Sltm (SAFB like transcription modulator) - Rat Genome Database

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Gene: Sltm (SAFB like transcription modulator) Heterocephalus glaber
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Symbol: Sltm
Name: SAFB like transcription modulator
RGD ID: 18904540
Description: ENCODES a protein that exhibits RNA binding (inferred); sequence-specific DNA binding (inferred); INVOLVED IN regulation of mRNA processing (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SAFB-like transcription modulator
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478113,042,831 - 13,090,493 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sltm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478113,042,831 - 13,090,493 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLTM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381558,879,050 - 58,933,679 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1558,879,050 - 58,933,679 (-)EnsemblGRCh38hg38GRCh38
GRCh371559,171,249 - 59,225,878 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361556,958,536 - 57,013,144 (-)NCBINCBI36Build 36hg18NCBI36
Celera1536,059,189 - 36,113,796 (-)NCBICelera
Cytogenetic Map15q22.1NCBI
HuRef1535,994,164 - 36,048,861 (-)NCBIHuRef
CHM1_11559,289,165 - 59,343,802 (-)NCBICHM1_1
T2T-CHM13v2.01556,681,092 - 56,735,731 (-)NCBIT2T-CHM13v2.0
Sltm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39970,449,717 - 70,499,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl970,450,036 - 70,499,516 (+)EnsemblGRCm39 Ensembl
GRCm38970,542,177 - 70,592,237 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl970,542,754 - 70,592,234 (+)EnsemblGRCm38mm10GRCm38
MGSCv37970,390,585 - 70,440,039 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36970,341,942 - 70,391,396 (+)NCBIMGSCv36mm8
Celera967,759,529 - 67,808,982 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map939.53NCBI
Sltm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8880,096,555 - 80,142,668 (+)NCBIGRCr8
mRatBN7.2871,215,995 - 71,261,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl871,216,612 - 71,261,825 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0876,977,698 - 77,022,847 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl876,977,822 - 77,022,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0876,059,815 - 76,105,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4875,020,876 - 75,066,611 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1875,079,798 - 75,085,656 (+)NCBI
Celera870,467,318 - 70,512,465 (-)NCBICelera
Cytogenetic Map8q24NCBI
Sltm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545015,691,463 - 15,736,709 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545015,691,472 - 15,748,123 (+)NCBIChiLan1.0ChiLan1.0
SLTM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21648,143,255 - 48,197,766 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11552,326,109 - 52,381,526 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01537,848,629 - 37,903,221 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11556,157,515 - 56,211,801 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1556,158,460 - 56,211,695 (-)Ensemblpanpan1.1panPan2
SLTM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13023,858,626 - 23,902,042 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3023,859,194 - 23,902,009 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3023,832,406 - 23,875,850 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03024,027,005 - 24,070,471 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3024,027,378 - 24,070,477 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13023,950,495 - 23,993,912 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03024,035,414 - 24,078,899 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03024,178,984 - 24,222,422 (-)NCBIUU_Cfam_GSD_1.0
Sltm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640102,190,074 - 102,234,347 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647120,039,081 - 20,081,721 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647120,038,137 - 20,082,410 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLTM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1113,084,008 - 113,136,599 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11113,085,095 - 113,140,604 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21125,132,697 - 125,167,732 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLTM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12624,583,671 - 24,639,455 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2624,583,699 - 24,642,460 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048116,681,827 - 116,738,424 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004855731   ⟹   XP_004855788
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,966 - 13,090,493 (+)NCBI
RefSeq Acc Id: XM_004855732   ⟹   XP_004855789
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,966 - 13,089,548 (+)NCBI
RefSeq Acc Id: XM_013076193   ⟹   XP_012931647
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,832 - 13,090,493 (+)NCBI
RefSeq Acc Id: XM_013076194   ⟹   XP_012931648
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,833 - 13,090,493 (+)NCBI
RefSeq Acc Id: XM_021237156   ⟹   XP_021092815
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,831 - 13,090,493 (+)NCBI
RefSeq Acc Id: XM_021237157   ⟹   XP_021092816
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,831 - 13,090,493 (+)NCBI
RefSeq Acc Id: XM_021237158   ⟹   XP_021092817
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,831 - 13,090,493 (+)NCBI
RefSeq Acc Id: XM_021237159   ⟹   XP_021092818
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478113,042,832 - 13,090,493 (+)NCBI
RefSeq Acc Id: XP_021092815   ⟸   XM_021237156
- Peptide Label: isoform X4
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6RBP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092816   ⟸   XM_021237157
- Peptide Label: isoform X6
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6R6A4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092817   ⟸   XM_021237158
- Peptide Label: isoform X7
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6R5Q5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012931647   ⟸   XM_013076193
- Peptide Label: isoform X3
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6R2W7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092818   ⟸   XM_021237159
- Peptide Label: isoform X8
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6RAH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012931648   ⟸   XM_013076194
- Peptide Label: isoform X5
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6QZQ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855788   ⟸   XM_004855731
- Peptide Label: isoform X1
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6PNX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855789   ⟸   XM_004855732
- Peptide Label: isoform X2
- UniProtKB: G5AQ65 (UniProtKB/TrEMBL),   A0AAX6PP26 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018512 ENTREZGENE
Ensembl Transcript ENSHGLT00000026229 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
  SAP domain UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SAF_Modulators UniProtKB/TrEMBL
  SAP_dom UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/TrEMBL
NCBI Gene Sltm ENTREZGENE
PANTHER SAFB-LIKE TRANSCRIPTION MODULATOR UniProtKB/TrEMBL
  SCAFFOLD ATTACHMENT FACTOR B-RELATED UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
Superfamily-SCOP RNA-binding domain, RBD UniProtKB/TrEMBL
  SAP domain UniProtKB/TrEMBL
UniProt A0AAX6PNX1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PP26 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QZQ8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R2W7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R5Q5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R6A4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RAH5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RBP9 ENTREZGENE, UniProtKB/TrEMBL
  G5AQ65 ENTREZGENE, UniProtKB/TrEMBL