Atf7 (activating transcription factor 7) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Atf7 (activating transcription factor 7) Heterocephalus glaber
Analyze
Symbol: Atf7
Name: activating transcription factor 7
RGD ID: 18905202
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); enzyme binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN heart development (ortholog); hematopoietic progenitor cell differentiation (ortholog); hepatocyte apoptotic process (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleoplasm (ortholog); RNA polymerase II transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclic AMP-dependent transcription factor ATF-7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,613,487 - 1,706,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,604,083 - 1,705,739 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Atf7Naked Mole-Ratcolorectal cancer disease_progressionISOATF7 (Homo sapiens)9068941 RGDPMID:26148593 and REF_RGD_ID:11055686
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Atf7Naked Mole-RatNeurodevelopmental Disorders  ISOATF7 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868


Biological Process
1 to 9 of 9 rows

  
1 to 9 of 9 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Atf7Naked Mole-Ratnucleoplasm located_inISOATF7 (Homo sapiens)9068941 PMID:17264123UniProtPMID:17264123
Atf7Naked Mole-Ratnucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
Atf7Naked Mole-Ratnucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
Atf7Naked Mole-Ratnucleus located_inIEAUniRule:UR001116761150520179 UniProtGO_REF:0000104
Atf7Naked Mole-RatRNA polymerase II transcription regulator complex part_ofISOATF7 (Homo sapiens)9068941 PMID:20102225ComplexPortalPMID:20102225

Molecular Function
1 to 20 of 22 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Atf7Naked Mole-RatDNA binding enablesIEAUniRule:UR001116761150520179 UniProtGO_REF:0000104
Atf7Naked Mole-RatDNA binding enablesIEAUniProtKB-KW:KW-0238150520179 UniProtGO_REF:0000043
Atf7Naked Mole-RatDNA-binding transcription factor activity enablesIEAUniRule:UR001116761150520179 UniProtGO_REF:0000104
Atf7Naked Mole-RatDNA-binding transcription factor activity enablesIEAInterPro:IPR004827 and InterPro:IPR046347150520179 InterProGO_REF:0000002
Atf7Naked Mole-RatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISOATF7 (Homo sapiens)9068941 PMID:8288576NTNU_SBPMID:8288576
Atf7Naked Mole-Ratenzyme binding enablesISOUniProtKB:Q96EB69068941 PMID:23382074UniProtPMID:23382074
Atf7Naked Mole-Ratmitogen-activated protein kinase binding enablesISOATF7 (Homo sapiens)9068941 PMID:10376527UniProtPMID:10376527
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:P459849068941 PMID:10376527UniProtPMID:10376527
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:P188479068941 PMID:30833792IntActPMID:30833792
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:P01100 and UniProtKB:P054129068941 PMID:25609649IntActPMID:25609649
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:P06734 more ...9068941 PMID:25416956IntActPMID:25416956
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:P054129068941 PMID:35271311IntActPMID:35271311
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:O14867 more ...9068941 PMID:20102225IntActPMID:20102225
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:Q9NX409068941 PMID:20195357IntActPMID:20195357
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:O14867 more ...9068941 PMID:33961781IntActPMID:33961781
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:Q165149068941 PMID:17264123UniProtPMID:17264123
Atf7Naked Mole-Ratprotein binding enablesISOUniProtKB:O002689068941 PMID:15735663UniProtPMID:15735663
Atf7Naked Mole-RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOATF7 (Homo sapiens)9068941 PMID:8288576NTNU_SBPMID:8288576
Atf7Naked Mole-Ratsequence-specific double-stranded DNA binding enablesISOATF7 (Homo sapiens)9068941 PMID:28473536ARUK-UCLPMID:28473536
Atf7Naked Mole-Rattranscription cis-regulatory region binding enablesISOATF7 (Homo sapiens)9068941 PMID:17264123UniProtPMID:17264123
1 to 20 of 22 rows

PMID:30032202  



Atf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,613,487 - 1,706,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,604,083 - 1,705,739 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ATF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,507,856 - 53,626,382 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,507,856 - 53,626,410 (-)EnsemblGRCh38hg38GRCh38
GRCh371253,901,640 - 54,020,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,196,026 - 52,306,403 (-)NCBINCBI36Build 36hg18NCBI36
Build 341252,196,027 - 52,306,405NCBI
Celera1253,556,201 - 53,670,237 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,941,222 - 51,059,806 (-)NCBIHuRef
CHM1_11253,868,696 - 53,987,260 (-)NCBICHM1_1
T2T-CHM13v2.01253,473,861 - 53,592,424 (-)NCBIT2T-CHM13v2.0
Atf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,434,381 - 102,533,899 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,434,381 - 102,533,899 (-)EnsemblGRCm39 Ensembl
GRCm3815102,525,946 - 102,625,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,525,946 - 102,625,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715102,367,074 - 102,455,852 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,364,677 - 102,453,455 (-)NCBIMGSCv36mm8
Celera15104,694,388 - 104,783,409 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.66NCBI
Atf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,537,351 - 135,649,188 (-)NCBIGRCr8
mRatBN7.27133,660,491 - 133,750,902 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,663,294 - 133,750,848 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,419,512 - 135,506,589 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,648,883 - 137,735,950 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,635,114 - 137,722,181 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07144,131,382 - 144,223,463 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,136,325 - 144,223,429 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,923,377 - 142,016,052 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,283,187 - 141,372,637 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,351,602 - 141,448,693 (-)NCBI
Celera7130,091,319 - 130,178,104 (-)NCBICelera
Cytogenetic Map7q36NCBI
Atf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458803,738 - 898,967 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955458803,738 - 898,847 (-)NCBIChiLan1.0ChiLan1.0
LOC100981854
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,559,286 - 40,676,753 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,556,050 - 40,673,517 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,128,031 - 35,245,505 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11235,914,378 - 36,026,225 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1235,914,378 - 36,021,141 (+)Ensemblpanpan1.1panPan2
LOC607149
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,617,466 - 1,711,356 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,617,289 - 1,706,637 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,543,239 - 44,632,547 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,621,590 - 1,710,939 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,621,533 - 1,710,913 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,638,801 - 1,728,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,621,077 - 1,711,380 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,944,942 - 45,034,279 (-)NCBIUU_Cfam_GSD_1.0
LOC101960773
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,279,991 - 62,381,384 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,785,763 - 10,884,795 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,780,826 - 10,884,806 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,728,694 - 18,838,542 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,726,329 - 18,838,670 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2519,164,389 - 19,285,213 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238406
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,608,653 - 49,728,702 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,618,136 - 49,728,289 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,321,751 - 196,441,009 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.






Ensembl Acc Id: ENSHGLT00000002183   ⟹   ENSHGLP00000002135
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249041,613,487 - 1,706,549 (-)Ensembl
RefSeq Acc Id: XM_004872752   ⟹   XP_004872809
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,608,363 - 1,705,739 (-)NCBI
RefSeq Acc Id: XM_004872753   ⟹   XP_004872810
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,608,363 - 1,705,345 (-)NCBI
RefSeq Acc Id: XR_001182827
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,604,083 - 1,705,739 (-)NCBI
RefSeq Acc Id: XR_206384
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,608,363 - 1,705,739 (-)NCBI
Protein RefSeqs XP_004872809 (Get FASTA)   NCBI Sequence Viewer  
  XP_004872810 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002135
RefSeq Acc Id: XP_004872809   ⟸   XM_004872752
- UniProtKB: G5BIF1 (UniProtKB/TrEMBL),   A0AAX6QDQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872810   ⟸   XM_004872753
- UniProtKB: G5BIF1 (UniProtKB/TrEMBL),   A0AAX6QDQ1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000002135   ⟸   ENSHGLT00000002183



1 to 24 of 24 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000001620 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000002183 ENTREZGENE
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
  bZIP_transcription_factors UniProtKB/TrEMBL
  TF_CRE-BP1-typ UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Atf7 ENTREZGENE
PANTHER CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/TrEMBL
PIRSF ATF2_CRE-BP1 UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP beta-beta-alpha zinc fingers UniProtKB/TrEMBL
  Leucine zipper domain UniProtKB/TrEMBL
UniProt A0AAX6QDQ1 ENTREZGENE, UniProtKB/TrEMBL
  G5BIF1 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows