL
Amyloid_glyco_heparin-bd
UniProtKB/TrEMBL
Amyloid_glyco_heparin-bd_sf
UniProtKB/TrEMBL
Amyloid_glyco_intracell_CS
UniProtKB/TrEMBL
APP_amyloid_C
UniProtKB/TrEMBL
APP_CUBD_CS
UniProtKB/TrEMBL
E2_sf
UniProtKB/TrEMBL
NCBI Gene
Aplp1
ENTREZGENE
PANTHER
ALZHEIMER'S DISEASE BETA-AMYLOID RELATED
UniProtKB/TrEMBL
AMYLOID-LIKE PROTEIN 1
UniProtKB/TrEMBL
Pfam
APP_amyloid
UniProtKB/TrEMBL
APP_Cu_bd
UniProtKB/TrEMBL
APP_E2
UniProtKB/TrEMBL
APP_N
UniProtKB/TrEMBL
PRINTS
AMYLOIDA4
UniProtKB/TrEMBL
PROSITE
APP_CUBD
UniProtKB/TrEMBL
APP_E1
UniProtKB/TrEMBL
APP_E2
UniProtKB/TrEMBL
APP_INTRA
UniProtKB/TrEMBL
SMART
A4_EXTRA
UniProtKB/TrEMBL
Superfamily-SCOP
A heparin-binding domain
UniProtKB/TrEMBL
Amyloid beta a4 protein copper binding domain (domain 2)
UniProtKB/TrEMBL
CAPPD, an extracellular domain of amyloid beta A4 protein
UniProtKB/TrEMBL
UniProt
A0AAX6PSS7
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6PU42
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6R2A7
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6R416
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6R569
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6R5I0
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6RD67
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6RGM8
ENTREZGENE, UniProtKB/TrEMBL
A0AAX6RGZ4
ENTREZGENE, UniProtKB/TrEMBL
G5BXP2
ENTREZGENE, UniProtKB/TrEMBL