Usp36 (ubiquitin specific peptidase 36) - Rat Genome Database

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Gene: Usp36 (ubiquitin specific peptidase 36) Heterocephalus glaber
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Symbol: Usp36
Name: ubiquitin specific peptidase 36
RGD ID: 18905099
Description: ENCODES a protein that exhibits histone H2B deubiquitinase activity (ortholog); K48-linked deubiquitinase activity (ortholog); INVOLVED IN chromatin organization (ortholog); negative regulation of macroautophagy (ortholog); nucleolus organization (ortholog); ASSOCIATED WITH idiopathic generalized epilepsy (ortholog); FOUND IN cytoplasm (ortholog); nuclear speck (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ubiquitin carboxyl-terminal hydrolase 36
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248018,176,902 - 8,211,592 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248018,177,164 - 8,214,169 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)
nuclear speck  (ISO)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Usp36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248018,176,902 - 8,211,592 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248018,177,164 - 8,214,169 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
USP36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381778,787,381 - 78,841,439 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1778,787,381 - 78,841,441 (-)EnsemblGRCh38hg38GRCh38
GRCh371776,783,463 - 76,837,521 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361774,304,560 - 74,348,564 (-)NCBINCBI36Build 36hg18NCBI36
Build 341774,295,143 - 74,348,457NCBI
Celera1773,390,685 - 73,434,689 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1772,215,406 - 72,259,387 (-)NCBIHuRef
CHM1_11776,856,878 - 76,900,907 (-)NCBICHM1_1
T2T-CHM13v2.01779,682,181 - 79,736,241 (-)NCBIT2T-CHM13v2.0
Usp36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911118,150,477 - 118,181,086 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11118,150,477 - 118,181,070 (-)EnsemblGRCm39 Ensembl
GRCm3811118,259,651 - 118,290,260 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11118,259,651 - 118,290,244 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711118,120,967 - 118,151,558 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611118,075,743 - 118,105,500 (-)NCBIMGSCv36mm8
Celera11130,004,579 - 130,035,210 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.06NCBI
Usp36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810103,995,970 - 104,027,492 (-)NCBIGRCr8
mRatBN7.210103,497,349 - 103,528,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,497,349 - 103,528,877 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10108,597,760 - 108,629,288 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010108,060,891 - 108,092,419 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010103,418,070 - 103,449,598 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010107,292,828 - 107,324,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10107,292,828 - 107,324,355 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010106,927,771 - 106,959,353 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,264,874 - 108,296,384 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110108,281,139 - 108,310,782 (-)NCBI
Celera10102,057,521 - 102,089,067 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Usp36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555063,824,556 - 3,862,098 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555063,824,598 - 3,861,919 (+)NCBIChiLan1.0ChiLan1.0
USP36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21994,843,897 - 94,889,092 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11799,673,947 - 99,719,102 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01772,871,379 - 72,916,560 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11778,416,541 - 78,461,683 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1778,416,541 - 78,461,683 (-)Ensemblpanpan1.1panPan2
USP36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.192,547,316 - 2,587,360 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl92,550,452 - 2,585,108 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha93,204,251 - 3,244,344 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.093,198,025 - 3,238,153 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl93,198,174 - 3,237,961 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.193,221,527 - 3,261,605 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.093,346,088 - 3,386,118 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.093,427,024 - 3,467,073 (+)NCBIUU_Cfam_GSD_1.0
Usp36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056023,184,165 - 3,217,117 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365943,194,482 - 3,228,748 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365943,194,842 - 3,228,701 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl123,309,237 - 3,348,525 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1123,309,176 - 3,348,531 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2123,348,808 - 3,388,371 (+)NCBISscrofa10.2Sscrofa10.2susScr3
USP36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11670,769,133 - 70,813,274 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1670,769,797 - 70,810,844 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607741,899,622 - 41,944,511 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000007835   ⟹   ENSHGLP00000007749
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248018,176,902 - 8,211,592 (-)Ensembl
RefSeq Acc Id: XM_004860835   ⟹   XP_004860892
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248018,177,164 - 8,214,159 (-)NCBI
RefSeq Acc Id: XM_004860837   ⟹   XP_004860894
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248018,177,164 - 8,214,169 (-)NCBI
RefSeq Acc Id: XM_021240988   ⟹   XP_021096647
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248018,177,164 - 8,214,159 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004860892 (Get FASTA)   NCBI Sequence Viewer  
  XP_004860894 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096647 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01015 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007749
RefSeq Acc Id: XP_004860894   ⟸   XM_004860837
- Peptide Label: isoform X2
- UniProtKB: G5AVF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096647   ⟸   XM_021240988
- Peptide Label: isoform X1
- UniProtKB: G5AVF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860892   ⟸   XM_004860835
- Peptide Label: isoform X1
- UniProtKB: G5AVF4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000007749   ⟸   ENSHGLT00000007835


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005619 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007835 ENTREZGENE
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
NCBI Gene Usp36 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
Superfamily-SCOP Cysteine proteinases UniProtKB/TrEMBL
UniProt G5AVF4 ENTREZGENE, UniProtKB/TrEMBL